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P44312

- G6PI_HAEIN

UniProt

P44312 - G6PI_HAEIN

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 2 (02 Nov 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei355 – 3551Proton donorBy similarity
    Active sitei387 – 3871By similarity
    Active sitei515 – 5151By similarity

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomerase (EC:5.3.1.9)
    Short name:
    GPI
    Alternative name(s):
    Phosphoglucose isomerase
    Short name:
    PGI
    Phosphohexose isomerase
    Short name:
    PHI
    Gene namesi
    Name:pgi
    Ordered Locus Names:HI_1576
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 549549Glucose-6-phosphate isomerasePRO_0000180650Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi71421.HI1576.

    Structurei

    3D structure databases

    ProteinModelPortaliP44312.
    SMRiP44312. Positions 23-549.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.Curated

    Phylogenomic databases

    eggNOGiCOG0166.
    KOiK01810.
    OMAiNCHFVAN.
    OrthoDBiEOG64R61J.
    PhylomeDBiP44312.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P44312-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKNINPTHTH AWKSLEAHKA ELSNITIQDL FKQEKNRFDD YSLTFNNQIL    50
    IDFSKNNINQ TTLSHLRQLA QECALDSAKE AMFTGEKINR TENRAVLHTA 100
    LRNRTNTPVL VDGKDVMPEV NAVLAKMKDF CQRIISGEWK GYTGKAITDV 150
    VNIGIGGSDL GPYMVTEALR PYKNHLNMHF VSNVDGTHIA ETLKKVNPET 200
    TLFLVASKTF TTQETMTNAQ SARDWLLKAA KDESAVAKHF AALSTNAKDV 250
    EKFGIDTNNM FEFWDWVGGR YSLWSAIGLS IALSIGFENF EALLNGAHEM 300
    DKHFLSTPIE QNIPTTLALV GLWNTNFLGA QTEAILPYDQ YLHRFAAYFQ 350
    QGNMESNGKY VDRDGNVIKN YQTGPIIWGE PGTNGQHAFY QLIHQGTTLI 400
    PCDFIAPAQR HNPLADHHNK LLSNFFAQTE ALAFGKTKEE VEAEFVKAGK 450
    SLDDVKNIVP FKVFTGNKPT NSILVQKITP FTLGALIAMY EHKIFVQGVI 500
    FNIFSFDQWG VELGKQLANR ILPELTDSEK VASHDSSTNG LINQFKAWR 549
    Length:549
    Mass (Da):61,622
    Last modified:November 2, 2001 - v2
    Checksum:iF65348C667068F16
    GO

    Sequence cautioni

    The sequence AAC23219.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC23219.1. Different initiation.
    PIRiF64130.
    RefSeqiNP_439722.2. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC23219; AAC23219; HI_1576.
    GeneIDi950436.
    KEGGihin:HI1576.
    PATRICi20191883. VBIHaeInf48452_1649.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC23219.1 . Different initiation.
    PIRi F64130.
    RefSeqi NP_439722.2. NC_000907.1.

    3D structure databases

    ProteinModelPortali P44312.
    SMRi P44312. Positions 23-549.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI1576.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC23219 ; AAC23219 ; HI_1576 .
    GeneIDi 950436.
    KEGGi hin:HI1576.
    PATRICi 20191883. VBIHaeInf48452_1649.

    Phylogenomic databases

    eggNOGi COG0166.
    KOi K01810.
    OMAi NCHFVAN.
    OrthoDBi EOG64R61J.
    PhylomeDBi P44312.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiG6PI_HAEIN
    AccessioniPrimary (citable) accession number: P44312
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 2, 2001
    Last modified: October 1, 2014
    This is version 93 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3