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Protein

Probable low-affinity inorganic phosphate transporter 2

Gene

pitB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Low-affinity inorganic phosphate transport.By similarity

GO - Molecular functioni

  • inorganic phosphate transmembrane transporter activity Source: EcoCyc

GO - Biological processi

  • phosphate ion transmembrane transport Source: EcoCyc

Keywordsi

Biological processPhosphate transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:PITB-MONOMER
MetaCyc:PITB-MONOMER

Protein family/group databases

TCDBi2.A.20.1.2 the inorganic phosphate transporter (pit) family

Names & Taxonomyi

Protein namesi
Recommended name:
Probable low-affinity inorganic phosphate transporter 2
Gene namesi
Name:pitB
Ordered Locus Names:b2987, JW2955
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12883 pitB

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei5 – 25HelicalSequence analysisAdd BLAST21
Transmembranei52 – 72HelicalSequence analysisAdd BLAST21
Transmembranei94 – 114HelicalSequence analysisAdd BLAST21
Transmembranei124 – 144HelicalSequence analysisAdd BLAST21
Transmembranei155 – 175HelicalSequence analysisAdd BLAST21
Transmembranei207 – 227HelicalSequence analysisAdd BLAST21
Transmembranei233 – 253HelicalSequence analysisAdd BLAST21
Transmembranei382 – 402HelicalSequence analysisAdd BLAST21
Transmembranei430 – 450HelicalSequence analysisAdd BLAST21
Transmembranei473 – 493HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: EcoCyc
  • integral component of plasma membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000807851 – 499Probable low-affinity inorganic phosphate transporter 2Add BLAST499

Proteomic databases

PaxDbiP43676
PRIDEiP43676

Interactioni

Protein-protein interaction databases

BioGridi4261181, 20 interactors
STRINGi316385.ECDH10B_3164

Structurei

3D structure databases

ProteinModelPortaliP43676
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CJ3 Bacteria
COG0306 LUCA
HOGENOMiHOG000231893
InParanoidiP43676
KOiK16322
OMAiAGGWRIM
PhylomeDBiP43676

Family and domain databases

InterProiView protein in InterPro
IPR001204 Phos_transporter
PANTHERiPTHR11101 PTHR11101, 1 hit
PfamiView protein in Pfam
PF01384 PHO4, 1 hit

Sequencei

Sequence statusi: Complete.

P43676-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNLFVGLDI YTGLLLLLAL AFVLFYEAIN GFHDTANAVA AVIYTRAMQP
60 70 80 90 100
QLAVVMAAFF NFFGVLLGGL SVAYAIVHML PTDLLLNMGS THGLAMVFSM
110 120 130 140 150
LLAAIIWNLG TWFFGLPASS SHTLIGAIIG IGLTNALLTG SSVMDALNLR
160 170 180 190 200
EVTKIFSSLI VSPIVGLVIA GGLIFLLRRY WSGTKKRDRI HRIPEDRKKK
210 220 230 240 250
KGKRKPPFWT RIALIVSAAG VAFSHGANDG QKGIGLVMLV LVGIAPAGFV
260 270 280 290 300
VNMNASGYEI TRTRDAVTNF EHYLQQHPEL PQKLIAMEPP LPAASTDGTQ
310 320 330 340 350
VTEFHCHPAN TFDAIARVKT MLPGNMESYE PLSVSQRSQL RRIMLCISDT
360 370 380 390 400
SAKLAKLPGV SKEDQNLLKK LRSDMLSTIE YAPVWIIMAV ALALGIGTMI
410 420 430 440 450
GWRRVAMTIG EKIGKRGMTY AQGMAAQMTA AVSIGLASYI GMPVSTTHVL
460 470 480 490
SSAVAGTMVV DGGGLQRKTV TSILMAWVFT LPAAIFLSGG LYWIALQLI
Length:499
Mass (Da):53,809
Last modified:November 1, 1995 - v1
Checksum:i1D3677057FAB295B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti182S → C in AAC43340 (PubMed:7775463).Curated1
Sequence conflicti213A → G in AAC43340 (PubMed:7775463).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA Translation: AAA69154.1
U00096 Genomic DNA Translation: AAC76023.1
AP009048 Genomic DNA Translation: BAE77048.1
U23148 Genomic DNA Translation: AAC43340.1
PIRiA65085
RefSeqiNP_417461.1, NC_000913.3
WP_000933250.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76023; AAC76023; b2987
BAE77048; BAE77048; BAE77048
GeneIDi947475
KEGGiecj:JW2955
eco:b2987
PATRICifig|1411691.4.peg.3743

Similar proteinsi

Entry informationi

Entry nameiPITB_ECOLI
AccessioniPrimary (citable) accession number: P43676
Secondary accession number(s): Q2M9K8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
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