SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P43712

- FABD_HAEIN

UniProt

P43712 - FABD_HAEIN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Malonyl CoA-acyl carrier protein transacylase
Gene
fabD, HI_0156
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein].

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei93 – 931 By similarity
Active sitei202 – 2021 By similarity

GO - Molecular functioni

  1. [acyl-carrier-protein] S-malonyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
Malonyl CoA-acyl carrier protein transacylase (EC:2.3.1.39)
Short name:
MCT
Gene namesi
Name:fabD
Ordered Locus Names:HI_0156
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 312312Malonyl CoA-acyl carrier protein transacylase
PRO_0000194216Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0156.

Structurei

3D structure databases

ProteinModelPortaliP43712.
SMRiP43712. Positions 3-310.

Family & Domainsi

Sequence similaritiesi

Belongs to the FabD family.

Phylogenomic databases

eggNOGiCOG0331.
KOiK00645.
OMAiIWRVWQE.
OrthoDBiEOG6W19KW.
PhylomeDBiP43712.

Family and domain databases

Gene3Di3.40.366.10. 2 hits.
InterProiIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view]
PfamiPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000446. Mct. 1 hit.
SUPFAMiSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsiTIGR00128. fabD. 1 hit.

Sequencei

Sequence statusi: Complete.

P43712-1 [UniParc]FASTAAdd to Basket

« Hide

MKKFAMVFPG QGSQTVGMLA DLATEYPIVI ETFKQASDAL GYDLWYLVQQ    50
GPAEELNKTW QTQPALLAAS VAIYRVWKEK FPQLKPEVMA GHSLGEYSAL 100
VCAGVLDFQD AIKLVELRGK LMQQAVPEGT GAMYAIIGLD NEAIINACKQ 150
AEEGEVVSAV NFNSPGQVVI AGAKAAVERA AALCKEAGAK RALPLAVSVP 200
SHCALMKPAA EQLAVTLENI QINTPTISVL NNVDVKAETE GTEIRTALVR 250
QLYSPVRWTE TVEKMAQDGV LVLAEVGPGK VLNGLTKRIV GDLQAISVND 300
VASFNAVEEF LV 312
Length:312
Mass (Da):33,425
Last modified:November 1, 1995 - v1
Checksum:i6261622B834AE878
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC21825.1.
PIRiE64051.
RefSeqiNP_438326.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC21825; AAC21825; HI_0156.
GeneIDi951062.
KEGGihin:HI0156.
PATRICi20188807. VBIHaeInf48452_0160.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L42023 Genomic DNA. Translation: AAC21825.1 .
PIRi E64051.
RefSeqi NP_438326.1. NC_000907.1.

3D structure databases

ProteinModelPortali P43712.
SMRi P43712. Positions 3-310.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 71421.HI0156.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC21825 ; AAC21825 ; HI_0156 .
GeneIDi 951062.
KEGGi hin:HI0156.
PATRICi 20188807. VBIHaeInf48452_0160.

Phylogenomic databases

eggNOGi COG0331.
KOi K00645.
OMAi IWRVWQE.
OrthoDBi EOG6W19KW.
PhylomeDBi P43712.

Enzyme and pathway databases

UniPathwayi UPA00094 .

Family and domain databases

Gene3Di 3.40.366.10. 2 hits.
InterProi IPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view ]
Pfami PF00698. Acyl_transf_1. 1 hit.
[Graphical view ]
PIRSFi PIRSF000446. Mct. 1 hit.
SUPFAMi SSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsi TIGR00128. fabD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiFABD_HAEIN
AccessioniPrimary (citable) accession number: P43712
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: September 3, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi