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Protein

50S ribosomal protein L3

Gene

rplC

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L3UniRule annotation
Gene namesi
Name:rplCUniRule annotation
Synonyms:rpl3UniRule annotation
Ordered Locus Names:HI_0777
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 20820850S ribosomal protein L3PRO_0000077106Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei149 – 1491N5-methylglutamineUniRule annotation

Post-translational modificationi

Methylated by PrmB.UniRule annotation

Keywords - PTMi

Methylation

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.UniRule annotation

Protein-protein interaction databases

STRINGi71421.HI0777.

Structurei

3D structure databases

ProteinModelPortaliP44344.
SMRiP44344. Positions 1-208.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L3P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0087.
KOiK02906.
OMAiKRMAGRY.
OrthoDBiEOG6WDSMH.
PhylomeDBiP44344.

Family and domain databases

HAMAPiMF_01325_B. Ribosomal_L3_B.
InterProiIPR000597. Ribosomal_L3.
IPR019927. Ribosomal_L3_bac/org-type.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PANTHERiPTHR11229. PTHR11229. 1 hit.
PfamiPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
TIGRFAMsiTIGR03625. L3_bact. 1 hit.
PROSITEiPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P44344-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIGLVGRKVG MTRIFNEDGV SVPVTVIEIE ANRVTQVKTL ENDGYTAVQV
60 70 80 90 100
TTGSKKANRV TKPEAGHFVK AGVEAGRGLW EFRTEGEEFT LGQEINVDIF
110 120 130 140 150
ADVKKVDVTG TSKGKGFQGG VKRWNFRTQD ATHGNSLSHR VLGSIGQNQT
160 170 180 190 200
PGRVFKGKKM AGHLGAERVT VQSLEVVRVD AERKLLLVKG SVPGAINGDV

IVKPAVKA
Length:208
Mass (Da):22,364
Last modified:November 1, 1995 - v1
Checksum:iBC73B3C0DC925228
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22436.1.
U37797 Genomic DNA. Translation: AAB41510.1.
PIRiE64092.
RefSeqiNP_438936.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22436; AAC22436; HI_0777.
GeneIDi950820.
KEGGihin:HI0777.
PATRICi20190205. VBIHaeInf48452_0816.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22436.1.
U37797 Genomic DNA. Translation: AAB41510.1.
PIRiE64092.
RefSeqiNP_438936.1. NC_000907.1.

3D structure databases

ProteinModelPortaliP44344.
SMRiP44344. Positions 1-208.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0777.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22436; AAC22436; HI_0777.
GeneIDi950820.
KEGGihin:HI0777.
PATRICi20190205. VBIHaeInf48452_0816.

Phylogenomic databases

eggNOGiCOG0087.
KOiK02906.
OMAiKRMAGRY.
OrthoDBiEOG6WDSMH.
PhylomeDBiP44344.

Family and domain databases

HAMAPiMF_01325_B. Ribosomal_L3_B.
InterProiIPR000597. Ribosomal_L3.
IPR019927. Ribosomal_L3_bac/org-type.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PANTHERiPTHR11229. PTHR11229. 1 hit.
PfamiPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
TIGRFAMsiTIGR03625. L3_bact. 1 hit.
PROSITEiPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.
  2. Zengel J.M., Vorozheikina D., Li X., Lindahl L.
    Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 192-208.

Entry informationi

Entry nameiRL3_HAEIN
AccessioniPrimary (citable) accession number: P44344
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: January 7, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.