Reviewed, UniProtKB/Swiss-Prot P44411 (BCP_HAEIN)

Names and origin

Protein names

Recommended name:
    Putative peroxiredoxin bcp
    EC=1.11.1.15
Alternative name(s):
    Thioredoxin reductase
    Bacterioferritin comigratory protein homolog

Gene names

Name:	bcp
Ordered Locus Names:	HI0254

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	155 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.
Sequence similarities	Belongs to the ahpC/TSA family. Contains 1 thioredoxin domain.

Ontologies

Keywords
Domain	Redox-active center
Molecular function	Oxidoreductase Peroxidase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	peroxiredoxin activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 155	155	Putative peroxiredoxin bcp		PRO_0000135137
Regions
	Domain	4 – 155	152	Thioredoxin
Sites
	Active site	46	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P44411-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 0E7AC12651107EA2	FASTA	155	17,553
	10 20 30 40 50 60 MNPLSVGNQA PAFTLLNQQE KFVSLSDFRG KKVLIYFYPK ALTPGCTTQA CGLRDSKSEL 70 80 90 100 110 120 DVLGLVVLGI SPDAPKKLAQ FIEKKELNFT LLSDPDHQVA EQFGVWGEKK FMGRTYDGIH 130 140 150 RISFLINESG TIMQVFDKFK IKDHHQMIID YLRSL

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L42023 Genomic DNA. Translation: AAC21920.1.
PIR	I64057.
RefSeq	NP_438423.1.
3D structure databases
HSSP	HSSP built from PDB template 1QQ2 based on UniProtKB Q63716.
ModBase	Search...
Genome annotation databases
GeneID	949377.
GenomeReviews	Gene locus HI0254 in contig L42023_GR.
KEGG	hin:HI0254.
NMPDR	fig|71421.1.peg.239.
TIGR	HI0254.
Phylogenomic databases
HOGENOM	P44411.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0254-MON.
Family and domain databases
InterPro	IPR000866. AhpC-TSA. IPR012335. Thioredoxin_fold. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
Pfam	PF00578. AhpC-TSA. 1 hit. [Graphical view]
PROSITE	PS51352. THIOREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

BCP_HAEIN

Accession

Primary (citable) accession number: P44411

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 25, 2008
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)