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P44430

- DEOC_HAEIN

UniProt

P44430 - DEOC_HAEIN

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Protein

Deoxyribose-phosphate aldolase

Gene

deoC

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.By similarity

Catalytic activityi

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei154 – 1541Schiff-base intermediate with acetaldehydeBy similarity
Active sitei182 – 1821By similarity

GO - Molecular functioni

  1. deoxyribose-phosphate aldolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate catabolic process Source: UniProtKB-HAMAP
  2. deoxyribonucleotide catabolic process Source: InterPro
  3. deoxyribose phosphate catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

UniPathwayiUPA00002; UER00468.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxyribose-phosphate aldolase (EC:4.1.2.4)
Short name:
DERA
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase
Phosphodeoxyriboaldolase
Short name:
Deoxyriboaldolase
Gene namesi
Name:deoC
Ordered Locus Names:HI_1116
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 223223Deoxyribose-phosphate aldolasePRO_0000057234Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi71421.HI1116.

Structurei

3D structure databases

ProteinModelPortaliP44430.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0274.
KOiK01619.
OMAiYVYEDIR.
OrthoDBiEOG6QZMW5.
PhylomeDBiP44430.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00114. DeoC_type1.
InterProiIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/FbaB/lacD_aldolase.
IPR028581. DeoC_typeI.
[Graphical view]
PANTHERiPTHR10889. PTHR10889. 1 hit.
PfamiPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFiPIRSF001357. DeoC. 1 hit.
TIGRFAMsiTIGR00126. deoC. 1 hit.

Sequencei

Sequence statusi: Complete.

P44430-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTSNQLAQYI DHTALTAEKN EQDISTLCNE AIEHGFYSVC INSAYIPLAK
60 70 80 90 100
EKLAGSNVKI CTVVGFPLGA NLTSVKAFET QESIKAGANE IDMVINVGWI
110 120 130 140 150
KSQKWDEVKQ DIQAVFNACN GTPLKVILET CLLTKDEIVK ACEICKEIGV
160 170 180 190 200
AFVKTSTGFN KGGATVEDVA LMKNTVGNIG VKASGGVRDT ETALAMIKAG
210 220
ATRIGASAGI AIISGTQDTQ STY
Length:223
Mass (Da):23,614
Last modified:November 1, 1995 - v1
Checksum:iF631CACB7768FE18
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22770.1.
PIRiH64183.
RefSeqiNP_439273.1. NC_000907.1.
WP_005693439.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22770; AAC22770; HI_1116.
GeneIDi950311.
KEGGihin:HI1116.
PATRICi20190905. VBIHaeInf48452_1165.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22770.1 .
PIRi H64183.
RefSeqi NP_439273.1. NC_000907.1.
WP_005693439.1. NC_000907.1.

3D structure databases

ProteinModelPortali P44430.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI1116.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC22770 ; AAC22770 ; HI_1116 .
GeneIDi 950311.
KEGGi hin:HI1116.
PATRICi 20190905. VBIHaeInf48452_1165.

Phylogenomic databases

eggNOGi COG0274.
KOi K01619.
OMAi YVYEDIR.
OrthoDBi EOG6QZMW5.
PhylomeDBi P44430.

Enzyme and pathway databases

UniPathwayi UPA00002 ; UER00468 .

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00114. DeoC_type1.
InterProi IPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/FbaB/lacD_aldolase.
IPR028581. DeoC_typeI.
[Graphical view ]
PANTHERi PTHR10889. PTHR10889. 1 hit.
Pfami PF01791. DeoC. 1 hit.
[Graphical view ]
PIRSFi PIRSF001357. DeoC. 1 hit.
TIGRFAMsi TIGR00126. deoC. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiDEOC_HAEIN
AccessioniPrimary (citable) accession number: P44430
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 29, 2014
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3