P44035 (FTSB_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cell division protein FtsB

Gene names

Name:	ftsB
Ordered Locus Names:	HI_0673

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	92 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic By similarity. HAMAP-Rule MF_00599
Subunit structure	Part of a complex composed of FtsB, FtsL and FtsQ By similarity.
Subcellular location	Cell inner membrane; Single-pass type II membrane protein By similarity. Note: Localizes to the division septum By similarity. HAMAP-Rule MF_00599
Sequence similarities	Belongs to the FtsB family.

Ontologies

Keywords
Biological process	Cell cycle Cell division
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Coiled coil Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cytokinesis by binary fission Inferred from electronic annotation. Source: HAMAP
Cellular_component	cell division site part Inferred from electronic annotation. Source: HAMAP integral to plasma membrane Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 92	92	Cell division protein FtsB HAMAP-Rule MF_00599		PRO_0000214445
Regions
	Topological domain	1 – 3	3	Cytoplasmic Potential
	Transmembrane	4 – 21	18	Helical; Potential
	Topological domain	22 – 92	71	Periplasmic Potential
	Coiled coil	28 – 63	36	Potential

Sequences

	Sequence		Length	Mass (Da)
	P44035 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: B30D25D34481F42B	FASTA	92	10,916
	10 20 30 40 50 60 MRLLILILLS VLVLFQYNFW FGSNGFLDYR QNAEKIKENQ AENEKLSQRN QRINAEIQGL 70 80 90 TKGFEAIEER ARMQHGLVKE NEVFYHIVKE SK

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22333.1.
PIR	H64011.
RefSeq	NP_438833.1. NC_000907.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI0673.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC22333; AAC22333; HI_0673.
GeneID	950558.
KEGG	hin:HI0673.
PATRIC	20189963. VBIHaeInf48452_0703.
Phylogenomic databases
eggNOG	COG2919.
KO	K05589.
OMA	YELGMVK.
ProtClustDB	PRK00888.
Family and domain databases
HAMAP	MF_00599. FtsB.
InterPro	IPR023081. Cell_div_FtsB. IPR007060. DivIC. [Graphical view]
Pfam	PF04977. DivIC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FTSB_HAEIN

Accession

Primary (citable) accession number: P44035

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program