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P43617 (YFL5_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 120. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized mitochondrial carrier YFR045W
Gene names
Ordered Locus Names:YFR045W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length309 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]

Contains 3 Solcar repeats.

Sequence caution

The sequence AAL26494.1 differs from that shown. Reason: Erroneous initiation.

The sequence BAA09284.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence BAA09284.1 differs from that shown. Reason: Frameshift at position 41.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 309309Uncharacterized mitochondrial carrier YFR045W
PRO_0000090695

Regions

Transmembrane12 – 3221Helical; Name=1; Potential
Transmembrane47 – 6721Helical; Name=2; Potential
Transmembrane100 – 12021Helical; Name=3; Potential
Transmembrane184 – 20421Helical; Name=4; Potential
Transmembrane222 – 24221Helical; Name=5; Potential
Transmembrane285 – 30521Helical; Name=6; Potential
Repeat6 – 8378Solcar 1
Repeat97 – 211115Solcar 2
Repeat216 – 30287Solcar 3

Sequences

Sequence LengthMass (Da)Tools
P43617 [UniParc].

Last modified June 16, 2009. Version 3.
Checksum: 3E91A548BD4634EC

FASTA30934,391
        10         20         30         40         50         60 
MANQNSDLYK QITAGSVAAV FQTTMTYPFE YLKTGLQLQP KGTAFEIILP QIKSYFVGCS 

        70         80         90        100        110        120 
ALNVAAFGKT ILRFVTFDKL CHSLNNNIDN NDNFQRLTGY NLLIAGTLTG IVESLFIIPF 

       130        140        150        160        170        180 
ENIKTTLIQS AMIDHKKLEK NQPVVNAKAT FHKVATKSTP VARIEKLLPA VKHMYQTRGP 

       190        200        210        220        230        240 
AAFVQGTTAT IFRQIANTSI QFTAYTAFKR LLQARNDKAS SVITGLATSF TLVAMTQPID 

       250        260        270        280        290        300 
VVKTRMMSQN AKTEYKNTLN CMYRIFVQEG MATFWKGSIF RFMKVGISGG LTFTVYEQVS 


LLLGFSSRS 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of a 36.2 kb DNA sequence including the right telomere of chromosome VI from Saccharomyces cerevisiae."
Eki T., Naitou M., Hagiwara H., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Shibata T., Hanaoka F., Murakami Y.
Yeast 12:149-167(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae."
Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T.
Nat. Genet. 10:261-268(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"The yeast mitochondrial transport proteins: new sequences and consensus residues, lack of direct relation between consensus residues and transmembrane helices, expression patterns of the transport protein genes, and protein-protein interactions with other proteins."
Belenkiy R., Haefele A., Eisen M.B., Wohlrab H.
Biochim. Biophys. Acta 1467:207-218(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 5-309, IDENTIFICATION OF FRAMESHIFT.
[5]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 132-309.
Strain: ATCC 204508 / S288c.
[6]"A large-scale full-length cDNA analysis to explore the budding yeast transcriptome."
Miura F., Kawaguchi N., Sese J., Toyoda A., Hattori M., Morishita S., Ito T.
Proc. Natl. Acad. Sci. U.S.A. 103:17846-17851(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION OF INTRON.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D50617 Genomic DNA. Translation: BAA09284.1. Sequence problems.
AF419345 Genomic DNA. Translation: AAL26494.1. Different initiation.
AY558474 Genomic DNA. Translation: AAS56800.1.
BK006940 Genomic DNA. Translation: DAA12488.1.
PIRS56300.
RefSeqNP_116703.5. NM_001180010.3.

3D structure databases

ProteinModelPortalP43617.
SMRP43617. Positions 142-308.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid31203. 18 interactions.
DIPDIP-5570N.
MINTMINT-472522.
STRING4932.YFR045W.

Proteomic databases

MaxQBP43617.
PaxDbP43617.
PeptideAtlasP43617.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYFR045W; YFR045W; YFR045W.
GeneID850606.
KEGGsce:YFR045W.

Organism-specific databases

CYGDYFR045w.
SGDS000001941. YFR045W.

Phylogenomic databases

eggNOGNOG269632.
HOGENOMHOG000168307.
OMAFITFTRQ.
OrthoDBEOG71K6CH.

Enzyme and pathway databases

BioCycYEAST:G3O-30492-MONOMER.

Gene expression databases

GenevestigatorP43617.

Family and domain databases

Gene3D1.50.40.10. 1 hit.
InterProIPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSPR00926. MITOCARRIER.
SUPFAMSSF103506. SSF103506. 1 hit.
PROSITEPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio966484.

Entry information

Entry nameYFL5_YEAST
AccessionPrimary (citable) accession number: P43617
Secondary accession number(s): D6VTS8, Q96US0
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: June 16, 2009
Last modified: June 11, 2014
This is version 120 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VI

Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families