P43840 (OMP51_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Outer membrane protein P5
Short name=OMP P5

Gene names

Name:	ompA
Synonyms:	ompP5
Ordered Locus Names:	HI_1164

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	353 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell outer membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the OmpA family. Contains 1 OmpA-like domain.

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal Transmembrane Transmembrane beta strand
Molecular function	Porin
PTM	Disulfide bond
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ion transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW pore complex Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	porin activity Inferred from electronic annotation. Source: UniProtKB-KW structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	By similarity
	Chain	22 – 353	332	Outer membrane protein P5		PRO_0000020107
Regions
	Domain	227 – 353	127	OmpA-like
Amino acid modifications
	Disulfide bond	326 ↔ 338		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P43840 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 64ACB3E7BFF96B39	FASTA	353	37,744
	10 20 30 40 50 60 MKKTAIALVV AGLAAASVAQ AAPQENTFYA GVKAGQASFH DGLRALAREY KVGYHRNSFT 70 80 90 100 110 120 YGVFGGYQIL NQNNLGLAVE LGYDDFGRAK GREKGKTVVK HTNHGTHLSL KGSYEVLEGL 130 140 150 160 170 180 DVYGKAGVAL VRSDYKLYNE NSSTLKKLGE HHRARASGLF AVGAEYAVLP ELAVRLEYQW 190 200 210 220 230 240 LTRVGKYRPQ DKPNTALNYN PWIGSINAGI SYRFGQGAAP VVAAPEVVSK TFSLNSDVTF 250 260 270 280 290 300 AFGKANLKPQ AQATLDSIYG EMSQVKSAKV AVAGYTDRIG SDAFNVKLSQ ERADSVANYF 310 320 330 340 350 VAKGVAADAI SATGYGKANP VTGATCDQVK GRKALIACFA PDRRVEIAVN GTK

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22819.1.
PIR	C64187.
RefSeq	NP_439322.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P43840.
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI1164.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC22819; AAC22819; HI_1164.
GeneID	950124.
KEGG	hin:HI1164.
PATRIC	20191007. VBIHaeInf48452_1216.
Phylogenomic databases
eggNOG	COG2885.
KO	K03286.
OMA	DDNEAQK.
ProtClustDB	CLSK808491.
Family and domain databases
Gene3D	2.40.160.20. 1 hit. 3.30.1330.60. 1 hit.
InterPro	IPR011250. OMP/PagP_b-brl. IPR006664. OMP_bac. IPR002368. OmpA. IPR006690. OMPA-like_CS. IPR000498. OmpA-like_TM_dom. IPR006665. OmpA/MotB_C. [Graphical view]
Pfam	PF00691. OmpA. 1 hit. PF01389. OmpA_membrane. 1 hit. [Graphical view]
PRINTS	PR01021. OMPADOMAIN. PR01022. OUTRMMBRANEA.
SUPFAM	SSF103088. OmpA/MotB_C. 1 hit. SSF56925. SSF56925. 1 hit.
PROSITE	PS01068. OMPA_1. 1 hit. PS51123. OMPA_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

OMP51_HAEIN

Accession

Primary (citable) accession number: P43840

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 90 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program