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P44453 (RSMC_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase C

EC=2.1.1.172
Alternative name(s):
16S rRNA m2G1207 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RsmC
Gene names
Name:rsmC
Ordered Locus Names:HI_0012
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length330 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle By similarity. HAMAP-Rule MF_01862

Catalytic activity

S-adenosyl-L-methionine + guanine(1207) in 16S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanine(1207) in 16S rRNA. HAMAP-Rule MF_01862

Subunit structure

Monomer By similarity. HAMAP-Rule MF_01862

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_01862.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmC family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function16S rRNA (guanine(1207)-N(2))-methyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

nucleic acid binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 330330Ribosomal RNA small subunit methyltransferase C HAMAP-Rule MF_01862
PRO_0000097491

Sequences

Sequence LengthMass (Da)Tools
P44453 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 7FF723E3993D9B69

FASTA33037,061
        10         20         30         40         50         60 
MISLESQVLE RHISFFDGKS VLFAGGISDS FPQTLASKCS SIQIWSCYFD YARTQSAVNF 

        70         80         90        100        110        120 
SVEFQGQADL IVYYWTKNKQ EVNFQLIQLL AQASIGQEIL IIGENRCGVR SVEKTLSPYG 

       130        140        150        160        170        180 
EIAKIDSARR CGLYHFSLQN KPHFELKNFW RTYQHSTLEN LTIYSLPGVF SAAELDTGTE 

       190        200        210        220        230        240 
LLLSTIDNKI KGKVLDLGCG AGVIGSMIKK RTPNAQITMT DIHAMALESA RKTLSENQLQ 

       250        260        270        280        290        300 
GEVYASDVFS DIEGKFDLII SNPPFHDGID TAYRAVTELI TQAKWHLNQG GELRIVANSF 

       310        320        330 
LPYPELLRQH FNDYQVLAQT GKFKVYSVKN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC21690.1.
PIRB64140.
RefSeqNP_438185.1. NC_000907.1.

3D structure databases

ProteinModelPortalP44453.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI0012.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC21690; AAC21690; HI_0012.
GeneID950903.
KEGGhin:HI0012.
PATRIC20188475. VBIHaeInf48452_0012.

Phylogenomic databases

eggNOGCOG2813.
KOK00564.
OMARHCQLWQ.
OrthoDBEOG67X1ZC.
ProtClustDBPRK09489.

Family and domain databases

HAMAPMF_01862. 16SrRNA_methyltr_C.
InterProIPR002052. DNA_methylase_N6_adenine_CS.
IPR013675. Mtase_sm_N.
IPR023543. rRNA_ssu_MeTfrase_C.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamPF05175. MTS. 1 hit.
PF08468. MTS_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRSMC_HAEIN
AccessionPrimary (citable) accession number: P44453
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names