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P43617

- YFL5_YEAST

UniProt

P43617 - YFL5_YEAST

Protein

Uncharacterized mitochondrial carrier YFR045W

Gene

YFR045W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 121 (01 Oct 2014)
      Sequence version 3 (16 Jun 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. transporter activity Source: SGD

    GO - Biological processi

    1. transmembrane transport Source: InterPro
    2. transport Source: SGD

    Keywords - Biological processi

    Transport

    Enzyme and pathway databases

    BioCyciYEAST:G3O-30492-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized mitochondrial carrier YFR045W
    Gene namesi
    Ordered Locus Names:YFR045W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VI

    Organism-specific databases

    CYGDiYFR045w.
    SGDiS000001941. YFR045W.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial inner membrane Source: SGD

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 309309Uncharacterized mitochondrial carrier YFR045WPRO_0000090695Add
    BLAST

    Proteomic databases

    MaxQBiP43617.
    PaxDbiP43617.
    PeptideAtlasiP43617.

    Expressioni

    Gene expression databases

    GenevestigatoriP43617.

    Interactioni

    Protein-protein interaction databases

    BioGridi31203. 18 interactions.
    DIPiDIP-5570N.
    MINTiMINT-472522.
    STRINGi4932.YFR045W.

    Structurei

    3D structure databases

    ProteinModelPortaliP43617.
    SMRiP43617. Positions 142-308.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei12 – 3221Helical; Name=1Sequence AnalysisAdd
    BLAST
    Transmembranei47 – 6721Helical; Name=2Sequence AnalysisAdd
    BLAST
    Transmembranei100 – 12021Helical; Name=3Sequence AnalysisAdd
    BLAST
    Transmembranei184 – 20421Helical; Name=4Sequence AnalysisAdd
    BLAST
    Transmembranei222 – 24221Helical; Name=5Sequence AnalysisAdd
    BLAST
    Transmembranei285 – 30521Helical; Name=6Sequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati6 – 8378Solcar 1Add
    BLAST
    Repeati97 – 211115Solcar 2Add
    BLAST
    Repeati216 – 30287Solcar 3Add
    BLAST

    Sequence similaritiesi

    Contains 3 Solcar repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG269632.
    HOGENOMiHOG000168307.
    OMAiFITFTRQ.
    OrthoDBiEOG71K6CH.

    Family and domain databases

    Gene3Di1.50.40.10. 1 hit.
    InterProiIPR002067. Mit_carrier.
    IPR018108. Mitochondrial_sb/sol_carrier.
    IPR023395. Mt_carrier_dom.
    [Graphical view]
    PfamiPF00153. Mito_carr. 3 hits.
    [Graphical view]
    PRINTSiPR00926. MITOCARRIER.
    SUPFAMiSSF103506. SSF103506. 1 hit.
    PROSITEiPS50920. SOLCAR. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P43617-1 [UniParc]FASTAAdd to Basket

    « Hide

    MANQNSDLYK QITAGSVAAV FQTTMTYPFE YLKTGLQLQP KGTAFEIILP    50
    QIKSYFVGCS ALNVAAFGKT ILRFVTFDKL CHSLNNNIDN NDNFQRLTGY 100
    NLLIAGTLTG IVESLFIIPF ENIKTTLIQS AMIDHKKLEK NQPVVNAKAT 150
    FHKVATKSTP VARIEKLLPA VKHMYQTRGP AAFVQGTTAT IFRQIANTSI 200
    QFTAYTAFKR LLQARNDKAS SVITGLATSF TLVAMTQPID VVKTRMMSQN 250
    AKTEYKNTLN CMYRIFVQEG MATFWKGSIF RFMKVGISGG LTFTVYEQVS 300
    LLLGFSSRS 309
    Length:309
    Mass (Da):34,391
    Last modified:June 16, 2009 - v3
    Checksum:i3E91A548BD4634EC
    GO

    Sequence cautioni

    The sequence BAA09284.1 differs from that shown. Reason: Frameshift at position 41.
    The sequence AAL26494.1 differs from that shown. Reason: Erroneous initiation.
    The sequence BAA09284.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D50617 Genomic DNA. Translation: BAA09284.1. Sequence problems.
    AF419345 Genomic DNA. Translation: AAL26494.1. Different initiation.
    AY558474 Genomic DNA. Translation: AAS56800.1.
    BK006940 Genomic DNA. Translation: DAA12488.1.
    PIRiS56300.
    RefSeqiNP_116703.5. NM_001180010.3.

