Recombination protein 2 - Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

Preferred order of sections

Names and origin

Protein names

Recommended name:
Recombination protein 2

Gene names

Name:	rec2
Synonyms:	rec-2
Ordered Locus Names:	HI_0061

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	788 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Function	Might contribute to transformation as a member of a membrane-bound pore complex at the base of the transformasome. It could directly interact with transforming DNA during translocation indirectly by participating in the assembly of the pore.
Subcellular location	Cell inner membrane; Multi-pass membrane protein Potential.

Ontologies

Keywords
Biological process	Competence Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	establishment of competence for transformation Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 788

788

Recombination protein 2

PRO_0000097224

Regions

Transmembrane

3 – 23

21

Helical; Potential

Transmembrane

27 – 47

21

Helical; Potential

Transmembrane

51 – 71

21

Helical; Potential

Transmembrane

226 – 246

21

Helical; Potential

Transmembrane

263 – 283

21

Helical; Potential

Transmembrane

313 – 333

21

Helical; Potential

Transmembrane

367 – 387

21

Helical; Potential

Transmembrane

401 – 421

21

Helical; Potential

Transmembrane

434 – 454

21

Helical; Potential

Transmembrane

456 – 476

21

Helical; Potential

Transmembrane

508 – 528

21

Helical; Potential

Experimental info

Sequence conflict

748 – 788

41

VENTA…GLSKE → GRKYRCFGASAGKFFSRPIR NPASSHKIFPLVCACNWIIK GIKGTMRAIFTIR in AAC13733. Ref.1

Sequences

Sequence

Length

Mass (Da)

Tools

P44408 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: F31104595CB4E47A
Show »

FASTA

788

89,356

        10         20         30         40         50         60 
MKLNLITLVV LLIVADLTLL FLPQPLLLPW QVALVIALVL IFLFIFLRRN FLVSLAFFVA 

        70         80         90        100        110        120 
SLGYFHYSAL SLSQQAQNIT AQKQVVTFKI QEILHQQDYQ TLIATATLEN NLQEQRIFLN 

       130        140        150        160        170        180 
WKAKEVPQLS EIWQAEISLR SLSARLNFGG FDRQQWYFSK GITAVGTVKS AVKIADVSSL 

       190        200        210        220        230        240 
RAEKLQQVKK QTEGLSLQGL LIALAFGERA WLDKTTWSIY QQTNTAHLIA ISGLHIGLAM 

       250        260        270        280        290        300 
GIGFCLARVV QVFFPTRFIH PYFPLVFGVL FALIYAYLAG FSVPTFRAIS ALVFVLFIQI 

       310        320        330        340        350        360 
MRRHYSPIQF FTLVVGFLLF CDPLMPLSVS FWLSCGAVGC LLLWYRYVPF SLFQWKNRPF 

       370        380        390        400        410        420 
SPKVRWIFSL FHLQFGLLLF FTPLQLFLFN GLSLSGFLAN FMAVPIYSFL LVPLILFAVF 

       430        440        450        460        470        480 
TNGTMFSWQL ANKLAEGITG LISVFQGNWL TVSFNLALGL TALCAGIFML IIWNIYREPE 

       490        500        510        520        530        540 
ISSSNWQIKR AKFFTLNLSK PLLKNERINV LRCSFGIILL CFTILLFKQL SKPTWQVDTL 

       550        560        570        580        590        600 
DVGQGLATLI VKNGKGILYD TGSSWRGGSM AELEILPYLQ REGIVLEKLI LSHDDNDHAG 

       610        620        630        640        650        660 
GASTILKAYP NVELITPSRK NYGENYRTFC TAGRDWHWQG LHFQILSPHN VVTRADNSHS 

       670        680        690        700        710        720 
CVILVDDGKN SVLLTGDAEA KNEQIFARTL GKIDVLQVGH HGSKTSTSEY LLSQVRPDVA 

       730        740        750        760        770        780 
IISSGRWNPW KFPHYSVMER LHRYKSAVEN TAVSGQVRVN FFQDRLEIQQ ARTKFSPWYA 


RVIGLSKE

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence of the rec-2 locus of Haemophilus influenzae: homologies to comE-ORF3 of Bacillus subtilis and msbA of Escherichia coli." Clifton S.W., McCarthy D., Roe B.A. Gene 146:95-100(1994) [PubMed: 8063112] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: BC200.
[2]	"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L20805 Genomic DNA. Translation: AAC13733.1. L42023 Genomic DNA. Translation: AAC21739.1.
PIR	I64045.
RefSeq	NP_438234.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P44408.
ModBase	Search...
Protein family/group databases
TCDB	3.A.11.2.2. bacterial competence-related DNA transformation transporter (DNA-T) family.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	950960.
GenomeReviews	Gene locus HI_0061 in contig L42023_GR.
KEGG	hin:HI0061.
NMPDR	fig\|71421.1.peg.60.
PATRIC	20188575. VBIHaeInf48452_0061.
TIGR	HI_0061.
Phylogenomic databases
HOGENOM	HBG390901.
OMA	HYGRITH.
PhylomeDB	P44408.
ProtClustDB	CLSK870276.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0061-MONOMER.
Family and domain databases
InterPro	IPR001279. Beta-lactamas-like. IPR004477. ComEC_N. IPR004797. Competence_ComEC/Rec2. [Graphical view]
KO	K02238.
Pfam	PF03772. Competence. 1 hit. PF00753. Lactamase_B. 1 hit. [Graphical view]
SMART	SM00849. Lactamase_B. 1 hit. [Graphical view]
TIGRFAMs	TIGR00360. ComEC_N-term. 1 hit. TIGR00361. ComEC_Rec2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

REC2_HAEIN

Accession

Primary (citable) accession number: P44408

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	January 25, 2012
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents