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P43739 (RPOC_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit beta'
Short name=RNAP subunit beta'
EC=2.7.7.6
Alternative name(s):
RNA polymerase subunit beta'
Transcriptase subunit beta'
Gene names
Name:rpoC
Ordered Locus Names:HI_0514
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length1415 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. HAMAP MF_01322

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_01322

Subunit structure

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Ontologies

Keywords
   Biological processTranscription
   Cellular componentDNA-directed RNA polymerase
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular functionDNA binding

Inferred from electronic annotation. Source: InterPro

DNA-directed RNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 14151415DNA-directed RNA polymerase subunit beta' HAMAP MF_01322
PRO_0000067747

Sequences

Sequence LengthMass (Da)Tools
P43739 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 09FA68FACB49A40B

FASTA1,415157,210
        10         20         30         40         50         60 
MKDLVKFLKA QSKTSEDFDV IKIGLASPDM IRSWSFGEVK KPETINYRTF KPERDGLFCA 

        70         80         90        100        110        120 
RIFGPVKDYE CLCGKYKRLK HRGVICEKCG VEVTQTKVRR ERMGHIELAS PVAHIWFLKS 

       130        140        150        160        170        180 
LPSRIGLLLD MPLRDIERVL YFEMYIVTEP GMTDLERGQL LTEEQYLDAE DRWQDEFEAK 

       190        200        210        220        230        240 
MGAEAIQDLL KGMDLEAECE KLREELQETN SETKRKKITK RLKLLEAFVQ SGNKPEWMVM 

       250        260        270        280        290        300 
TVLPVLPPDL RPLVPLDGGR FATSDLNDLY RRVINRNNRL KRLLDLIAPD IIVRNEKRML 

       310        320        330        340        350        360 
QESVDALLDN GRRGRAITGS NRRPLKSLAD MIKGKQGRFR QNLLGKRVDY SGRSVITVGP 

       370        380        390        400        410        420 
YLHLHQCGLP KKMALELFRP FIYAKLESRG YATTIKAAKK MVEREDAIVW DILAEVIREH 

       430        440        450        460        470        480 
PILLNRAPTL HRLGIQAFEP ILIEGKAIQL HPLVCAAFNA DFDGDQMAVH VPLTLEAQLE 

       490        500        510        520        530        540 
ARALMMSTNN VLSPANGDPI IVPSQDVVLG LYYMTREKVN GKGEGMLLQD PREAEKAYRT 

       550        560        570        580        590        600 
GEAELHSRVK VRITEYVKNE AGEFDAKTTL TDTTIGRAIL WMIAPKGMPY SLFNQTLGKK 

       610        620        630        640        650        660 
AISKLINEAY RRLGLKEAVM FADQIMYTGF AYAARSGSSV GIDDMEIPAK KYEIISAAEE 

       670        680        690        700        710        720 
EVAEIQEQFQ SGLVTAGERY NKVIDIWAAA NERVAKAMME NLSQEEVINR EGNPEKQASF 

       730        740        750        760        770        780 
NSIFMMADSG ARGSAAQIRQ LAGMRGLMAR PDGSIIETPI TANFREGLNV LQYFISTHGA 

       790        800        810        820        830        840 
RKGLADTALK TANSGYLTRR LVDVAQDLVI VEDDCGTHEG LVMTPLIEGG DEKVPLRELV 

       850        860        870        880        890        900 
LGRVAAEDIL KPGTEEVLIP RNTLLDEKLC DVLDANSVDS VKVRSVVTCD TDFGVCAKCY 

       910        920        930        940        950        960 
GRDLARGHLI NQGEAVGVIA AQSIGEPGTQ LTMRTFHIGG AASAAAKESS VQVKNTGTVH 

       970        980        990       1000       1010       1020 
LMNAKFVTND ESKLVLTSRN TELTITDAFG RTKEHYKVPY GAVLSKGDGQ EVTAGETIAN 

      1030       1040       1050       1060       1070       1080 
WDPHTMPVVS EVSGFVKFVD IIDGLTVTRQ TDELTGLSSI VVQDVGERAT AGKDLRPTIK 

      1090       1100       1110       1120       1130       1140 
LVDANGNDIF LPETDVLAQY FLPGKAIVSL DDGTAVKVGE PLARIPQESV GTKDITGGLP 

      1150       1160       1170       1180       1190       1200 
RVADLFEARK PKEPAILAEI SGIVSFGKET KGKRRLLITP AEGETYEEMI PKWRQLNVFE 

      1210       1220       1230       1240       1250       1260 
GEMVQRGDVI SDGAETPHDI LRLRGVRAVT EYIVNEVQDV YRLQGVKIND KHIEVIVRQM 

      1270       1280       1290       1300       1310       1320 
LRKAVITKAY DSEFLEGEQV EVARVKIVNR QREAEGKPPV EFERELLGIT KASLATESFI 

      1330       1340       1350       1360       1370       1380 
SAASFQETTR VLTEAAVAGK RDELRGLKEN VIVGRLIPAG TGFAYHQNRH KHRLVDDVVA 

      1390       1400       1410 
KLSEEDEAAI ADEFVITADD ATQNLATLLN SEIED

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L42023 Genomic DNA. Translation: AAC22172.1.
PIRG64073.
RefSeqNP_438672.1. NC_000907.1.

3D structure databases

ProteinModelPortalP43739.
SMRP43739. Positions 909-943, 945-1129.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID949579.
GenomeReviewsGene locus HI_0514 in contig L42023_GR.
KEGGhin:HI0514.
NMPDRfig|71421.1.peg.485.
PATRIC20189581. VBIHaeInf48452_0533.
TIGRHI_0514.

Phylogenomic databases

HOGENOMHBG621785.
OMADINDKHI.
PhylomeDBP43739.
ProtClustDBPRK00566.

Enzyme and pathway databases

BioCycHINF71421:HI_0514-MONOMER.

Family and domain databases

HAMAPMF_01322. RNApol_bact_RpoC.
[Tree]
InterProIPR012754. DNA-dir_RpoC_beta_prime.
IPR000722. RNA_pol_asu.
IPR006592. RNA_pol_N.
IPR007080. RNA_pol_Rpb1_1.
IPR007066. RNA_pol_Rpb1_3.
IPR007083. RNA_pol_Rpb1_4.
IPR007081. RNA_pol_Rpb1_5.
[Graphical view]
KOK03046.
PfamPF04997. RNA_pol_Rpb1_1. 1 hit.
PF00623. RNA_pol_Rpb1_2. 1 hit.
PF04983. RNA_pol_Rpb1_3. 1 hit.
PF05000. RNA_pol_Rpb1_4. 1 hit.
PF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
SMARTSM00663. RPOLA_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR02386. RpoC_TIGR. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRPOC_HAEIN
AccessionPrimary (citable) accession number: P43739
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: January 25, 2012
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

SIMILARITY comments

Index of protein domains and families

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