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P44157

- PGPA_HAEIN

UniProt

P44157 - PGPA_HAEIN

Protein

Phosphatidylglycerophosphatase A

Gene

pgpA

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).By similarity

    Catalytic activityi

    Phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.

    Cofactori

    Magnesium.By similarity

    Pathwayi

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphatidylglycerophosphatase activity Source: UniProtKB-EC

    GO - Biological processi

    1. phosphatidylglycerol biosynthetic process Source: UniProtKB-UniPathway
    2. phospholipid catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism

    Keywords - Ligandi

    Magnesium, Metal-binding

    Enzyme and pathway databases

    UniPathwayiUPA00084; UER00504.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphatidylglycerophosphatase A (EC:3.1.3.27)
    Alternative name(s):
    Phosphatidylglycerolphosphate phosphatase A
    Short name:
    PGP phosphatase A
    Gene namesi
    Name:pgpA
    Ordered Locus Names:HI_1306
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 163163Phosphatidylglycerophosphatase APRO_0000058360Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi71421.HI1306.

    Structurei

    3D structure databases

    ProteinModelPortaliP44157.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei10 – 2819HelicalSequence AnalysisAdd
    BLAST
    Transmembranei35 – 5117HelicalSequence AnalysisAdd
    BLAST
    Transmembranei92 – 11625HelicalSequence AnalysisAdd
    BLAST
    Transmembranei137 – 15721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1267.
    KOiK01095.
    OMAiYICDKAA.
    OrthoDBiEOG6P5ZM2.
    PhylomeDBiP44157.

    Family and domain databases

    InterProiIPR026037. PgpA.
    IPR007686. YutG/PgpA.
    [Graphical view]
    PfamiPF04608. PgpA. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006162. PgpA. 1 hit.
    SUPFAMiSSF101307. SSF101307. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P44157-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTENNPLKKI SLLNPIHLLA VGFGSGLIHP APGTWGSLAG TILGVILLSL    50
    LGVKIFLIFT ALCFLLGCYL CQKTTADMGV HDHGSIVWDE FVGVFIVLAA 100
    IPSLSWQWIL AAFALFRFFD ILKPFPIRYF DEKLENGFGI MIDDVLAAIY 150
    AVIVVFAIQY WML 163
    Length:163
    Mass (Da):18,035
    Last modified:November 1, 1995 - v1
    Checksum:i77CC4D4FC550937B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22953.1.
    PIRiD64025.
    RefSeqiNP_439457.1. NC_000907.1.
    WP_005694464.1. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC22953; AAC22953; HI_1306.
    GeneIDi950237.
    KEGGihin:HI1306.
    PATRICi20191295. VBIHaeInf48452_1358.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC22953.1 .
    PIRi D64025.
    RefSeqi NP_439457.1. NC_000907.1.
    WP_005694464.1. NC_000907.1.

    3D structure databases

    ProteinModelPortali P44157.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI1306.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC22953 ; AAC22953 ; HI_1306 .
    GeneIDi 950237.
    KEGGi hin:HI1306.
    PATRICi 20191295. VBIHaeInf48452_1358.

    Phylogenomic databases

    eggNOGi COG1267.
    KOi K01095.
    OMAi YICDKAA.
    OrthoDBi EOG6P5ZM2.
    PhylomeDBi P44157.

    Enzyme and pathway databases

    UniPathwayi UPA00084 ; UER00504 .

    Family and domain databases

    InterProi IPR026037. PgpA.
    IPR007686. YutG/PgpA.
    [Graphical view ]
    Pfami PF04608. PgpA. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006162. PgpA. 1 hit.
    SUPFAMi SSF101307. SSF101307. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiPGPA_HAEIN
    AccessioniPrimary (citable) accession number: P44157
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways

    External Data

    Dasty 3