P44344 (RL3_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L3

Gene names

Name:	rplC
Synonyms:	rpl3
Ordered Locus Names:	HI_0777

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	208 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit By similarity. HAMAP-Rule MF_01325
Subunit structure	Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19 By similarity.
Post-translational modification	Methylated by PrmB By similarity.
Sequence similarities	Belongs to the ribosomal protein L3P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
PTM	Methylation
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 208	208	50S ribosomal protein L3 HAMAP-Rule MF_01325		PRO_0000077106
Amino acid modifications
	Modified residue	149	1	N5-methylglutamine By similarity

Sequences

	Sequence		Length	Mass (Da)
	P44344 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: BC73B3C0DC925228	FASTA	208	22,364
	10 20 30 40 50 60 MIGLVGRKVG MTRIFNEDGV SVPVTVIEIE ANRVTQVKTL ENDGYTAVQV TTGSKKANRV 70 80 90 100 110 120 TKPEAGHFVK AGVEAGRGLW EFRTEGEEFT LGQEINVDIF ADVKKVDVTG TSKGKGFQGG 130 140 150 160 170 180 VKRWNFRTQD ATHGNSLSHR VLGSIGQNQT PGRVFKGKKM AGHLGAERVT VQSLEVVRVD 190 200 AERKLLLVKG SVPGAINGDV IVKPAVKA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.
[2]	Zengel J.M., Vorozheikina D., Li X., Lindahl L. Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 192-208.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22436.1. U37797 Genomic DNA. Translation: AAB41510.1.
PIR	E64092.
RefSeq	NP_438936.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P44344.
SMR	P44344. Positions 1-208.
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI0777.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC22436; AAC22436; HI_0777.
GeneID	950820.
KEGG	hin:HI0777.
PATRIC	20190205. VBIHaeInf48452_0816.
Phylogenomic databases
eggNOG	COG0087.
KO	K02906.
OMA	KGMRMAG.
ProtClustDB	PRK00001.
Family and domain databases
HAMAP	MF_01325_B. Ribosomal_L3_B.
InterPro	IPR000597. Ribosomal_L3. IPR019927. Ribosomal_L3_bac/org-type. IPR019926. Ribosomal_L3_CS. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
PANTHER	PTHR11229. PTHR11229. 1 hit.
Pfam	PF00297. Ribosomal_L3. 1 hit. [Graphical view]
SUPFAM	SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR03625. L3_bact. 1 hit.
PROSITE	PS00474. RIBOSOMAL_L3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL3_HAEIN

Accession

Primary (citable) accession number: P44344

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program