    Genome annotation databases

    EnsemblFungiiYFR045W; YFR045W; YFR045W.
    GeneIDi850606.
    KEGGisce:YFR045W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D50617 Genomic DNA. Translation: BAA09284.1 . Sequence problems.
    AF419345 Genomic DNA. Translation: AAL26494.1 . Different initiation.
    AY558474 Genomic DNA. Translation: AAS56800.1 .
    BK006940 Genomic DNA. Translation: DAA12488.1 .
    PIRi S56300.
    RefSeqi NP_116703.5. NM_001180010.3.

    3D structure databases

    ProteinModelPortali P43617.
    SMRi P43617. Positions 142-308.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 31203. 18 interactions.
    DIPi DIP-5570N.
    MINTi MINT-472522.
    STRINGi 4932.YFR045W.

    Proteomic databases

    MaxQBi P43617.
    PaxDbi P43617.
    PeptideAtlasi P43617.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YFR045W ; YFR045W ; YFR045W .
    GeneIDi 850606.
    KEGGi sce:YFR045W.

    Organism-specific databases

    CYGDi YFR045w.
    SGDi S000001941. YFR045W.

    Phylogenomic databases

    eggNOGi NOG269632.
    HOGENOMi HOG000168307.
    OMAi FITFTRQ.
    OrthoDBi EOG71K6CH.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-30492-MONOMER.

    Miscellaneous databases

    NextBioi 966484.

    Gene expression databases

    Genevestigatori P43617.

    Family and domain databases

    Gene3Di 1.50.40.10. 1 hit.
    InterProi IPR002067. Mit_carrier.
    IPR018108. Mitochondrial_sb/sol_carrier.
    IPR023395. Mt_carrier_dom.
    [Graphical view ]
    Pfami PF00153. Mito_carr. 3 hits.
    [Graphical view ]
    PRINTSi PR00926. MITOCARRIER.
    SUPFAMi SSF103506. SSF103506. 1 hit.
    PROSITEi PS50920. SOLCAR. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of a 36.2 kb DNA sequence including the right telomere of chromosome VI from Saccharomyces cerevisiae."
      Eki T., Naitou M., Hagiwara H., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Shibata T., Hanaoka F., Murakami Y.
      Yeast 12:149-167(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204511 / S288c / AB972.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. "The yeast mitochondrial transport proteins: new sequences and consensus residues, lack of direct relation between consensus residues and transmembrane helices, expression patterns of the transport protein genes, and protein-protein interactions with other proteins."
      Belenkiy R., Haefele A., Eisen M.B., Wohlrab H.
      Biochim. Biophys. Acta 1467:207-218(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 5-309, IDENTIFICATION OF FRAMESHIFT.
    5. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 132-309.
      Strain: ATCC 204508 / S288c.
    6. "A large-scale full-length cDNA analysis to explore the budding yeast transcriptome."
      Miura F., Kawaguchi N., Sese J., Toyoda A., Hattori M., Morishita S., Ito T.
      Proc. Natl. Acad. Sci. U.S.A. 103:17846-17851(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION OF INTRON.

    Entry informationi

    Entry nameiYFL5_YEAST
    AccessioniPrimary (citable) accession number: P43617
    Secondary accession number(s): D6VTS8, Q96US0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: June 16, 2009
    Last modified: October 1, 2014
    This is version 121 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome VI
      Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

    External Data

    Dasty 3