Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei75L-glutamineUniRule annotation1
Binding sitei220L-glutamineUniRule annotation1
Binding sitei239ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi43 – 45ATPUniRule annotation3
Nucleotide bindingi49 – 55ATPUniRule annotation7
Nucleotide bindingi270 – 271ATPUniRule annotation2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:HI_1354
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001958371 – 557Glutamine--tRNA ligaseAdd BLAST557

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi71421.HI1354.

Structurei

3D structure databases

ProteinModelPortaliP43831.
SMRiP43831.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi42 – 52"HIGH" regionUniRule annotationAdd BLAST11
Motifi277 – 281"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotationCurated

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
KOiK01886.
OMAiVTHSICT.
PhylomeDBiP43831.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 3 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

P43831-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSHTETSLG AENTRTHNFI TQIIDEDLAS GKHKSVHTRF PPEPNGYLHI
60 70 80 90 100
GHAKSICLNF GLAKEYQGLC NLRFDDTNPV KEDVEYVDSI KADVEWLGFK
110 120 130 140 150
WEGEPRYASD YFDALYGYAV ELIKKGLAYV DELSPDEMRE YRGTLTEPGK
160 170 180 190 200
NSPYRDRTIE ENLALFEKMK NGEFAEGKAS LRAKIDMASP FMVMREPVIY
210 220 230 240 250
RIKFSSHHQT GDKWCIYPMY DFTHCISDAI ERITHSICTL EFQDNRRLYD
260 270 280 290 300
WVLENISIER PLPHQYEFSR LNLEGTLTSK RKLLKLVNDE IVDGWNDPRM
310 320 330 340 350
PTISGLRRRG YTPASLREFC RRIGVTKQDN VVEYSALEAC IREDLNENAP
360 370 380 390 400
RAMAVIDPVR VVIENFESEA VLTAPNHPNR PELGERQLPF TKELYIDRAD
410 420 430 440 450
FREEANKQYK RLVLGKEVRL RNAYVIKAER VEKDANGEIT TIFCTYDPET
460 470 480 490 500
LGKNPADGRK VKGVIHWVSA VNNHPAEFRL YDRLFTVPNP GAEDDIESVL
510 520 530 540 550
NPNSLVIKQG FVEQSLANAE AEKGYQFERE GYFCADSKDS RPEHLVFNLT

VSLKEGF
Length:557
Mass (Da):64,078
Last modified:November 1, 1995 - v1
Checksum:i4FF1452D57A29F72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC23001.1.
PIRiG64118.
RefSeqiNP_439505.1. NC_000907.1.
WP_010869190.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC23001; AAC23001; HI_1354.
GeneIDi950274.
KEGGihin:HI1354.
PATRICifig|71421.8.peg.1407.

Similar proteinsi

Entry informationi

Entry nameiSYQ_HAEIN
AccessioniPrimary (citable) accession number: P43831
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: August 30, 2017
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families