Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P43770

- UDP_HAEIN

UniProt

P43770 - UDP_HAEIN

Protein

Uridine phosphorylase

Gene

udp

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 97 (01 Oct 2014)
      Sequence version 2 (03 Oct 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis By similarity.By similarity

    Catalytic activityi

    Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.

    Pathwayi

    GO - Molecular functioni

    1. uridine phosphorylase activity Source: UniProtKB-EC

    GO - Biological processi

    1. nucleotide catabolic process Source: InterPro
    2. UMP salvage Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Enzyme and pathway databases

    UniPathwayiUPA00574; UER00633.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uridine phosphorylase (EC:2.4.2.3)
    Short name:
    UPase
    Short name:
    UrdPase
    Gene namesi
    Name:udp
    Ordered Locus Names:HI_0280
    OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
    Taxonomic identifieri71421 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000000579: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 252252Uridine phosphorylasePRO_0000063186Add
    BLAST

    Interactioni

    Subunit structurei

    Homohexamer.By similarity

    Protein-protein interaction databases

    STRINGi71421.HI0280.

    Structurei

    3D structure databases

    ProteinModelPortaliP43770.
    SMRiP43770. Positions 2-251.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PNP/UDP phosphorylase family.Curated

    Phylogenomic databases

    eggNOGiCOG2820.
    KOiK00757.
    OMAiHIACKPG.
    OrthoDBiEOG676Z3T.
    PhylomeDBiP43770.

    Family and domain databases

    Gene3Di3.40.50.1580. 1 hit.
    InterProiIPR018017. Nucleoside_phosphorylase.
    IPR018016. Nucleoside_phosphorylase_CS.
    IPR000845. Nucleoside_phosphorylase_d.
    IPR010058. Uridine_phosphorylase.
    [Graphical view]
    PANTHERiPTHR21234. PTHR21234. 1 hit.
    PfamiPF01048. PNP_UDP_1. 1 hit.
    [Graphical view]
    SUPFAMiSSF53167. SSF53167. 1 hit.
    TIGRFAMsiTIGR01718. Uridine-psphlse. 1 hit.
    PROSITEiPS01232. PNP_UDP_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P43770-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSGVFHLNLT KAQLKGATLA IVPGDPARSE RIAKQLDNPE FLTSTREFTS    50
    WLGYINGQPI VVCSTGIGGP STSICVEELA QLGVRTFLRI GTTGAIQPHI 100
    NVGDVLITTA AVRLDGASHH FVPLEYPAVA NFECTTALYN AAKAKGIEPY 150
    VGVTVSSDTF YPGQERYDTY SGKVYRNYQG LLKQWQDLNV MNYEMESSTL 200
    FTMCSALGLR AGMVAGVIVN RTQQEIPNEA TIKQTEEKAV SVVITAAQAL 250
    LS 252
    Length:252
    Mass (Da):27,254
    Last modified:October 3, 2003 - v2
    Checksum:i30A007A6A764DEF6
    GO

    Sequence cautioni

    The sequence AAC21943.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC21943.1. Different initiation.
    PIRiC64059.
    RefSeqiNP_438448.2. NC_000907.1.

    Genome annotation databases

    EnsemblBacteriaiAAC21943; AAC21943; HI_0280.
    GeneIDi950640.
    KEGGihin:HI0280.
    PATRICi20189099. VBIHaeInf48452_0296.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L42023 Genomic DNA. Translation: AAC21943.1 . Different initiation.
    PIRi C64059.
    RefSeqi NP_438448.2. NC_000907.1.

    3D structure databases

    ProteinModelPortali P43770.
    SMRi P43770. Positions 2-251.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 71421.HI0280.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC21943 ; AAC21943 ; HI_0280 .
    GeneIDi 950640.
    KEGGi hin:HI0280.
    PATRICi 20189099. VBIHaeInf48452_0296.

    Phylogenomic databases

    eggNOGi COG2820.
    KOi K00757.
    OMAi HIACKPG.
    OrthoDBi EOG676Z3T.
    PhylomeDBi P43770.

    Enzyme and pathway databases

    UniPathwayi UPA00574 ; UER00633 .

    Family and domain databases

    Gene3Di 3.40.50.1580. 1 hit.
    InterProi IPR018017. Nucleoside_phosphorylase.
    IPR018016. Nucleoside_phosphorylase_CS.
    IPR000845. Nucleoside_phosphorylase_d.
    IPR010058. Uridine_phosphorylase.
    [Graphical view ]
    PANTHERi PTHR21234. PTHR21234. 1 hit.
    Pfami PF01048. PNP_UDP_1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53167. SSF53167. 1 hit.
    TIGRFAMsi TIGR01718. Uridine-psphlse. 1 hit.
    PROSITEi PS01232. PNP_UDP_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

    Entry informationi

    Entry nameiUDP_HAEIN
    AccessioniPrimary (citable) accession number: P43770
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: October 3, 2003
    Last modified: October 1, 2014
    This is version 97 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Haemophilus influenzae
      Haemophilus influenzae (strain Rd): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3