Skip Header

Contribute Send feedback
Read comments (?) or add your own

P43879 (AROB_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:HI_0208
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

NAD By similarity. HAMAP MF_00110

Divalent metal cations By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3623623-dehydroquinate synthase HAMAP MF_00110
PRO_0000140743

Sequences

Sequence LengthMass (Da)Tools
P43879 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: F787324C1428A110

FASTA36239,919
        10         20         30         40         50         60 
MLCVNVELQE RRYPILIGSG LLQDERSYPI KRGDRVMIVT NPTVAQFYLD TVIYALEKRG 

        70         80         90        100        110        120 
CVVDHVLLPD GEKYKTLESL NLIFTALLQG NHGRDTTIIA LGGGVIGDVA GFAAASYQRG 

       130        140        150        160        170        180 
VRLIQIPTTL LSQVDSSVGG KTAVNHELGK NMIGAFYQPS MVIIDTLTLN TLPKREVNAG 

       190        200        210        220        230        240 
LAEVIKYGAI LDYEFFEWLE QHIDELVALH PEALQHCISR CCQIKADVVA RDETEKGDRA 

       250        260        270        280        290        300 
LLNLGHTFGH AIETHLGYGN WLHGEAVSTG MMMAAALSEE LGDISIADVS RLEKLLARAN 

       310        320        330        340        350        360 
LPTVSPDTMQ PEDYLPHMMR DKKVLSGKLR LVLLKSLGQA YVANDTEHTL VLNAIRRCTQ 


TD

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L42023 Genomic DNA. Translation: AAC21876.1.
PIRG64054.
RefSeqNP_438377.1. NC_000907.1.

3D structure databases

ProteinModelPortalP43879.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID951118.
GenomeReviewsGene locus HI_0208 in contig L42023_GR.
KEGGhin:HI0208.
NMPDRfig|71421.1.peg.198.
PATRIC20188913. VBIHaeInf48452_0213.
TIGRHI_0208.

Phylogenomic databases

HOGENOMHBG632303.
OMALGQSDFT.
PhylomeDBP43879.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycHINF71421:HI_0208-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_HAEIN
AccessionPrimary (citable) accession number: P43879
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: January 25, 2012
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents