P44498 (TESB_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acyl-CoA thioesterase 2
EC=3.1.2.-

Alternative name(s):
Acyl-CoA thioesterase II
Short name=TEII

Gene names

Name:	tesB
Ordered Locus Names:	HI_0076

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	286 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known By similarity.
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the C/M/P thioester hydrolase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	acyl-CoA metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	hydrolase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 286	286	Acyl-CoA thioesterase 2		PRO_0000202146
Sites
	Active site	58	1	By similarity
	Active site	204	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P44498 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 529390BF7189CDD7	FASTA	286	32,406
	10 20 30 40 50 60 MSDILNNLIH LLKLEKIDDL IFRGESQDLG FRQVFGGQVV AQALSAAMQV APEDRILHSC 70 80 90 100 110 120 HAYFLAPGDS QYPIIYDVET LREGRNFSAL CVKAIQHKNT ICHVTASFQV PEKGFEHQNT 130 140 150 160 170 180 MPNVGAPEDF TDENVMLQKV AQTLPEPLNE KFAAERPFEV RTKYLNNPFN GTKLPAEQYS 190 200 210 220 230 240 WFKTNGETPL DIKIQQCLLA YFSDFHCILT ALHPHEKGFL QKGMKVATID HSIWFHRPFD 250 260 270 280 LNHWHLHAIE SNNAFGGRGL AQGQIFSQDG QLIATTQQEG LIRFSE

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC21752.1.
PIR	B64047.
RefSeq	NP_438249.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P44498.
SMR	P44498. Positions 2-285.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	950974.
GenomeReviews	Gene locus HI_0076 in contig L42023_GR.
KEGG	hin:HI0076.
NMPDR	fig|71421.1.peg.75.
PATRIC	20188607. VBIHaeInf48452_0077.
TIGR	HI_0076.
Phylogenomic databases
HOGENOM	HBG736737.
OMA	HKNTICH.
ProtClustDB	CLSK870160.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0076-MONOMER.
Family and domain databases
InterPro	IPR003703. Acyl_CoA_thio. [Graphical view]
KO	K10805.
PANTHER	PTHR11066. Acyl_CoA_thio. 1 hit.
Pfam	PF02551. Acyl_CoA_thio. 2 hits. [Graphical view]
TIGRFAMs	TIGR00189. TesB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TESB_HAEIN

Accession

Primary (citable) accession number: P44498

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	January 25, 2012
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program