Skip Header

 
Contribute Send feedback

Reviewed, UniProtKB/Swiss-Prot P43773 (HSLU_HAEIN)

Last modified July 22, 2008. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    ATP-dependent hsl protease ATP-binding subunit hslU
Gene names
Name: hslU
Ordered Locus Names: HI0497
OrganismHaemophilus influenzae [Complete proteome] [HAMAP]
Taxonomic identifier727 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Hide | Top

Protein attributes

Sequence length444 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

Hide | Top

General annotation (Comments)

Function

Chaperone subunit of a proteasome-like degradation complex.

Subunit structure

A double ring-shaped homohexamer of hslV is capped on each side by a ring-shaped hslU homohexamer.

Subcellular location

CytoplasmBy similarity.

Sequence similarities

Belongs to the clpX chaperone family. HslU subfamily.

Hide | Top

Ontologies

Keywords

   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionChaperone
   Technical term3D-structure
Complete proteome

Gene Ontology (GO)

   UncategorizedHslUV protease activity

Inferred from electronic annotation. Source: HAMAP

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical view

Molecule processing

Chain1 – 444444ATP-dependent hsl protease ATP-binding subunit hslU

Regions

Nucleotide binding57 – 648ATP

Secondary structure

1 ........................................................... 444
Helix Strand Turn

Details...

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
P43773-1 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: C346EA478E4094CE

FASTA44449,372
        10         20         30         40         50         60 
MSEMTPREIV SELDQHIIGQ ADAKRAVAIA LRNRWRRMQL QEPLRHEVTP KNILMIGPTG 

        70         80         90        100        110        120 
VGKTEIARRL AKLANAPFIK VEATKFTEVG YVGKEVDSII RDLTDSAMKL VRQQEIAKNR 

       130        140        150        160        170        180 
ARAEDVAEER ILDALLPPAK NQWGEVENHD SHSSTRQAFR KKLREGQLDD KEIEIDVSAG 

       190        200        210        220        230        240 
VSMGVEIMAP PGMEEMTNQL QSLFQNLGSD KTKKRKMKIK DALKALIDDE AAKLINPEEL 

       250        260        270        280        290        300 
KQKAIDAVEQ NGIVFIDEID KICKKGEYSG ADVSREGVQR DLLPLVEGST VSTKHGMVKT 

       310        320        330        340        350        360 
DHILFIASGA FQVARPSDLI PELQGRLPIR VELTALSAAD FERILTEPHA SLTEQYKALM 

       370        380        390        400        410        420 
ATEGVNIAFT TDAVKKIAEA AFRVNEKTEN IGARRLHTVM ERLMDKISFS ASDMNGQTVN 

       430        440 
IDAAYVADAL GEVVENEDLS RFIL

« Hide

Hide | Top

Cross-references

Sequence databases

L42023 Genomic DNA. Translation: AAC22154.1.
RefSeqNP_438655.1.

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
1G3IX-ray3.41A/B/C/D/E/F/S/T/U/V/W/X1-444[»]
1G41X-ray2.30A1-444[»]
1IM2X-ray2.80A1-444[»]
1KYIX-ray3.10A/B/C/D/E/F/S/T/U/V/W/X1-444[»]
1OFHX-ray2.50A/B/C149-444[»]
1OFIX-ray3.20A/B/C149-444[»]
ModBaseSearch...

Protein-protein interaction databases

DIPDIP:6175N.
IntActP43773.

Genome annotation databases

GeneID950614.
GenomeReviewsGene locus HI0497 in contig L42023_GR.
KEGGhin:HI0497.
NMPDRfig|71421.1.peg.468.
TIGRHI0497.

Phylogenomic databases

HOGENOMP43773.

Enzyme and pathway databases

BioCycHINF71421:HI_0497-MON.

Family and domain databases

HAMAPMF_00249.
[Tree]
InterProIPR003593. AAA+_ATPase_core.
IPR013093. ATPase_AAA-2.
IPR004491. HslU.
[Graphical view]
PANTHERPTHR11262:SF3. HslU. 1 hit.
PfamPF07724. AAA_2. 2 hits.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00390. hslU. 1 hit.
ProDomP43773.
[Graphical view] [Entries sharing at least one domain]
BLOCKSSearch...

Other Resources

LinkHubP43773.
ProtoNetSearch...

Hide | Top

Entry information

Entry nameHSLU_HAEIN
AccessionPrimary (citable) accession number: P43773
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 22, 2008
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Hide | Top

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents