Skip Header

Contribute Send feedback
Read comments (?) or add your own

P44470 (RLMH_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA large subunit methyltransferase H
EC=2.1.1.177
Alternative name(s):
23S rRNA (pseudouridine1915-N3)-methyltransferase
23S rRNA m3Psi1915 methyltransferase
rRNA (pseudouridine-N3-)-methyltransferase RlmH
Gene names
Name:rlmH
Ordered Locus Names:HI_0033
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length155 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA By similarity. HAMAP MF_00658

Catalytic activity

S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine. HAMAP MF_00658

S-adenosyl-L-methionine + pseudouridine(1915) in 23S rRNA = S-adenosyl-L-homocysteine + N(3)-methylpseudouridine(1915) in 23S rRNA. HAMAP MF_00658

Subunit structure

Homodimer By similarity. HAMAP MF_00658

Subcellular location

Cytoplasm Potential HAMAP MF_00658.

Sequence similarities

Belongs to the RNA methyltransferase RlmH family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processrRNA methylation

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmethyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 155155Ribosomal RNA large subunit methyltransferase H HAMAP MF_00658
PRO_0000198126

Sequences

Sequence LengthMass (Da)Tools
P44470 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: D147B9FA24389A1E

FASTA15517,250
        10         20         30         40         50         60 
MKITLIAVGT KMPSWVTTGF EEYQRRFPKD MPFELIEIPA GKRGKNADIK RILEQEGKAM 

        70         80         90        100        110        120 
LAACGKGKVV TLDIPGKPWT TPQLAEQLEA WKNDGRDVCL LIGGPEGLSP ECKAAAEQSW 

       130        140        150 
SLSPLTLPHP LVRVVVAESL YRAWSLTTNH PYHRE

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L42023 Genomic DNA. Translation: AAC21711.1.
PIRG64140.
RefSeqNP_438206.1. NC_000907.1.

3D structure databases

ProteinModelPortalP44470.
SMRP44470. Positions 1-155.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID950930.
GenomeReviewsGene locus HI_0033 in contig L42023_GR.
KEGGhin:HI0033.
PATRIC20188517. VBIHaeInf48452_0033.
TIGRHI_0033.

Phylogenomic databases

HOGENOMHBG622807.
OMATANHPYH.
ProtClustDBPRK00103.

Enzyme and pathway databases

BioCycHINF71421:HI_0033-MONOMER.

Family and domain databases

HAMAPMF_00658. 23SrRNA_methyltr_H.
[Tree]
InterProIPR016051. RlmH.
IPR003742. SPOUT_MeTrfase.
[Graphical view]
KOK00783.
PfamPF02590. SPOUT_MTase. 1 hit.
[Graphical view]
PIRSFPIRSF004505. MT_bac. 1 hit.
TIGRFAMsTIGR00246. TRNA_RlmH_YbeA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRLMH_HAEIN
AccessionPrimary (citable) accession number: P44470
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents