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P44533 (URK_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Uridine kinase
EC=2.7.1.48
Alternative name(s):
Cytidine monophosphokinase
Uridine monophosphokinase
Gene names
Name:udk
Ordered Locus Names:HI_0132
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + uridine = ADP + UMP. HAMAP MF_00551

ATP + cytidine = ADP + CMP. HAMAP MF_00551

Pathway

Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3. HAMAP MF_00551

Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1. HAMAP MF_00551

Subcellular location

Cytoplasm By similarity HAMAP MF_00551.

Sequence similarities

Belongs to the uridine kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphotransferase activity, alcohol group as acceptor

Inferred from electronic annotation. Source: InterPro

uridine kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 213213Uridine kinase HAMAP MF_00551
PRO_0000164474

Regions

Nucleotide binding13 – 208ATP Potential

Sequences

Sequence LengthMass (Da)Tools
P44533 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 483B844ADA41E4D9

FASTA21324,284
        10         20         30         40         50         60 
MSNPSCIIIA ITGASASGKS SIASTVHKEL CNELGCQEIG IITEDSYYKD QSHLEMTERV 

        70         80         90        100        110        120 
KTNYDHPNSM DRDLLIQHLK NLKNGSAVDV PVYSYVEHTR TNETTHFTPK RIVILEGILL 

       130        140        150        160        170        180 
LTDERVRQLA DISVFVDTPL DICFIRRLQR DMEERGRSLQ SVIDQYRATV RPMFLQFIEP 

       190        200        210 
SKQYADIVIP RGGKNRIAIN MLKAQILHLL NQK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L42023 Genomic DNA. Translation: AAC21804.1.
PIRI64049.
RefSeqNP_438301.1. NC_000907.1.

3D structure databases

ProteinModelPortalP44533.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID951039.
GenomeReviewsGene locus HI_0132 in contig L42023_GR.
KEGGhin:HI0132.
PATRIC20188751. VBIHaeInf48452_0134.
TIGRHI_0132.

Phylogenomic databases

HOGENOMHBG527126.
OMADQTHLTM.
PhylomeDBP44533.
ProtClustDBPRK05480.

Enzyme and pathway databases

BioCycHINF71421:HI_0132-MONOMER.

Family and domain databases

HAMAPMF_00551. Uridine_kinase.
[Tree]
InterProIPR006083. PRK/URK.
IPR000764. Uridine_kinase.
[Graphical view]
KOK00876.
PfamPF00485. PRK. 1 hit.
[Graphical view]
PRINTSPR00988. URIDINKINASE.
TIGRFAMsTIGR00235. Udk. 1 hit.
ProtoNetSearch...

Entry information

Entry nameURK_HAEIN
AccessionPrimary (citable) accession number: P44533
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: January 25, 2012
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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