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P43831

- SYQ_HAEIN

UniProt

P43831 - SYQ_HAEIN

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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei280 – 2801ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glutamine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutaminyl-tRNA aminoacylation Source: InterPro
  2. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligase (EC:6.1.1.18)
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name:
GlnRS
Gene namesi
Name:glnS
Ordered Locus Names:HI_1354
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 557557Glutamine--tRNA ligasePRO_0000195837Add
BLAST

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi71421.HI1354.

Structurei

3D structure databases

ProteinModelPortaliP43831.
SMRiP43831. Positions 18-555.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi42 – 5211"HIGH" regionAdd
BLAST
Motifi277 – 2815"KMSKS" region

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0008.
KOiK01886.
OMAiSREIYID.
OrthoDBiEOG6DRPF7.
PhylomeDBiP43831.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P43831-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMSHTETSLG AENTRTHNFI TQIIDEDLAS GKHKSVHTRF PPEPNGYLHI
60 70 80 90 100
GHAKSICLNF GLAKEYQGLC NLRFDDTNPV KEDVEYVDSI KADVEWLGFK
110 120 130 140 150
WEGEPRYASD YFDALYGYAV ELIKKGLAYV DELSPDEMRE YRGTLTEPGK
160 170 180 190 200
NSPYRDRTIE ENLALFEKMK NGEFAEGKAS LRAKIDMASP FMVMREPVIY
210 220 230 240 250
RIKFSSHHQT GDKWCIYPMY DFTHCISDAI ERITHSICTL EFQDNRRLYD
260 270 280 290 300
WVLENISIER PLPHQYEFSR LNLEGTLTSK RKLLKLVNDE IVDGWNDPRM
310 320 330 340 350
PTISGLRRRG YTPASLREFC RRIGVTKQDN VVEYSALEAC IREDLNENAP
360 370 380 390 400
RAMAVIDPVR VVIENFESEA VLTAPNHPNR PELGERQLPF TKELYIDRAD
410 420 430 440 450
FREEANKQYK RLVLGKEVRL RNAYVIKAER VEKDANGEIT TIFCTYDPET
460 470 480 490 500
LGKNPADGRK VKGVIHWVSA VNNHPAEFRL YDRLFTVPNP GAEDDIESVL
510 520 530 540 550
NPNSLVIKQG FVEQSLANAE AEKGYQFERE GYFCADSKDS RPEHLVFNLT

VSLKEGF
Length:557
Mass (Da):64,078
Last modified:November 1, 1995 - v1
Checksum:i4FF1452D57A29F72
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC23001.1.
PIRiG64118.
RefSeqiNP_439505.1. NC_000907.1.
WP_010869190.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC23001; AAC23001; HI_1354.
GeneIDi950274.
KEGGihin:HI1354.
PATRICi20191393. VBIHaeInf48452_1407.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC23001.1 .
PIRi G64118.
RefSeqi NP_439505.1. NC_000907.1.
WP_010869190.1. NC_000907.1.

3D structure databases

ProteinModelPortali P43831.
SMRi P43831. Positions 18-555.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI1354.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC23001 ; AAC23001 ; HI_1354 .
GeneIDi 950274.
KEGGi hin:HI1354.
PATRICi 20191393. VBIHaeInf48452_1407.

Phylogenomic databases

eggNOGi COG0008.
KOi K01886.
OMAi SREIYID.
OrthoDBi EOG6DRPF7.
PhylomeDBi P43831.

Family and domain databases

Gene3Di 1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPi MF_00126. Gln_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF50715. SSF50715. 1 hit.
TIGRFAMsi TIGR00440. glnS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiSYQ_HAEIN
AccessioniPrimary (citable) accession number: P43831
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 29, 2014
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3