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Protein

Cell division protein FtsB

Gene

ftsB

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.UniRule annotation

GO - Biological processi

  1. FtsZ-dependent cytokinesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsBUniRule annotation
Gene namesi
Name:ftsBUniRule annotation
Ordered Locus Names:HI_0673
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

Cell inner membrane UniRule annotation; Single-pass type II membrane protein UniRule annotation
Note: Localizes to the division septum.UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 33CytoplasmicUniRule annotation
Transmembranei4 – 2118HelicalUniRule annotationAdd
BLAST
Topological domaini22 – 9271PeriplasmicUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. cell division site Source: UniProtKB-HAMAP
  2. integral component of plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9292Cell division protein FtsBPRO_0000214445Add
BLAST

Interactioni

Subunit structurei

Part of a complex composed of FtsB, FtsL and FtsQ.UniRule annotation

Protein-protein interaction databases

STRINGi71421.HI0673.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili28 – 6336UniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the FtsB family.UniRule annotation

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2919.
KOiK05589.
OMAiNGIHDYV.
OrthoDBiEOG6P5ZC4.
PhylomeDBiP44035.

Family and domain databases

HAMAPiMF_00599. FtsB.
InterProiIPR023081. Cell_div_FtsB.
IPR007060. FtsL/DivIC.
[Graphical view]
PfamiPF04977. DivIC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P44035-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRLLILILLS VLVLFQYNFW FGSNGFLDYR QNAEKIKENQ AENEKLSQRN
60 70 80 90
QRINAEIQGL TKGFEAIEER ARMQHGLVKE NEVFYHIVKE SK
Length:92
Mass (Da):10,916
Last modified:November 1, 1995 - v1
Checksum:iB30D25D34481F42B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22333.1.
PIRiH64011.
RefSeqiNP_438833.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22333; AAC22333; HI_0673.
GeneIDi950558.
KEGGihin:HI0673.
PATRICi20189963. VBIHaeInf48452_0703.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22333.1.
PIRiH64011.
RefSeqiNP_438833.1. NC_000907.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0673.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22333; AAC22333; HI_0673.
GeneIDi950558.
KEGGihin:HI0673.
PATRICi20189963. VBIHaeInf48452_0703.

Phylogenomic databases

eggNOGiCOG2919.
KOiK05589.
OMAiNGIHDYV.
OrthoDBiEOG6P5ZC4.
PhylomeDBiP44035.

Family and domain databases

HAMAPiMF_00599. FtsB.
InterProiIPR023081. Cell_div_FtsB.
IPR007060. FtsL/DivIC.
[Graphical view]
PfamiPF04977. DivIC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiFTSB_HAEIN
AccessioniPrimary (citable) accession number: P44035
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: January 7, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.