Reviewed,
UniProtKB/Swiss-Prot P44489 (UVRC_HAEIN)
Last modified
November 24, 2009.
Version 65.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: UvrABC system protein C Short name=Protein uvrC Alternative name(s): Excinuclease ABC subunit C | ||||
| Gene names |
| ||||
| Organism | Haemophilus influenzae [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 727 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus |
Protein attributes
| Sequence length | 609 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision By similarity. |
| Subunit structure | Interacts with uvrB in an incision complex By similarity. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the uvrC family. Contains 1 UVR domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | DNA damage DNA excision DNA repair SOS response |
| Cellular component | Cytoplasm |
| Molecular function | Excision nuclease |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | SOS response Inferred from electronic annotation. Source: HAMAP nucleotide-excision repairInferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell excinuclease repair complexInferred from electronic annotation. Source: InterPro |
| Molecular function | DNA binding Inferred from electronic annotation. Source: HAMAP excinuclease ABC activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 609 | 609 | UvrABC system protein C HAMAP MF_00203 | PRO_0000138304 | |||||
Regions | |||||||||
| Domain | 201 – 236 | 36 | UVR | ||||||
Sequences
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References
| [1] | "Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. Venter J.C.Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd. |
Cross-references
Sequence databases | |
|---|---|
| L42023 Genomic DNA. Translation: AAC21735.1. | |
| PIR | F64045. |
| RefSeq | NP_438230.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 950955. |
| GenomeReviews | Gene locus HI0057 in contig L42023_GR. |
| KEGG | hin:HI0057. |
| NMPDR | fig|71421.1.peg.56. |
| TIGR | HI0057. |
Phylogenomic databases | |
| HOGENOM | P44489. |
| OMA | LRDDKSF |
Enzyme and pathway databases | |
| BioCyc | HINF71421:HI_0057-MON. |
Family and domain databases | |
| HAMAP | MF_00203. [Tree] |
| InterPro | IPR000445. HhH_motif. IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif. IPR010994. RuvA_2-like. IPR001943. UvrB/C. IPR009055. UvrB_UvrC-bd_C. IPR004791. UvrC_ABC. IPR001162. UvrC_C. IPR000305. UvrC_N. [Graphical view] |
| Pfam | PF01541. GIY-YIG. 1 hit. PF00633. HHH. 1 hit. PF02151. UVR. 1 hit. PF08459. UvrC_HhH_N. 1 hit. [Graphical view] |
| SMART | SM00465. GIYc. 1 hit. SM00278. HhH1. 2 hits. [Graphical view] |
| TIGRFAMs | TIGR00194. uvrC. 1 hit. |
| PROSITE | PS50151. UVR. 1 hit. PS50164. UVRC_1. 1 hit. PS50165. UVRC_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | UVRC_HAEIN | ||||||||
| Accession | Primary (citable) accession number: P44489 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Haemophilus influenzae Haemophilus influenzae (strain Rd): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


