Reviewed, UniProtKB/Swiss-Prot P43800 (GLPB_HAEIN)

Names and origin

Protein names

Recommended name:
    Anaerobic glycerol-3-phosphate dehydrogenase subunit B
      Short name=Anaerobic G-3-P dehydrogenase subunit B
      Short name=Anaerobic G3Pdhase B
    EC=1.1.5.3

Gene names

Name:	glpB
Ordered Locus Names:	HI0684

Organism

Haemophilus influenzae [Complete proteome] [HAMAP]

Taxonomic identifier

727 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	432 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity.
Catalytic activity	sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP MF_00753
Cofactor	FMN By similarity.
Pathway	Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP MF_00753
Subunit structure	Composed of a catalytic glpA/B dimer and of membrane bound glpC By similarity.
Sequence similarities	Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
Ligand	FMN Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro glycerol-3-phosphate dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 432	432	Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP MF_00753		PRO_0000204563

Sequences

	Sequence		Length	Mass (Da)
	P43800-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 6D99EEAC75549228	FASTA	432	47,251
	10 20 30 40 50 60 MNFDVAIIGG GLAGLTCAIA LQQRGKRCVI INNGQAAIDF ASGSLDLLSR MPSTTYGENR 70 80 90 100 110 120 AVENLKENIT ALRNELPAHP YSLLGAEKVL AKAQDFERLA NELHLDLIGS TEKNHWRVTG 130 140 150 160 170 180 LGSLRGAWLS PNSVPTVQGN EPFPHKRIAV LGIEGYHDFQ PQLLAANLVL NPQFEHCEVT 190 200 210 220 230 240 SGFLNIPQLD ELRKNAREFR SVNISQLLEH KLAFKDLVKE IIESAQGAEA VFLPACFGLE 250 260 270 280 290 300 NQEFMTALRD ATKLALFELP TLPPSLLGMR QRIQLRHKFE SLGGLMINGD SALNATFEGN 310 320 330 340 350 360 QVRCINTRLL EDEEITADNF VLASGSFFSK GLISEFDKIY EPVFESDIIG VEGFNNKDRF 370 380 390 400 410 420 TWTAHRFAHP QPYQSAGVAI NAQCQVKKCG QFLTNLYAVG NVIGGFNALE LGCGSGVAVV 430 TALAVADEIL AK

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L42023 Genomic DNA. Translation: AAC22344.1.
RefSeq	NP_438844.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	950690.
GenomeReviews	Gene locus HI0684 in contig L42023_GR.
KEGG	hin:HI0684.
NMPDR	fig|71421.1.peg.654.
TIGR	HI0684.
Phylogenomic databases
HOGENOM	P43800.
OMA	P43800. TWLSQPF.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0684-MON.
BRENDA	1.1.99.5. 109.
Family and domain databases
HAMAP	MF_00753. [Tree]
InterPro	IPR009158. Anaerobic_glycerol3P_DH_bsu. IPR003953. FAD_bind2_N. [Graphical view]
Pfam	PF00890. FAD_binding_2. 1 hit. [Graphical view]
PIRSF	PIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMs	TIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLPB_HAEIN

Accession

Primary (citable) accession number: P43800

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	June 16, 2009
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)