Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

3-oxo-tetronate kinase

Gene

otnK

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalyzes the ATP-dependent phosphorylation of 3-oxo-tetronate to 3-oxo-tetronate 4-phosphate.1 Publication

Catalytic activityi

ATP + 3-dehydro-L-erythronate = ADP + 3-dehydro-4-phospho-L-erythronate.1 Publication
ATP + 3-dehydro-D-erythronate = ADP + 3-dehydro-4-phospho-D-erythronate.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei254ATPBy similarity1
Binding sitei397ATP; via amide nitrogenBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi354 – 357ATPBy similarity4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processCarbohydrate metabolism
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHINF71421:G1GJ1-1051-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
3-oxo-tetronate kinase1 Publication (EC:2.7.1.2171 Publication)
Alternative name(s):
3-dehydrotetronate 4-kinaseCurated
Gene namesi
Name:otnK1 Publication
Ordered Locus Names:HI_1011
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001693141 – 4133-oxo-tetronate kinaseAdd BLAST413

Interactioni

Protein-protein interaction databases

STRINGi71421.HI1011

Structurei

Secondary structure

1413
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 8Combined sources6
Helixi9 – 20Combined sources12
Turni21 – 23Combined sources3
Beta strandi26 – 31Combined sources6
Beta strandi42 – 47Combined sources6
Beta strandi51 – 53Combined sources3
Helixi55 – 71Combined sources17
Beta strandi76 – 80Combined sources5
Helixi93 – 104Combined sources12
Beta strandi109 – 111Combined sources3
Helixi116 – 118Combined sources3
Beta strandi120 – 123Combined sources4
Beta strandi126 – 129Combined sources4
Helixi134 – 136Combined sources3
Helixi138 – 141Combined sources4
Beta strandi143 – 145Combined sources3
Helixi152 – 159Combined sources8
Beta strandi164 – 167Combined sources4
Helixi169 – 172Combined sources4
Helixi176 – 188Combined sources13
Beta strandi192 – 196Combined sources5
Beta strandi198 – 200Combined sources3
Helixi202 – 210Combined sources9
Turni211 – 213Combined sources3
Beta strandi215 – 220Combined sources6
Helixi221 – 232Combined sources12
Helixi237 – 239Combined sources3
Beta strandi248 – 252Combined sources5
Helixi257 – 266Combined sources10
Turni267 – 269Combined sources3
Beta strandi272 – 274Combined sources3
Helixi277 – 282Combined sources6
Helixi286 – 295Combined sources10
Turni296 – 299Combined sources4
Beta strandi300 – 302Combined sources3
Beta strandi305 – 307Combined sources3
Helixi312 – 319Combined sources8
Helixi324 – 345Combined sources22
Beta strandi349 – 354Combined sources6
Helixi355 – 365Combined sources11
Beta strandi369 – 377Combined sources9
Beta strandi380 – 389Combined sources10
Beta strandi391 – 395Combined sources5
Helixi404 – 410Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1YZYX-ray2.10A/B1-413[»]
ProteinModelPortaliP44093
SMRiP44093
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP44093

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105G63 Bacteria
COG3395 LUCA
KOiK21948
OMAiVYQGHLF
PhylomeDBiP44093

Family and domain databases

Gene3Di3.40.50.108401 hit
InterProiView protein in InterPro
IPR037051 4-carb_acid_sugar_kinase_N_sf
IPR010737 DUF1537
IPR031475 DUF1537_C
PfamiView protein in Pfam
PF17042 DUF1357_C, 1 hit
PF07005 DUF1537, 1 hit

Sequencei

Sequence statusi: Complete.

P44093-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGVIADDFT GASDIASFLV ENGLSTVQMN GVPTQSLNSK VDAIVISLKS
60 70 80 90 100
RSNPVNEAIE QSLRAYQWLK ENGCTQFYFK YCSTFDSTAK GNIGPVTDAL
110 120 130 140 150
LDELNEDFTV ITPALPVNGR TIFNGYLFVG DVLLSESGMK NHPITPMVDA
160 170 180 190 200
NLMRLMDAQA KGKTGLVAYA DVIKGASRVQ ECFAELKAQG YRYAVVDAVD
210 220 230 240 250
NSQLEVLAEA VADFKLVTGG SGLGAYMAAR LSGGKKGTNA FTPTKGKTVV
260 270 280 290 300
LSGSCSVMTN KQVEKYREKA PHFQLDVEQA IHNENYIEQL YQWVIANLDS
310 320 330 340 350
EFAPMVYATV PPDALKAIQH QFGVDQASHA IENTFAKLAA KLKQYGVTNF
360 370 380 390 400
ITAGGETSSI VVQELGFTGF HIGKQIAPGV PWLKAVEEDI FLALKSGNFG
410
KEDFFEYAQG MFL
Length:413
Mass (Da):44,787
Last modified:November 1, 1995 - v1
Checksum:i0639C8DA33D6A6D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA Translation: AAC22672.1
PIRiC64018
RefSeqiNP_439172.1, NC_000907.1
WP_005693348.1, NC_000907.1

Genome annotation databases

EnsemblBacteriaiAAC22672; AAC22672; HI_1011
GeneIDi950004
KEGGihin:HI1011
PATRICifig|71421.8.peg.1055

Similar proteinsi

Entry informationi

Entry nameiOTNK_HAEIN
AccessioniPrimary (citable) accession number: P44093
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 28, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome