Skip Header

Contribute Send feedback
Read comments (?) or add your own

P44398 (XYLA_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Xylose isomerase
EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:HI_1112
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length439 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_00455

Subunit structure

Homotetramer By similarity. HAMAP MF_00455

Subcellular location

Cytoplasm HAMAP MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

xylose isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 439439Xylose isomerase HAMAP MF_00455
PRO_0000195779

Sites

Active site1011 By similarity
Active site1041 By similarity
Metal binding2321Magnesium 1 By similarity
Metal binding2681Magnesium 1 By similarity
Metal binding2681Magnesium 2 By similarity
Metal binding2711Magnesium 2 By similarity
Metal binding2961Magnesium 1 By similarity
Metal binding3071Magnesium 2 By similarity
Metal binding3091Magnesium 2 By similarity
Metal binding3391Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
P44398 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 24CD3CE4736A3EA6

FASTA43949,896
        10         20         30         40         50         60 
MTTYFDKIEK ISFEGEKSTN PFAFKHYDAN QVILGKTMAE HLRLAVCYWH TFCWNGNDMF 

        70         80         90        100        110        120 
GLGSLERSWQ KNSNLLAGAE QKADIAFEFL NKLGVPYYCF HDVDIAPEGN SVREYVQNFH 

       130        140        150        160        170        180 
HIVDILERKQ VETGVKLLWG TANCFTNPRY MSGAATNPNP EVFAWAATQV FNAMNATQRL 

       190        200        210        220        230        240 
GGENYVLWGG REGYETLLNT DLKREREQIG RFMQMVVEHK HKIGFKGTLL IEPKPQEPTK 

       250        260        270        280        290        300 
HQYDYDVATV YGFLKQFGLE KEIKVNIEAN HATLAGHTFQ HEIATACALD IFGSIDANRG 

       310        320        330        340        350        360 
DPQLGWDTDQ FPNSVEENTL VMYEILKHGG FTTGGFNFDA KIRRQSIDPY DLFYAHIGAI 

       370        380        390        400        410        420 
DVLALSLKRA AKMLQEETLQ KIVNERYAGW NSELGQHILQ GKTSLETLAQ LVQQKDLAPK 

       430 
PVSGQQEYLE NLVNQVIYS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L42023 Genomic DNA. Translation: AAC22766.1.
PIRISHIX. D64183.
RefSeqNP_439269.1. NC_000907.1.

3D structure databases

ProteinModelPortalP44398.
SMRP44398. Positions 3-439.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID950068.
GenomeReviewsGene locus HI_1112 in contig L42023_GR.
KEGGhin:HI1112.
PATRIC20190897. VBIHaeInf48452_1161.
TIGRHI_1112.

Phylogenomic databases

HOGENOMHBG297199.
OMALLGWDTD.
ProtClustDBPRK05474.

Enzyme and pathway databases

BioCycHINF71421:HI_1112-MONOMER.

Family and domain databases

HAMAPMF_00455. Xylose_isom_A.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01805.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR02630. Xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_HAEIN
AccessionPrimary (citable) accession number: P44398
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: January 25, 2012
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents