P44331 (RBSK_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribokinase
EC=2.7.1.15

Gene names

Name:	rbsK
Ordered Locus Names:	HI_0505

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	306 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + D-ribose = ADP + D-ribose 5-phosphate.
Pathway	Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the carbohydrate kinase PfkB family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	D-ribose catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribokinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 306	306	Ribokinase		PRO_0000080099

Sequences

	Sequence		Length	Mass (Da)
	P44331 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 3DCE8810827C8E84	FASTA	306	32,205
	10 20 30 40 50 60 MRKTLTVLGS INADHVISVP YFTKPGETLT GQNYQIAYGG KGANQAVAAA RLGAKVAFIS 70 80 90 100 110 120 CIGSDSIGKT MKNAFAQEGI DTTHINTVSQ EMTGMAFIQV AKSSENSIVL ASGANSHLSE 130 140 150 160 170 180 MVVRQSEAQI AQSDCLLMQL ETPLSGVELA AQIAKKNGVK VVLNPAPAQI LSDELLSLID 190 200 210 220 230 240 IITPNETEAE ILTGVEVADE QSAVKAASVF HDKGIETVMI TLGAKGVFVS RKGKSRIIKG 250 260 270 280 290 300 FCVQAIDTTA AGDTFNGGFV TALLEEKSFD EAIRFGQAAA AISVTKKGAQ SSIPTRQETL EFLEHA

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22163.1.
PIR	B64073.
RefSeq	NP_438663.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P44331.
SMR	P44331. Positions 4-305.
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI0505.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC22163; AAC22163; HI_0505.
GeneID	949575.
KEGG	hin:HI0505.
PATRIC	20189563. VBIHaeInf48452_0524.
Phylogenomic databases
eggNOG	COG0524.
KO	K00852.
OMA	IPTRQET.
ProtClustDB	PRK11142.
Enzyme and pathway databases
UniPathway	UPA00916; UER00889.
Family and domain databases
InterPro	IPR002173. Carboh/pur_kinase_PfkB_CS. IPR011877. D_ribokin_bac. IPR011611. PfkB_dom. IPR002139. Ribokinase. [Graphical view]
Pfam	PF00294. PfkB. 1 hit. [Graphical view]
PRINTS	PR00990. RIBOKINASE.
TIGRFAMs	TIGR02152. D_ribokin_bact. 1 hit.
PROSITE	PS00583. PFKB_KINASES_1. False negative. PS00584. PFKB_KINASES_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RBSK_HAEIN

Accession

Primary (citable) accession number: P44331

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 87 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program