P44481 (Y048_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized oxidoreductase HI_0048
EC=1.-.-.-

Gene names

Ordered Locus Names:

HI_0048

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	285 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 285	285	Uncharacterized oxidoreductase HI_0048		PRO_0000054841
Sites
	Active site	181	1	Proton acceptor By similarity
	Binding site	168	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	P44481 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 54440C3CD90595FC	FASTA	285	30,906
	10 20 30 40 50 60 MEFTMNIAAN HNLENKLIII TGAGGVLCSF LAKQLAYTKA NIALLDLNFE AADKVAKEIN 70 80 90 100 110 120 QSGGKAKAYK TNVLELENIK EVRNQIETDF GTCDILINGA GGNNPKATTD NEFHQFDLNE 130 140 150 160 170 180 TTRTFFDLDK SGIEFVFNLN YLGSLLPTQV FAKDMLGKQG ANIINISSMN AFTPLTKIPA 190 200 210 220 230 240 YSGAKAAISN FTQWLAVYFS KVGIRCNAIA PGFLVSNQNL ALLFDTEGKP TDRANKILTN 250 260 270 280 TPMGRFGESE ELLGALLFLI DENYSAFVNG VVLPVDGGFS AYSGV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.
[2]	"Two-dimensional map of the proteome of Haemophilus influenzae." Langen H., Takacs B., Evers S., Berndt P., Lahm H.W., Wipf B., Gray C., Fountoulakis M. Electrophoresis 21:411-429(2000) [PubMed: 10675023] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC21726.1.
PIR	B64045.
RefSeq	NP_438221.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P44481.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	950942.
GenomeReviews	Gene locus HI_0048 in contig L42023_GR.
KEGG	hin:HI0048.
NMPDR	fig|71421.1.peg.47.
PATRIC	20188549. VBIHaeInf48452_0048.
TIGR	HI_0048.
Phylogenomic databases
HOGENOM	HBG750976.
OMA	CGYMAKE.
ProtClustDB	PRK08277.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0048-MONOMER.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. IPR020904. Sc_DH/Rdtase_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PRINTS	PR00081. GDHRDH. PR00080. SDRFAMILY.
PROSITE	PS00061. ADH_SHORT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y048_HAEIN

Accession

Primary (citable) accession number: P44481

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	January 25, 2012
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program