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P44493 (AMIB_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable N-acetylmuramoyl-L-alanine amidase AmiB
EC=3.5.1.28
Gene names
Name:amiB
Ordered Locus Names:HI_0066
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus ›

Protein attributes

Sequence length432 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell-wall hydrolase involved in septum cleavage during cell division By similarity.

Catalytic activity

Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.

Subcellular location

Periplasm By similarity.

Domain

LysM repeats are thought to be involved in peptidoglycan binding.

Sequence similarities

Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.

Contains 2 LysM repeats.

Ontologies

Keywords
   Biological processCell wall biogenesis/degradation
   Cellular componentPeriplasm
   DomainRepeat
Signal
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcell wall macromolecule catabolic process

Inferred from electronic annotation. Source: InterPro

peptidoglycan catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionN-acetylmuramoyl-L-alanine amidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 432412Probable N-acetylmuramoyl-L-alanine amidase AmiB
PRO_0000006464

Regions

Repeat294 – 33643LysM 1
Repeat387 – 43044LysM 2

Sequences

Sequence LengthMass (Da)Tools
P44493 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 008D918A0E1EE81D

FASTA43249,109
        10         20         30         40         50         60 
MKTKILFFLF FSTFSFSIFA APITIAIDPG HGGKDPGAIS RNLGIYEKNV TLSIAKELKA 

        70         80         90        100        110        120 
LLDKDPHFRG VLTRKSDYYI SVPERSEIAR KFKANYLISI HADSSKSPDR RGASVWVLSN 

       130        140        150        160        170        180 
RRANDEMGQW LEDDEKRSEL LGGAGKVLSH NNDKYLDQTV LDLQFGHSQR TGYVLGEHIL 

       190        200        210        220        230        240 
HHFAKVTTLS RSTPQHASLG VLRSPDIPSV LVETGFLSNS EEEKKLNSQT YRRRIAYMIY 

       250        260        270        280        290        300 
EGLVAFHSGK TNTLVKDNLV QNIKQNDIKK SGKNNRTSEQ NINEDNIKDS GIRHIVKKGE 

       310        320        330        340        350        360 
SLGSLSNKYH VKVSDIIKLN QLKRKTLWLN ESIKIPDNVE IKNKSLTIKE NDFHKKQNSL 

       370        380        390        400        410        420 
VNNTNKDLKK EKNTQTNNQK NIIPLYHKVT KNQTLYAISR EYNIPVNILL SLNPHLKNGK 

       430 
VITGQKIKLR EK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L42023 Genomic DNA. Translation: AAC21744.1.
PIRD64046.
RefSeqNP_438239.1. NC_000907.1.

3D structure databases

ProteinModelPortalP44493.
ModBaseSearch...

Protein-protein interaction databases

STRING71421.HI0066.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC21744; AAC21744; HI_0066.
GeneID950965.
KEGGhin:HI0066.
PATRIC20188587. VBIHaeInf48452_0067.

Phylogenomic databases

eggNOGCOG0860.
KOK01448.
OMADKDPHFR.
ProtClustDBCLSK2518355.

Family and domain databases

Gene3D3.40.630.40. 2 hits.
InterProIPR002508. CW_Hdrlase/autolysin_cat.
IPR018392. Peptidoglycan-bd_lysin.
IPR002482. Peptidoglycan-bd_Lysin_subgr.
[Graphical view]
PfamPF01520. Amidase_3. 1 hit.
PF01476. LysM. 2 hits.
[Graphical view]
SMARTSM00646. Ami_3. 1 hit.
SM00257. LysM. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAMIB_HAEIN
AccessionPrimary (citable) accession number: P44493
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 1, 2013
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

SIMILARITY comments

Index of protein domains and families

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