Reviewed, UniProtKB/Swiss-Prot P43919 (GLND_HAEIN)

Names and origin

Protein names

Recommended name:
    [Protein-PII] uridylyltransferase
      Short name=PII uridylyl-transferase
    EC=2.7.7.59
Alternative name(s):
    Uridylyl-removing enzyme
    UTase

Gene names

Name:	glnD
Ordered Locus Names:	HI1719

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	863 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity.
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 863	863	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_0000192736

Sequences

	Sequence		Length	Mass (Da)
	P43919-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: B6F679A70A01A651	FASTA	863	100,173
	10 20 30 40 50 60 MLFSPTLSSL LTPSAVKIER ENLKQFELEN FSCYSIFELI ENRCDFYDAL LIQLWQEIGL 70 80 90 100 110 120 SEQQGISLIA VGGYGRREMF PLSDLDFLIL VEQTPSHEIE EKITQFIQFL WDCGFEVGNS 130 140 150 160 170 180 VRTLEQCELE GKQDITIATN LLEARFLTGN RPHFDVLNEL VKRADFWSKE DFFNAKVQEQ 190 200 210 220 230 240 IERYQRYHNT AYNLEPDIKF SPGGLRDLHL LYWVALRHSG ALTLEAILQS GFIYPQEYQQ 250 260 270 280 290 300 LQESRAFLFK VRFALHLILK RYDNRLLFDR QIKVSELLGF RGEGNPAVEK MMKCFFQALH 310 320 330 340 350 360 RISLISNLLI QHYRENVLSS NQDTVIDQLD DDFQLINQSL CLRNSFVFQE KPARILDLFF 370 380 390 400 410 420 YLTQYEHVNI HSDTLRQLQI SLEQLSQKLC EIPAAREKFL RLFNQSNAIK RAFMPMHQYG 430 440 450 460 470 480 VLTAYLPQWQ AIEGLMQFDL FHIYTVDEHT LRVMLKLESF LPKGSAQEHP IAHRIFSQLS 490 500 510 520 530 540 DRTLLYIAAL FHDIAKGRGG DHAELGAEDV ADFAQLHGLD RREIDTLAWL VQSHLLMSIT 550 560 570 580 590 600 AQRRDIHDPE VVMNFAEAMQ NQVRLDYLTC LTVADICATN GNLWNSWKRS LFASLYEFTE 610 620 630 640 650 660 QQFSQGMKEL LDYSEKSAEN RKLAQQILTQ DYSDITSISI EKLWTRCPED YFVRNTPKQI 670 680 690 700 710 720 AWHTSLLVDF VEALLVKISN RFSLGGTEVF IYCQDQPHLF NKVVSTIGAK KFSIHDAQII 730 740 750 760 770 780 TTQDGYVFDS FIITELNGEL VEFDRRRELE QALTVALQSE KLPALSIVPN RQLQHFTVQT 790 800 810 820 830 840 DVRFLQENKK EHTEMELVAL DKAGLLAQVS QIFTELNLNL LNAKITTVGE KAEDFFILTN 850 860 QFGQALAREE RERLNSVIIQ QIR

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L42023 Genomic DNA. Translation: AAC23362.1.
PIR	B64138.
RefSeq	NP_439860.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	950533.
GenomeReviews	Gene locus HI1719 in contig L42023_GR.
KEGG	hin:HI1719.
NMPDR	fig|71421.1.peg.1631.
TIGR	HI1719.
Phylogenomic databases
HOGENOM	P43919.
OMA	MQHDLFH.
Enzyme and pathway databases
BioCyc	HINF71421:HI_1719-MON.
BRENDA	2.7.7.59. 109.
Family and domain databases
HAMAP	MF_00277. [Tree]
InterPro	IPR002912. ACT_bd. IPR010043. GlnD_Uridyltrans. IPR003607. Met-dep_phosphohydro_HD. IPR006674. Met-dep_phosphohydro_HD_sub. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_HAEIN

Accession

Primary (citable) accession number: P43919

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 3, 2009
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)