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P43618 (CNN1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Kinetochore-associated protein CNN1
Alternative name(s):
Co-purified with NNF1 protein 1
Gene names
Name:CNN1
Ordered Locus Names:YFR046C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length361 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Component of the kinetochore. Interacts with NNF1. Ref.5

Subcellular location

Nucleus. Chromosomecentromerekinetochore Ref.6.

Miscellaneous

Present with 1300 molecules/cell in log phase SD medium.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

NUF2P338952EBI-23036,EBI-12377

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 361361Kinetochore-associated protein CNN1
PRO_0000202697

Experimental info

Sequence conflict81A → T in AAT92741. Ref.2

Secondary structure

... 361
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P43618 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 48CEEC087A056D42

FASTA36141,313
        10         20         30         40         50         60 
MSTPRKAAGN NENTEVSEIR TPFRERALEE QRLKDEVLIR NTPGYRKLLS ASTKSHDILN 

        70         80         90        100        110        120 
KDPNEVRSFL QDLSQVLARK SQGNDTTTNK TQARNLIDEL AYEESQPEEN ELLRSRSEKL 

       130        140        150        160        170        180 
TDNNIGNETQ PDYTSLSQTV FAKLQERDKG LKSRKIDPII IQDVPTTGHE DELTVHSPDK 

       190        200        210        220        230        240 
ANSISMEVLR TSPSIGMDQV DEPPVRDPVP ISITQQEEPL SEDLPSDDKE ETEEAENEDY 

       250        260        270        280        290        300 
SFENTSDENL DDIGNDPIRL NVPAVRRSSI KPLQIMDLKH LTRQFLNENR IILPKQTWST 

       310        320        330        340        350        360 
IQEESLNIMD FLKQKIGTLQ KQELVDSFID MGIINNVDDM FELAHELLPL ELQSRIESYL 


F 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of a 36.2 kb DNA sequence including the right telomere of chromosome VI from Saccharomyces cerevisiae."
Eki T., Naitou M., Hagiwara H., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Shibata T., Hanaoka F., Murakami Y.
Yeast 12:149-167(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae."
Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T.
Nat. Genet. 10:261-268(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes."
De Wulf P., McAinsh A.D., Sorger P.K.
Genes Dev. 17:2902-2921(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH NNF1, IDENTIFICATION BY MASS SPECTROMETRY.
[6]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[7]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[8]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D50617 Genomic DNA. Translation: BAA09285.1.
AY692722 Genomic DNA. Translation: AAT92741.1.
BK006940 Genomic DNA. Translation: DAA12489.1.
PIRS56301.
RefSeqNP_116704.1. NM_001180011.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4GEQX-ray2.01E/F60-84[»]
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid31204. 39 interactions.
DIPDIP-5186N.
IntActP43618. 4 interactions.
MINTMINT-557134.
STRING4932.YFR046C.

Proteomic databases

PaxDbP43618.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYFR046C; YFR046C; YFR046C.
GeneID850607.
KEGGsce:YFR046C.

Organism-specific databases

CYGDYFR046c.
SGDS000001942. CNN1.

Phylogenomic databases

eggNOGNOG132497.
OrthoDBEOG7FBRW8.

Enzyme and pathway databases

BioCycYEAST:G3O-30493-MONOMER.

Gene expression databases

GenevestigatorP43618.

Family and domain databases

ProtoNetSearch...

Other

NextBio966487.

Entry information

Entry nameCNN1_YEAST
AccessionPrimary (citable) accession number: P43618
Secondary accession number(s): D6VTS9, Q6B2K8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: June 11, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VI

Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

PDB cross-references

Index of Protein Data Bank (PDB) cross-references