P43607 (RRT5_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Regulator of rDNA transcription protein 5

Gene names

Name:	RRT5
Ordered Locus Names:	YFR032C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	289 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	May be involved in the modulation of rDNA transcription. Ref.6
Induction	Specifically expressed during sporulation. Ref.4
Miscellaneous	Present with 51100 molecules/cell in log phase SD medium.
Sequence similarities	Belongs to the RRT5 family. Contains 1 RRM (RNA recognition motif) domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	RNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 289	289	Regulator of rDNA transcription protein 5		PRO_0000082029
Regions
	Domain	18 – 105	88	RRM

Sequences

	Sequence		Length	Mass (Da)
	P43607 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 24BC54340793F3A1	FASTA	289	31,865
	10 20 30 40 50 60 MTEQVNNDTT SDTTTTITTV YISNLPFTAS ERDLHAFLNN YGASSVLIPT QTVRRFSKRH 70 80 90 100 110 120 NSNPRKPLGI AFAQFANNTL ALKAIQDLNG TVFQNQKLFL KLHVPYEADS TPDTDVKKPK 130 140 150 160 170 180 EKNKVKKTPE TAADTVYCHD LPDDITDSEI RELFQLYSPQ EIWIYRSKVY RRKCIPFAPH 190 200 210 220 230 240 QITAALVTLQ SETPIGDICD SVAKTATLRG KSIIVKPAYV SKIQEIKQLV KDNLTNARDP 250 260 270 280 PPAALAEPAP APAPVEPAEQ VQEGQDNAET NDVPPPPASS SDRPTVAAT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae." Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T. Nat. Genet. 10:261-268(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Fifteen open reading frames in a 30.8 kb region of the right arm of chromosome VI from Saccharomyces cerevisiae." Eki T., Naitou M., Hagiwara H., Abe M., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Shibata T., Watanabe K., Ono A., Yamazaki M., Tashiro H., Hanaoka F., Murakami Y. Yeast 12:177-190(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[4]	"Expression profiles of transcripts from 126 open reading frames in the entire chromosome VI of Saccharomyces cerevisiae by systematic northern analyses." Naitou M., Hagiwara H., Hanaoka F., Eki T., Murakami Y. Yeast 13:1275-1290(1997) [PubMed] [Europe PMC] [Abstract] Cited for: INDUCTION.
[5]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]	"Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae." Hontz R.D., Niederer R.O., Johnson J.M., Smith J.S. Genetics 182:105-119(2009) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D50617 Genomic DNA. Translation: BAA09271.1. BK006940 Genomic DNA. Translation: DAA12473.1.
PIR	S56287.
RefSeq	NP_116689.1. NM_001179997.1.
3D structure databases
ProteinModelPortal	P43607.
SMR	P43607. Positions 132-219.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-1808N.
IntAct	P43607. 1 interaction.
MINT	MINT-393513.
STRING	4932.YFR032C.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YFR032C; YFR032C; YFR032C.
GeneID	850591.
KEGG	sce:YFR032C.
Organism-specific databases
CYGD	YFR032c.
SGD	S000001928. RRT5.
Phylogenomic databases
eggNOG	NOG282384.
OMA	RMQRTIS.
OrthoDB	EOG4S4SRP.
Gene expression databases
Genevestigator	P43607.
GermOnline	YFR032C. Saccharomyces cerevisiae.
Family and domain databases
Gene3D	3.30.70.330. 2 hits.
InterPro	IPR012677. Nucleotide-bd_a/b_plait. IPR000504. RRM_dom. [Graphical view]
SMART	SM00360. RRM. 1 hit. [Graphical view]
PROSITE	PS50102. RRM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	966440.

Entry information

Entry name

RRT5_YEAST

Accession

Primary (citable) accession number: P43607
Secondary accession number(s): D6VTR3

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 97 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program