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Protein

Oxytetracycline polyketide synthase acyl carrier protein

Gene
N/A
Organism
Streptomyces rimosus
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Acyl carrier protein.

Pathwayi: oxytetracycline biosynthesis

This protein is involved in the pathway oxytetracycline biosynthesis, which is part of Antibiotic biosynthesis.
View all proteins of this organism that are known to be involved in the pathway oxytetracycline biosynthesis and in Antibiotic biosynthesis.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Antibiotic biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00926.

Names & Taxonomyi

Protein namesi
Recommended name:
Oxytetracycline polyketide synthase acyl carrier protein
Short name:
ACP
OrganismiStreptomyces rimosus
Taxonomic identifieri1927 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001802531 – 95Oxytetracycline polyketide synthase acyl carrier proteinAdd BLAST95

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei41O-(pantetheine 4'-phosphoryl)serineCurated1

Post-translational modificationi

4'-phosphopantetheine is transferred from CoA to a specific serine of the apo-ACP-like protein.Curated

Keywords - PTMi

Phosphopantetheine, Phosphoprotein

Structurei

Secondary structure

195
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 17Combined sources12
Beta strandi30 – 32Combined sources3
Helixi34 – 37Combined sources4
Helixi42 – 54Combined sources13
Helixi63 – 66Combined sources4
Helixi70 – 83Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1NQ4NMR-A1-95[»]
ProteinModelPortaliP43677.
SMRiP43677.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP43677.

Family & Domainsi

Sequence similaritiesi

Contains 1 acyl carrier domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di1.10.1200.10. 1 hit.
InterProiIPR009081. PP-bd_ACP.
IPR006162. Ppantetheine_attach_site.
[Graphical view]
PfamiPF00550. PP-binding. 1 hit.
[Graphical view]
SUPFAMiSSF47336. SSF47336. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P43677-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLLTLSDLL TLLRECAGEE ESIDLGGDVE DVAFDALGYD SLALLNTVGR
60 70 80 90
IERDYGVQLG DDAVEKATTP RALIEMTNAS LTGASPSAGG AARDK
Length:95
Mass (Da):9,916
Last modified:November 1, 1995 - v1
Checksum:iD0C92084807BB244
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z25538 Genomic DNA. Translation: CAA80986.1.
U01666 Genomic DNA. Translation: AAA03334.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z25538 Genomic DNA. Translation: CAA80986.1.
U01666 Genomic DNA. Translation: AAA03334.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1NQ4NMR-A1-95[»]
ProteinModelPortaliP43677.
SMRiP43677.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00926.

Miscellaneous databases

EvolutionaryTraceiP43677.

Family and domain databases

Gene3Di1.10.1200.10. 1 hit.
InterProiIPR009081. PP-bd_ACP.
IPR006162. Ppantetheine_attach_site.
[Graphical view]
PfamiPF00550. PP-binding. 1 hit.
[Graphical view]
SUPFAMiSSF47336. SSF47336. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiACPX_STRRM
AccessioniPrimary (citable) accession number: P43677
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.