Reviewed, UniProtKB/Swiss-Prot P44476 (MRED_HAEIN)

Names and origin

Protein names

Recommended name:
    Rod shape-determining protein mreD

Gene names

Name:	mreD
Ordered Locus Names:	HI0039

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	162 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the mreD family.

Ontologies

Keywords
Biological process	Cell shape
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 162	162	Rod shape-determining protein mreD		PRO_0000062773
Regions
	Transmembrane	5 – 25	21	Potential
	Transmembrane	30 – 50	21	Potential
	Transmembrane	56 – 76	21	Potential
	Transmembrane	105 – 125	21	Potential
	Transmembrane	132 – 152	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	P44476-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 3985BA4EA37BAAE6	FASTA	162	18,965
	10 20 30 40 50 60 MQTRFILQWF TILSFFVIAF VLELAPWPVG FQMLKPAWLV LVLLYWVLAI PNKVSIGWSF 70 80 90 100 110 120 LLGLTWDLIL GSTLGVHALV LSTSMYIIAK NYLILRNLSL WFQSLLVVLF VFIIRLLIFL 130 140 150 160 VEFSLHTAFF HWQAILGAFA SGLLWPWVFL LMRKIRRKVK LH

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L42023 Genomic DNA. Translation: AAC21717.1.
PIR	G64044.
RefSeq	NP_438212.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	950936.
GenomeReviews	Gene locus HI0039 in contig L42023_GR.
KEGG	hin:HI0039.
TIGR	HI0039.
Phylogenomic databases
HOGENOM	HBG701138.
OMA	YLVALNF.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0039-MON.
Family and domain databases
InterPro	IPR007227. Cell_shape_determining_MreD. [Graphical view]
Pfam	PF04093. MreD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MRED_HAEIN

Accession

Primary (citable) accession number: P44476

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	December 15, 2009
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)