Reviewed, UniProtKB/Swiss-Prot P44468 (RODA_HAEIN)

Names and origin

Protein names

Recommended name:
    Rod shape-determining protein rodA

Gene names

Name:	mrdB
Synonyms:	rodA
Ordered Locus Names:	HI0031

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the ftsW/rodA/spoVE family.

Ontologies

Keywords
Biological process	Cell shape
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell cycle Inferred from electronic annotation. Source: InterPro regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 371	371	Rod shape-determining protein rodA		PRO_0000062717
Regions
	Transmembrane	17 – 37	21	Potential
	Transmembrane	51 – 71	21	Potential
	Transmembrane	75 – 95	21	Potential
	Transmembrane	111 – 131	21	Potential
	Transmembrane	142 – 162	21	Potential
	Transmembrane	172 – 192	21	Potential
	Transmembrane	275 – 295	21	Potential
	Transmembrane	313 – 333	21	Potential
	Transmembrane	337 – 357	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	P44468-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 85D5DDDE60B87E30	FASTA	371	41,164
	10 20 30 40 50 60 MEDKIPFWLR VWQRLHIDFW LFIGLLAITA YGMLVLYSAS GASETMFNSR IIQVLLGFIV 70 80 90 100 110 120 MLLMAQFPPR FYQRIAPYLY LIGFVLLILV DVIGTTSKGA QRWLDLGFIR FQPSEIVKLA 130 140 150 160 170 180 VPLMVAVYLG NRPLPPKLSE TFIAIAMILL PTLLVAIQPD LGTSILVSAS GLFVVFLAGM 190 200 210 220 230 240 SWWLILAAVI GLAGFIPIMW LYLMHDYQRT RVLTLLDPEK DPLGAGYHIL QSKIAIGSGG 250 260 270 280 290 300 LSGKGWMQGT QSQLEFLPEP HTDFIFAVMG EEHGMIGFLI LMAIYLFIIV RGLMIAVNAQ 310 320 330 340 350 360 TSFGRILAGA TTLIFFVYVF VNIGMVSGIL PVVGVPLPLF SYGGTSYVAI MASFGLLMSI 370 HTHKSQFMKR S

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L42023 Genomic DNA. Translation: AAC21709.1.
PIR	B64044.
RefSeq	NP_438204.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	950927.
GenomeReviews	Gene locus HI0031 in contig L42023_GR.
KEGG	hin:HI0031.
TIGR	HI0031.
Phylogenomic databases
HOGENOM	P44468.
OMA	NISKGAR
Enzyme and pathway databases
BioCyc	HINF71421:HI_0031-MON.
Family and domain databases
InterPro	IPR001182. Cell_cycle. IPR018365. Cell_cycle_FtsW-rel_CS. IPR011923. RodA_shape. [Graphical view]
Pfam	PF01098. FTSW_RODA_SPOVE. 1 hit. [Graphical view]
TIGRFAMs	TIGR02210. rodA_shape. 1 hit.
PROSITE	PS00428. FTSW_RODA_SPOVE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RODA_HAEIN

Accession

Primary (citable) accession number: P44468

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 24, 2009
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)