P43723 (IHFA_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Integration host factor subunit alpha
Short name=IHF-alpha

Gene names

Name:	ihfA
Synonyms:	himA
Ordered Locus Names:	HI_1313

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	96 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control By similarity. HAMAP-Rule MF_00380
Subunit structure	Heterodimer of an alpha and a beta chain By similarity. HAMAP-Rule MF_00380
Sequence similarities	Belongs to the bacterial histone-like protein family.

Ontologies

Keywords
Biological process	DNA recombination Transcription Transcription regulation Translation regulation
Ligand	DNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA recombination Inferred from electronic annotation. Source: HAMAP regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: HAMAP regulation of translation Inferred from electronic annotation. Source: HAMAP transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 96	96	Integration host factor subunit alpha HAMAP-Rule MF_00380		PRO_0000105010

Sequences

	Sequence		Length	Mass (Da)
	P43723 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 891091C0CE6355EA	FASTA	96	10,907
	10 20 30 40 50 60 MATITKLDII EYLSDKYHLS KQDTKNVVEN FLEEIRLSLE SGQDVKLSGF GNFELRDKSS 70 80 90 RPGRNPKTGD VVPVSARRVV TFKPGQKLRA RVEKTK

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22959.1.
PIR	A64116.
RefSeq	NP_439464.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P43723.
SMR	P43723. Positions 4-93.
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI1313.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC22959; AAC22959; HI_1313.
GeneID	949629.
KEGG	hin:HI1313.
PATRIC	20191309. VBIHaeInf48452_1365.
Phylogenomic databases
eggNOG	COG0776.
KO	K04764.
OMA	FDLRDKK.
ProtClustDB	PRK00285.
Family and domain databases
Gene3D	4.10.520.10. 1 hit.
HAMAP	MF_00380. IHF-alpha.
InterPro	IPR023630. DNA-bd_HU/IHF. IPR000119. Hist_DNA-bd_bac. IPR020816. Histone-like_DNA-bd_CS. IPR010992. IHF-like_DNA-bd_dom. IPR005684. IHF_alpha. [Graphical view]
Pfam	PF00216. Bac_DNA_binding. 1 hit. [Graphical view]
PRINTS	PR01727. DNABINDINGHU.
SMART	SM00411. BHL. 1 hit. [Graphical view]
SUPFAM	SSF47729. IHF_like_DNA_bnd. 1 hit.
TIGRFAMs	TIGR00987. himA. 1 hit.
PROSITE	PS00045. HISTONE_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

IHFA_HAEIN

Accession

Primary (citable) accession number: P43723

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program