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P44462 (CITC_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
[Citrate [pro-3S]-lyase] ligase

EC=6.2.1.22
Alternative name(s):
Acetate:SH-citrate lyase ligase
Citrate lyase synthetase
Gene names
Name:citC
Ordered Locus Names:HI_0025
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length335 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Function

Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

Catalytic activity

ATP + acetate + [citrate (pro-3S)-lyase](thiol form) = AMP + diphosphate + [citrate (pro-3S)-lyase](acetyl form).

Sequence similarities

Contains 1 N-acetyltransferase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 335335[Citrate [pro-3S]-lyase] ligase
PRO_0000089771

Regions

Domain1 – 131131N-acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
P44462 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: BF7CE241C725C8EC

FASTA33538,495
        10         20         30         40         50         60 
MQFERISTEQ KKLSLIQTFL HQNALKLDEQ IEYFVVGYND NEQIVVCGGL AGNIIKCVAI 

        70         80         90        100        110        120 
DESLRGSGVA LQLITELVDL AYTLKRPHLF IYTKPEYATL FKSCGFYIIS DANPYVVLLE 

       130        140        150        160        170        180 
NSATRLQKQC SLWEKMRVDG NRIGSIVMNA NPFTLGHRYL IEQALQQCDH LHLFIVGEDA 

       190        200        210        220        230        240 
SQFSYTERFE MIQQGIFDLS NITLHSGSDY IISRATFPNY FLKDQLITDE SYFEIDLKLF 

       250        260        270        280        290        300 
RLHIAQALGI THRFVGTELN CPVTAEYNRQ MHYWLMDAEM NAPKINVIEI PRKTASNHII 

       310        320        330 
SASTVRKHLA EKNWAQLAEF VPMTTLNYLQ KCGRF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC21703.1.
PIRF64043.
RefSeqNP_438198.1. NC_000907.1.

3D structure databases

ProteinModelPortalP44462.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI0025.

Protocols and materials databases

DNASU950918.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC21703; AAC21703; HI_0025.
GeneID950918.
KEGGhin:HI0025.
PATRIC20188501. VBIHaeInf48452_0025.

Phylogenomic databases

eggNOGCOG3053.
KOK01910.
OMADCYTEID.
OrthoDBEOG6WHNRS.
PhylomeDBP44462.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
3.40.630.30. 1 hit.
InterProIPR016181. Acyl_CoA_acyltransferase.
IPR005216. Citrate_lyase_ligase.
IPR013166. Citrate_lyase_ligase_C.
IPR004821. Cyt_trans-like.
IPR000182. GNAT_dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF13508. Acetyltransf_7. 1 hit.
PF08218. Citrate_ly_lig. 1 hit.
[Graphical view]
PIRSFPIRSF005751. Acet_citr_lig. 1 hit.
SMARTSM00764. Citrate_ly_lig. 1 hit.
[Graphical view]
SUPFAMSSF55729. SSF55729. 1 hit.
TIGRFAMsTIGR00124. cit_ly_ligase. 1 hit.
TIGR00125. cyt_tran_rel. 1 hit.
PROSITEPS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCITC_HAEIN
AccessionPrimary (citable) accession number: P44462
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 9, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names