Skip Header

Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot P44493 (AMIB_HAEIN)

Last modified January 19, 2010. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable N-acetylmuramoyl-L-alanine amidase amiB
    EC=3.5.1.28
Gene names
Name: amiB
Ordered Locus Names: HI0066
OrganismHaemophilus influenzae [Complete proteome] [HAMAP]
Taxonomic identifier727 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length432 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Cell-wall hydrolase probably involved in cell-wall hydrolysis, septation or recycling By similarity.

Catalytic activity

Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.

Subcellular location

Secreted Potential.

Domain

LysM repeats are thought to be involved in peptidoglycan binding.

Sequence similarities

Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.

Contains 2 LysM repeats.

Ontologies

Keywords
   Biological processCell wall biogenesis/degradation
   Cellular componentSecreted
   DomainRepeat
Signal
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcell wall macromolecule catabolic process

Inferred from electronic annotation. Source: InterPro

cellular cell wall organization

Inferred from electronic annotation. Source: UniProtKB-KW

peptidoglycan catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionN-acetylmuramoyl-L-alanine amidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 432412Probable N-acetylmuramoyl-L-alanine amidase amiB
PRO_0000006464

Regions

Repeat294 – 33643LysM 1
Repeat387 – 43044LysM 2

Sequences

Sequence LengthMass (Da)Tools
P44493-1 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 008D918A0E1EE81D

FASTA43249,109
        10         20         30         40         50         60 
MKTKILFFLF FSTFSFSIFA APITIAIDPG HGGKDPGAIS RNLGIYEKNV TLSIAKELKA 

        70         80         90        100        110        120 
LLDKDPHFRG VLTRKSDYYI SVPERSEIAR KFKANYLISI HADSSKSPDR RGASVWVLSN 

       130        140        150        160        170        180 
RRANDEMGQW LEDDEKRSEL LGGAGKVLSH NNDKYLDQTV LDLQFGHSQR TGYVLGEHIL 

       190        200        210        220        230        240 
HHFAKVTTLS RSTPQHASLG VLRSPDIPSV LVETGFLSNS EEEKKLNSQT YRRRIAYMIY 

       250        260        270        280        290        300 
EGLVAFHSGK TNTLVKDNLV QNIKQNDIKK SGKNNRTSEQ NINEDNIKDS GIRHIVKKGE 

       310        320        330        340        350        360 
SLGSLSNKYH VKVSDIIKLN QLKRKTLWLN ESIKIPDNVE IKNKSLTIKE NDFHKKQNSL 

       370        380        390        400        410        420 
VNNTNKDLKK EKNTQTNNQK NIIPLYHKVT KNQTLYAISR EYNIPVNILL SLNPHLKNGK 

       430 
VITGQKIKLR EK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC21744.1.
PIRD64046.
RefSeqNP_438239.1.

3D structure databases

SMRP44493. Positions 24-247.
ModBaseSearch...

Genome annotation databases

GeneID950965.
GenomeReviewsGene locus HI0066 in contig L42023_GR.
KEGGhin:HI0066.
NMPDRfig|71421.1.peg.65.
TIGRHI0066.

Phylogenomic databases

HOGENOMHBG656726.
OMAQKIKLRE.

Enzyme and pathway databases

BioCycHINF71421:HI_0066-MONOMER.
BRENDA3.5.1.28. 109.

Family and domain databases

InterProIPR002508. CW_Hdrlase/autolysin_cat.
IPR018392. Peptidoglycan-bd_lysin.
IPR002482. Peptidoglycan-bd_Lysin_sg.
[Graphical view]
Gene3DG3DSA:3.40.630.40. Cell_wall_OHase/autolysin_cat. 1 hit.
PfamPF01520. Amidase_3. 1 hit.
PF01476. LysM. 2 hits.
[Graphical view]
SMARTSM00646. Ami_3. 1 hit.
SM00257. LysM. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAMIB_HAEIN
AccessionPrimary (citable) accession number: P44493
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: January 19, 2010
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents