Skip Header

Contribute Send feedback
Read comments (?) or add your own

P43736 (DNAK_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chaperone protein DnaK
Alternative name(s):
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene names
Name:dnaK
Ordered Locus Names:HI_1237
OrganismHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]
Taxonomic identifier71421 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus ›

Protein attributes

Sequence length635 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Acts as a chaperone By similarity.

Induction

By stress conditions e.g. heat shock By similarity.

Sequence similarities

Belongs to the heat shock protein 70 family.

Ontologies

Keywords
   Biological processStress response
   LigandATP-binding
Nucleotide-binding
   Molecular functionChaperone
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: InterPro

response to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 635634Chaperone protein DnaK HAMAP-Rule MF_00332
PRO_0000078468

Amino acid modifications

Modified residue1981Phosphothreonine; by autocatalysis By similarity

Sequences

Sequence LengthMass (Da)Tools
P43736 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: 58167BFA0BA661C9

FASTA63568,281
        10         20         30         40         50         60 
MGKIIGIDLG TTNSCVAVMD GDKARVIENA EGARTTPSII AYTDNETLVG QPAKRQAITN 

        70         80         90        100        110        120 
PKNTLFAIKR LIGRRFESEE VQRDIKIMPF EITRADNGDA WVNVKGDKLA PPQISAEVLK 

       130        140        150        160        170        180 
KMKKTAEDFL GESVTEAVIT VPAYFNDAQR QATIDAGKIA GLDVKRIINE PTAAALAFGL 

       190        200        210        220        230        240 
GSSKENQVIA VYDLGGGTFD ISIIEIDNFD GEQTFEVLAT GGNTHLGGED FDNRVIDYII 

       250        260        270        280        290        300 
DEFKKEQNID LRNDAMALQR VKEAAEKAKI ELSSAQSTEV NLPYITADAT GPKHLALNIT 

       310        320        330        340        350        360 
RAKLEALVED LVASSIESLK AVLKDADKGV SEIHDIILVG GQTRMPLVQQ KVAEFFGKEA 

       370        380        390        400        410        420 
RKDVNPDEAV AIGAAVQGGV LKGDVKDVLL LDVTPLSLGI ETMGGVMTTL IEKNTTIPTK 

       430        440        450        460        470        480 
KSQVFSTAED NQSAVTIHVL QGERKRAADN KSLGQFNLEG INPAPRGMPQ IEVTFDIDAN 

       490        500        510        520        530        540 
GVINVSAKDK NTGKEQQIRI QASSGLSDEE IQQMVRDAEA NADADRKFEE VVQARNQADG 

       550        560        570        580        590        600 
IAHATRKQIA EAGDALSVAD KEKIEAAVAE LETAAKGEDK AEIEAKIEAV IKASEPLMQA 

       610        620        630 
VQAKAQQAGG EQPQQSSAKD DGVVDAEFEE VKDNK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L42023 Genomic DNA. Translation: AAC22889.1.
PIRB64112.
RefSeqNP_439393.1. NC_000907.1.

3D structure databases

ProteinModelPortalP43736.
SMRP43736. Positions 3-381, 388-604.
ModBaseSearch...

Protein-protein interaction databases

STRING71421.HI1237.

Proteomic databases

PRIDEP43736.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC22889; AAC22889; HI_1237.
GeneID950188.
KEGGhin:HI1237.
PATRIC20191153. VBIHaeInf48452_1289.

Phylogenomic databases

eggNOGCOG0443.
KOK04043.
OMAKDINLMP.
ProtClustDBPRK00290.

Family and domain databases

HAMAPMF_00332. DnaK.
InterProIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSPR00301. HEATSHOCK70.
TIGRFAMsTIGR02350. prok_dnaK. 1 hit.
PROSITEPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDNAK_HAEIN
AccessionPrimary (citable) accession number: P43736
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: January 23, 2007
Last modified: May 1, 2013
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Haemophilus influenzae

Haemophilus influenzae (strain Rd): entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents