P44088 (Y977_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable adenosine monophosphate-protein transferase HI_0977
EC=2.7.7.n1

Gene names

Ordered Locus Names:

HI_0977

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	191 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins By similarity.
Catalytic activity	ATP + [protein] = diphosphate + [protein]-AMP.
Sequence similarities	Belongs to the fic family. Contains 1 fido domain.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotidyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 191	191	Probable adenosine monophosphate-protein transferase HI_0977		PRO_0000077987
Regions
	Domain	37 – 162	126	Fido
	Nucleotide binding	67 – 68	2	ATP By similarity
	Nucleotide binding	112 – 114	3	ATP By similarity
Sites
	Binding site	118	1	ATP By similarity
	Binding site	145	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	P44088 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 5C327D09F6D2E93E	FASTA	191	22,541
	10 20 30 40 50 60 MPPKFWIIII VKKIDQQSLE NAYRLFESGD IHQIEIGSTK GLQQIHHYLF NGLYEFAGKI 70 80 90 100 110 120 REQNISKGHF RFANALYLKE ALGKIEQMPE DTFENIINKY VEMNIAHPFL EGNGRSTRIW 130 140 150 160 170 180 LDLVLKKHLG KVVNWQNVDK TQYLQAMERS PINDLEIRFL LQANLTDDVN NREIIFKGIE 190 QSYYYEGYEK E

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22637.1.
PIR	G64017.
RefSeq	NP_439140.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P44088.
SMR	P44088. Positions 11-187.
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI0977.
Protocols and materials databases
DNASU	949973.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC22637; AAC22637; HI_0977.
GeneID	949973.
KEGG	hin:HI0977.
PATRIC	20190615. VBIHaeInf48452_1020.
Phylogenomic databases
eggNOG	COG2184.
KO	K04095.
OMA	ERSPIND.
ProtClustDB	CLSK861839.
Family and domain databases
InterPro	IPR003812. Fido. [Graphical view]
Pfam	PF02661. Fic. 1 hit. [Graphical view]
SUPFAM	SSF140931. SSF140931. 1 hit.
PROSITE	PS51459. FIDO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y977_HAEIN

Accession

Primary (citable) accession number: P44088

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program