P43718 (ATPE_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ATP synthase epsilon chain

Alternative name(s):
ATP synthase F1 sector epsilon subunit
F-ATPase epsilon subunit

Gene names

Name:	atpC
Ordered Locus Names:	HI_0478

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	142 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. HAMAP MF_00530
Subunit structure	F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_00530.
Sequence similarities	Belongs to the ATPase epsilon chain family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(1) Cell inner membrane Cell membrane Membrane
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell proton-transporting ATP synthase complex, catalytic core F(1) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 142	142	ATP synthase epsilon chain HAMAP MF_00530		PRO_0000188142

Sequences

	Sequence		Length	Mass (Da)
	P43718 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: E5BBDE1DA34A9039	FASTA	142	15,591
	10 20 30 40 50 60 MATFNLTIVS AEQKIFEGEV KQIQVTGVEG ELGILPGHTP LLTAIKPGIV KFTLKDGNEE 70 80 90 100 110 120 VIYVSGGFLE VQPNIVTVLA DIAIRGSELD ADRIHEAKRK AEENIVSRGS DADHDLLVAK 130 140 LSKELAKLRA YELTEKLLKT RR

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed: 7542800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22136.1.
PIR	C64071.
RefSeq	NP_438638.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P43718.
SMR	P43718. Positions 2-136.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	950629.
GenomeReviews	Gene locus HI_0478 in contig L42023_GR.
KEGG	hin:HI0478.
PATRIC	20189509. VBIHaeInf48452_0497.
TIGR	HI_0478.
Phylogenomic databases
HOGENOM	HBG663981.
OMA	EMVSVRA.
PhylomeDB	P43718.
ProtClustDB	PRK00571.
Enzyme and pathway databases
BioCyc	HINF71421:HI_0478-MONOMER.
Family and domain databases
HAMAP	MF_00530. ATP_synth_epsil_bac. [Tree]
InterPro	IPR001469. ATPase_F1-cplx_dsu/esu. IPR020547. ATPase_F1-cplx_dsu/esu_C. IPR020546. ATPase_F1-cplx_dsu/esu_N. [Graphical view]
Gene3D	G3DSA:1.20.5.440. ATPase_F1_d/e. 1 hit. G3DSA:2.60.15.10. ATPase_F1_d/e. 1 hit.
KO	K02114.
PANTHER	PTHR13822. ATPase_F1_d/e. 1 hit.
Pfam	PF02823. ATP-synt_DE_N. 1 hit. [Graphical view]
ProDom	PD000944. ATPase_F1-cplx_dsu/esu. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF46604. ATPsynt_DE. 1 hit. SSF51344. ATPsynt_DE. 1 hit.
TIGRFAMs	TIGR01216. ATP_synt_epsi. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ATPE_HAEIN

Accession

Primary (citable) accession number: P43718

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	January 25, 2012
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program