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P43799 (GLPA_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Anaerobic glycerol-3-phosphate dehydrogenase subunit A

Short name=G-3-P dehydrogenase
EC=1.1.5.3
Gene names
Name:glpA
Ordered Locus Names:HI_0685
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length563 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactor

FAD By similarity.

FMN By similarity.

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1.

Subunit structure

Composed of a catalytic GlpA/B dimer and of membrane bound GlpC By similarity.

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity. Note: Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase By similarity.

Sequence similarities

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 563563Anaerobic glycerol-3-phosphate dehydrogenase subunit A
PRO_0000126095

Regions

Nucleotide binding20 – 4829FAD Potential

Sequences

Sequence LengthMass (Da)Tools
P43799 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 7E662A80F4E1EED6

FASTA56361,920
        10         20         30         40         50         60 
MGLSPSIYKD VGDLSSLSTD VIIIGGGATG AGIARDCALR GIDCILLERR DIATGATGRN 

        70         80         90        100        110        120 
HGLLHSGARY AVNDQESAEE CIKENRILRK IARHCVDETE GLFITLPEDS LDYQKTFLES 

       130        140        150        160        170        180 
CAKSGIDAQA IDPELAKIME PSVNPDLVGA VVVPDGSIDP FRLTASNMMD ATENGAKMFT 

       190        200        210        220        230        240 
YCEVKNLIRE GGKVIGVNAY DHKNRRERQF FAPLVVNAGG IWGQGIAEYA DLKIKMFPAK 

       250        260        270        280        290        300 
GALLVMGHRI NKLVINRCRK PADADILVPG DTICVIGTTS SRIPYDQIDN MEVTPEEVDI 

       310        320        330        340        350        360 
LFREGEKLAP SLRHTRVLRA YAGVRPLVAS DDDPSGRNVS RGIVLLDHAE RDGLDGFITI 

       370        380        390        400        410        420 
TGGKLMTYRL MAEWATDLVC KKLNKTARCV TAEQPLPGST ESRQETNQKV ISLPSTIRYS 

       430        440        450        460        470        480 
AVYRHGSRAT RLLEKERLDR SMVCECEAVT AGEVRYAVDE LDVNNLVDLR RRSRVGMGTC 

       490        500        510        520        530        540 
QAELCACRAA GLMNRFEVAT PRQSTTQLSA FMEERWRGIE PIAWGEAIRE AEFTSWMYAS 

       550        560 
VLGLNDVKPL DEQAQQGTDS NEF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L42023 Genomic DNA. Translation: AAC22345.1.
PIRE64086.
RefSeqNP_438845.1. NC_000907.1.

3D structure databases

ProteinModelPortalP43799.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING71421.HI0685.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC22345; AAC22345; HI_0685.
GeneID949605.
KEGGhin:HI0685.
PATRIC20189989. VBIHaeInf48452_0716.

Phylogenomic databases

eggNOGCOG0578.
KOK00111.
OMAQIDNMEV.
OrthoDBEOG651SR7.
ProtClustDBPRK11101.

Enzyme and pathway databases

UniPathwayUPA00618; UER00673.

Family and domain databases

InterProIPR007419. BFD-like_2Fe2S-bd_dom.
IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
IPR017752. G3P_DH_GlpA_su.
[Graphical view]
PfamPF01266. DAO. 1 hit.
PF04324. Fer2_BFD. 1 hit.
[Graphical view]
PRINTSPR01001. FADG3PDH.
TIGRFAMsTIGR03377. glycerol3P_GlpA. 1 hit.
PROSITEPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLPA_HAEIN
AccessionPrimary (citable) accession number: P43799
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 13, 2013
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names