P44489 (UVRC_HAEIN) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 82.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: UvrABC system protein C Short name=Protein UvrC Alternative name(s): Excinuclease ABC subunit C | ||||
| Gene names |
| ||||
| Organism | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) | ||||
| Taxonomic identifier | 71421 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus |
Protein attributes
| Sequence length | 609 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision By similarity. HAMAP MF_00203 |
| Subunit structure | Interacts with UvrB in an incision complex By similarity. |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00203. |
| Sequence similarities | Belongs to the UvrC family. Contains 1 UVR domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | DNA damage DNA excision DNA repair SOS response |
| Cellular component | Cytoplasm |
| Molecular function | Excision nuclease |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | SOS response Inferred from electronic annotation. Source: UniProtKB-KW nucleotide-excision repairInferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell excinuclease repair complexInferred from electronic annotation. Source: InterPro |
| Molecular function | DNA binding Inferred from electronic annotation. Source: InterPro excinuclease ABC activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 609 | 609 | UvrABC system protein C HAMAP MF_00203 | PRO_0000138304 | |||||
Regions | |||||||||
| Domain | 201 – 236 | 36 | UVR | ||||||
Sequences
| ||||||||||||||||||
References
| [1] | "Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. Venter J.C.Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | L42023 Genomic DNA. Translation: AAC21735.1. |
| PIR | F64045. |
| RefSeq | NP_438230.1. NC_000907.1. |
3D structure databases | |
| ProteinModelPortal | P44489. |
| SMR | P44489. Positions 554-608. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 950955. |
| GenomeReviews | Gene locus HI_0057 in contig L42023_GR. |
| KEGG | hin:HI0057. |
| NMPDR | fig|71421.1.peg.56. |
| PATRIC | 20188567. VBIHaeInf48452_0057. |
| TIGR | HI_0057. |
Phylogenomic databases | |
| HOGENOM | HBG566029. |
| OMA | DVLYVGK. |
| PhylomeDB | P44489. |
| ProtClustDB | PRK00558. |
Enzyme and pathway databases | |
| BioCyc | HINF71421:HI_0057-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00203. UvrC. [Tree] |
| InterPro | IPR000445. HhH_motif. IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif. IPR010994. RuvA_2-like. IPR001943. UvrB/C. IPR009055. UvrB_UvrC-bd_C. IPR004791. UvrC_ABC. IPR001162. UvrC_C. IPR000305. UvrC_N. [Graphical view] |
| Gene3D | G3DSA:3.40.1440.10. G3DSA:3.40.1440.10. 1 hit. |
| KO | K03703. |
| PANTHER | PTHR11107:SF11. PTHR11107:SF11. 1 hit. |
| Pfam | PF01541. GIY-YIG. 1 hit. PF00633. HHH. 1 hit. PF02151. UVR. 1 hit. PF08459. UvrC_HhH_N. 1 hit. [Graphical view] |
| SMART | SM00465. GIYc. 1 hit. SM00278. HhH1. 2 hits. [Graphical view] |
| SUPFAM | SSF47781. RuvA_2_like. 1 hit. SSF46600. UvrB_C. 1 hit. SSF82771. UvrC_N. 1 hit. |
| TIGRFAMs | TIGR00194. UvrC. 1 hit. |
| PROSITE | PS50151. UVR. 1 hit. PS50164. UVRC_1. 1 hit. PS50165. UVRC_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | UVRC_HAEIN | ||||||||
| Accession | Primary (citable) accession number: P44489 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Haemophilus influenzae Haemophilus influenzae (strain Rd): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with