P44476 (MRED_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Rod shape-determining protein mreD

Gene names

Name:	mreD
Ordered Locus Names:	HI_0039

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	162 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the mreD family.

Ontologies

Keywords
Biological process	Cell shape
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 162	162	Rod shape-determining protein mreD		PRO_0000062773
Regions
	Transmembrane	5 – 25	21	Helical; Potential
	Transmembrane	30 – 50	21	Helical; Potential
	Transmembrane	56 – 76	21	Helical; Potential
	Transmembrane	105 – 125	21	Helical; Potential
	Transmembrane	132 – 152	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P44476 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 3985BA4EA37BAAE6	FASTA	162	18,965
	10 20 30 40 50 60 MQTRFILQWF TILSFFVIAF VLELAPWPVG FQMLKPAWLV LVLLYWVLAI PNKVSIGWSF 70 80 90 100 110 120 LLGLTWDLIL GSTLGVHALV LSTSMYIIAK NYLILRNLSL WFQSLLVVLF VFIIRLLIFL 130 140 150 160 VEFSLHTAFF HWQAILGAFA SGLLWPWVFL LMRKIRRKVK LH

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC21717.1.
PIR	G64044.
RefSeq	NP_438212.1. NC_000907.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	950936.
GenomeReviews	Gene locus HI_0039 in contig L42023_GR.
KEGG	hin:HI0039.
PATRIC	20188529. VBIHaeInf48452_0039.
TIGR	HI_0039.
Phylogenomic databases
HOGENOM	HBG701138.
OMA	YLVALNF.
ProtClustDB	CLSK870680.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0039-MONOMER.
Family and domain databases
InterPro	IPR007227. Cell_shape_determining_MreD. [Graphical view]
KO	K03571.
Pfam	PF04093. MreD. 1 hit. [Graphical view]
TIGRFAMs	TIGR03426. Shape_MreD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MRED_HAEIN

Accession

Primary (citable) accession number: P44476

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	January 25, 2012
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program