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P44157

- PGPA_HAEIN

UniProt

P44157 - PGPA_HAEIN

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Protein

Phosphatidylglycerophosphatase A

Gene

pgpA

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).By similarity

Catalytic activityi

Phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.

Cofactori

Magnesium.By similarity

Pathwayi

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphatidylglycerophosphatase activity Source: UniProtKB-EC

GO - Biological processi

  1. phosphatidylglycerol biosynthetic process Source: UniProtKB-UniPathway
  2. phospholipid catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00084; UER00504.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidylglycerophosphatase A (EC:3.1.3.27)
Alternative name(s):
Phosphatidylglycerolphosphate phosphatase A
Short name:
PGP phosphatase A
Gene namesi
Name:pgpA
Ordered Locus Names:HI_1306
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 163163Phosphatidylglycerophosphatase APRO_0000058360Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi71421.HI1306.

Structurei

3D structure databases

ProteinModelPortaliP44157.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei10 – 2819HelicalSequence AnalysisAdd
BLAST
Transmembranei35 – 5117HelicalSequence AnalysisAdd
BLAST
Transmembranei92 – 11625HelicalSequence AnalysisAdd
BLAST
Transmembranei137 – 15721HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1267.
KOiK01095.
OMAiYICDKAA.
OrthoDBiEOG6P5ZM2.
PhylomeDBiP44157.

Family and domain databases

InterProiIPR026037. PgpA.
IPR007686. YutG/PgpA.
[Graphical view]
PfamiPF04608. PgpA. 1 hit.
[Graphical view]
PIRSFiPIRSF006162. PgpA. 1 hit.
SUPFAMiSSF101307. SSF101307. 1 hit.

Sequencei

Sequence statusi: Complete.

P44157-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTENNPLKKI SLLNPIHLLA VGFGSGLIHP APGTWGSLAG TILGVILLSL
60 70 80 90 100
LGVKIFLIFT ALCFLLGCYL CQKTTADMGV HDHGSIVWDE FVGVFIVLAA
110 120 130 140 150
IPSLSWQWIL AAFALFRFFD ILKPFPIRYF DEKLENGFGI MIDDVLAAIY
160
AVIVVFAIQY WML
Length:163
Mass (Da):18,035
Last modified:November 1, 1995 - v1
Checksum:i77CC4D4FC550937B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22953.1.
PIRiD64025.
RefSeqiNP_439457.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22953; AAC22953; HI_1306.
GeneIDi950237.
KEGGihin:HI1306.
PATRICi20191295. VBIHaeInf48452_1358.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC22953.1 .
PIRi D64025.
RefSeqi NP_439457.1. NC_000907.1.

3D structure databases

ProteinModelPortali P44157.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI1306.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC22953 ; AAC22953 ; HI_1306 .
GeneIDi 950237.
KEGGi hin:HI1306.
PATRICi 20191295. VBIHaeInf48452_1358.

Phylogenomic databases

eggNOGi COG1267.
KOi K01095.
OMAi YICDKAA.
OrthoDBi EOG6P5ZM2.
PhylomeDBi P44157.

Enzyme and pathway databases

UniPathwayi UPA00084 ; UER00504 .

Family and domain databases

InterProi IPR026037. PgpA.
IPR007686. YutG/PgpA.
[Graphical view ]
Pfami PF04608. PgpA. 1 hit.
[Graphical view ]
PIRSFi PIRSF006162. PgpA. 1 hit.
SUPFAMi SSF101307. SSF101307. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiPGPA_HAEIN
AccessioniPrimary (citable) accession number: P44157
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 29, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

External Data

Dasty 3