Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Casein kinase II subunit beta

Gene

CKB1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a complex role in regulating the basal catalytic activity of the alpha subunit.By similarity

Miscellaneous

Present with 8120 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • protein kinase regulator activity Source: SGD
  • protein serine/threonine kinase inhibitor activity Source: SGD

GO - Biological processi

  • cellular response to DNA damage stimulus Source: SGD
  • peptidyl-serine phosphorylation Source: SGD
  • peptidyl-threonine phosphorylation Source: SGD
  • protein phosphorylation Source: SGD
  • regulation of transcription by RNA polymerase I Source: SGD
  • regulation of transcription by RNA polymerase III Source: SGD
  • rRNA methylation Source: Reactome

Enzyme and pathway databases

BioCyciYEAST:G3O-30539-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Casein kinase II subunit beta
Short name:
CK II beta
Gene namesi
Name:CKB1
Ordered Locus Names:YGL019W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGL019W
SGDiS000002987 CKB1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00000682572 – 278Casein kinase II subunit betaAdd BLAST277

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1
Modified residuei2PhosphoserineCombined sources1

Post-translational modificationi

Phosphorylated by alpha subunit.By similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiP43639
PaxDbiP43639
PRIDEiP43639

PTM databases

iPTMnetiP43639

Interactioni

Subunit structurei

Tetramer composed of an alpha subunit, an alpha' subunit, one beta subunit and one beta' subunit. Interacts with FACT subunits POB3 and SPT16.1 Publication

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi33227, 503 interactors
DIPiDIP-282N
IntActiP43639, 79 interactors
MINTiP43639
STRINGi4932.YGL019W

Structurei

3D structure databases

ProteinModelPortaliP43639
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000039270
InParanoidiP43639
KOiK03115
OMAiWIHWFCK
OrthoDBiEOG092C4DSU

Family and domain databases

Gene3Di1.10.1820.10, 1 hit
InterProiView protein in InterPro
IPR016149 Casein_kin_II_reg-sub_N
IPR035991 Casein_kinase_II_beta_like
IPR000704 Casein_kinase_II_reg-sub
PANTHERiPTHR11740 PTHR11740, 1 hit
PfamiView protein in Pfam
PF01214 CK_II_beta, 1 hit
PRINTSiPR00472 CASNKINASEII
SMARTiView protein in SMART
SM01085 CK_II_beta, 1 hit
SUPFAMiSSF57798 SSF57798, 2 hits
PROSITEiView protein in PROSITE
PS01101 CK2_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P43639-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQEFVEDYS RTGSSDDEDS GAYDEWIPSF CSRFGHEYFC QVPTEFIEDD
60 70 80 90 100
FNMTSLSQEV PHYRKALDLI LDLEAMSDEE EDEDDVVEED EVDQEMQSND
110 120 130 140 150
GHDEGKRRNK SPVVNKSIIE HAAEQLYGLI HARFILTKPG LQAMAEKFDH
160 170 180 190 200
KEFGTCPRYY CNGMQLLPCG LSDTVGKHTV RLYCPSCQDL YLPQSSRFLC
210 220 230 240 250
LEGAFWGTSF PGVFLKHFKE LEEYVERKSK ESYELKVFGF RINDEAVSGP
260 270
RMKWLRQYPS TEEDWEEFAK CEFETPAV
Length:278
Mass (Da):32,265
Last modified:November 1, 1995 - v1
Checksum:i9ACA8D285E6990AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U21283 Genomic DNA Translation: AAA86829.1
Z72541 Genomic DNA Translation: CAA96719.1
BK006941 Genomic DNA Translation: DAA08079.1
PIRiA56421
RefSeqiNP_011496.3, NM_001180884.3

Genome annotation databases

EnsemblFungiiYGL019W; YGL019W; YGL019W
GeneIDi852865
KEGGisce:YGL019W

Similar proteinsi

Entry informationi

Entry nameiCSK2B_YEAST
AccessioniPrimary (citable) accession number: P43639
Secondary accession number(s): D6VUB8, Q9URG5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 23, 2018
This is version 166 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health