Reviewed, UniProtKB/Swiss-Prot P44482 (KDGK_HAEIN)

Names and originHide

Protein names

Recommended name:
2-dehydro-3-deoxygluconokinase
EC=2.7.1.45

Alternative name(s):
2-keto-3-deoxygluconokinase
3-deoxy-2-oxo-D-gluconate kinase
KDG kinase

Gene names

Name:	kdgK
Ordered Locus Names:	HI_0049

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributesHide

Sequence length	314 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)Hide

Catalytic activity	ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + 6-phospho-2-dehydro-3-deoxy-D-gluconate.
Sequence similarities	Belongs to the carbohydrate kinase pfkB family.

OntologiesHide

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	2-dehydro-3-deoxygluconokinase activity Inferred from electronic annotation. Source: EC ATP binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)Hide

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 314	314	2-dehydro-3-deoxygluconokinase		PRO_0000080087

SequencesHide

	Sequence		Length	Mass (Da)
	P44482-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 24CA631C8B0485F9	FASTA	314	35,462
	10 20 30 40 50 60 MKKIAFIGEC MIELNGKPFA EMWQSYGGDT LNSATYLSRV SSSKEIQVHY VSALGTDNLS 70 80 90 100 110 120 KQMLKYWQAD GIQTNWVLQD EQHQPGLYLI QLDAQGERTF LYWRNQSAAR YMVQHPDFAK 130 140 150 160 170 180 VIAELQQVDV IYLSGISLAI LPKNDRTFLI EQLSSLAKKG TEIVFDSNYR PKLWDSLEEA 190 200 210 220 230 240 QDCYLQLLPS VNIALVTFDD EQALWKDKTS RDTLERLHKI GIPKVIVKCG KNGAIFSDRY 250 260 270 280 290 300 LSQYGQVIPE PILNVVDTTS AGDSFNAGFL NGYLRNKSLE ICCQQGNRIA GIVIQHKGAI 310 IDKVAISHLQ SEFN

ReferencesHide

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-referencesHide

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC21727.1.
PIR	C64045.
RefSeq	NP_438222.1.
3D structure databases
SMR	P44482. Positions 2-300.
ModBase	Search...
Genome annotation databases
GeneID	950949.
GenomeReviews	Gene locus HI_0049 in contig L42023_GR.
KEGG	hin:HI0049.
NMPDR	fig|71421.1.peg.48.
TIGR	HI_0049.
Phylogenomic databases
HOGENOM	HBG697973.
OMA	YWQADGI.
ProtClustDB	CLSK892352.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0049-MONOMER.
BRENDA	2.7.1.45. 109.
Family and domain databases
InterPro	IPR011611. Carb/pur_kinase. IPR002173. Carboh/pur_kinase_PfkB_CS. [Graphical view]
Pfam	PF00294. PfkB. 1 hit. [Graphical view]
PROSITE	PS00583. PFKB_KINASES_1. False negative. PS00584. PFKB_KINASES_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry informationHide

Entry name

KDGK_HAEIN

Accession

Primary (citable) accession number: P44482

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	July 13, 2010
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)