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P43870 (T2D3_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type-2 restriction enzyme HindIII

Short name=R.HindIII
EC=3.1.21.4
Alternative name(s):
Endonuclease HindIII
Type II restriction enzyme HindIII
Gene names
Name:hindIIIR
Ordered Locus Names:HI_1393
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length300 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Recognizes the double-stranded sequence AAGCTT and cleaves after A-1.

Catalytic activity

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 300300Type-2 restriction enzyme HindIII
PRO_0000077321

Secondary structure

............................................... 300
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P43870 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 62F62AC4B18E841B

FASTA30034,952
        10         20         30         40         50         60 
MKKSALEKLL SLIENLTNQE FKQATNSLIS FIYKLNRNEV IELVRSIGIL PEAIKPSSTQ 

        70         80         90        100        110        120 
EKLFSKAGDI VLAKAFQLLN LNSKPLEQRG NAGDVIALSK EFNYGLVADA KSFRLSRTAK 

       130        140        150        160        170        180 
NQKDFKVKAL SEWREDKDYA VLTAPFFQYP TTKSQIFKQS LDENVLLFSW EHLAILLQLD 

       190        200        210        220        230        240 
LEETNIFSFE QLWNFPKKQS KKTSVSDAEN NFMRDFNKYF MDLFKIDKDT LNQLLQKEIN 

       250        260        270        280        290        300 
FIEERSLIEK EYWKKQINII KNFTREEAIE ALLKDINMSS KIETIDSFIK GIKSNDRLYL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L15391 Genomic DNA. Translation: AAA61958.1.
L42023 Genomic DNA. Translation: AAC23040.1.
PIRH64121.
RefSeqNP_439547.1. NC_000907.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2E52X-ray2.00A/B/C/D1-300[»]
3A4KX-ray2.17A/B/C/D1-300[»]
ProteinModelPortalP43870.
SMRP43870. Positions 2-300.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI1393.

Chemistry

BindingDBP43870.
ChEMBLCHEMBL5004.

Protein family/group databases

REBASE1151. HindIII.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC23040; AAC23040; HI_1393.
GeneID950303.
KEGGhin:HI1393.
PATRIC20191483. VBIHaeInf48452_1452.

Phylogenomic databases

eggNOGNOG45031.
KOK01155.
OMADINMSSK.
OrthoDBEOG686NN8.

Family and domain databases

InterProIPR019043. Restrct_endonuc_II_HindIII.
[Graphical view]
PfamPF09518. RE_HindIII. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP43870.

Entry information

Entry nameT2D3_HAEIN
AccessionPrimary (citable) accession number: P43870
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 14, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Restriction enzymes and methylases

Classification of restriction enzymes and methylases and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names