ID   YFI8_YEAST              Reviewed;         363 AA.
AC   P43599; D6VTP9;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   08-NOV-2023, entry version 145.
DE   RecName: Full=Uncharacterized protein YFR018C;
GN   OrderedLocusNames=YFR018C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=7670463; DOI=10.1038/ng0795-261;
RA   Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S.,
RA   Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H.,
RA   Eki T.;
RT   "Analysis of the nucleotide sequence of chromosome VI from Saccharomyces
RT   cerevisiae.";
RL   Nat. Genet. 10:261-268(1995).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [4]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
CC   -!- MISCELLANEOUS: Present with 3970 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
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DR   EMBL; D50617; BAA09257.1; -; Genomic_DNA.
DR   EMBL; AY692564; AAT92583.1; -; Genomic_DNA.
DR   EMBL; BK006940; DAA12459.1; -; Genomic_DNA.
DR   PIR; S56273; S56273.
DR   RefSeq; NP_116673.1; NM_001179983.1.
DR   AlphaFoldDB; P43599; -.
DR   SMR; P43599; -.
DR   BioGRID; 31171; 50.
DR   DIP; DIP-5527N; -.
DR   STRING; 4932.YFR018C; -.
DR   PaxDb; 4932-YFR018C; -.
DR   PeptideAtlas; P43599; -.
DR   EnsemblFungi; YFR018C_mRNA; YFR018C; YFR018C.
DR   GeneID; 850573; -.
DR   KEGG; sce:YFR018C; -.
DR   AGR; SGD:S000001914; -.
DR   SGD; S000001914; YFR018C.
DR   VEuPathDB; FungiDB:YFR018C; -.
DR   eggNOG; KOG3946; Eukaryota.
DR   GeneTree; ENSGT00390000003107; -.
DR   HOGENOM; CLU_045003_1_1_1; -.
DR   InParanoid; P43599; -.
DR   OMA; CDRVRMP; -.
DR   OrthoDB; 3091175at2759; -.
DR   BioCyc; YEAST:G3O-30470-MONOMER; -.
DR   Reactome; R-SCE-6798695; Neutrophil degranulation.
DR   BioGRID-ORCS; 850573; 5 hits in 10 CRISPR screens.
DR   PRO; PR:P43599; -.
DR   Proteomes; UP000002311; Chromosome VI.
DR   RNAct; P43599; Protein.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:SGD.
DR   GO; GO:0016603; F:glutaminyl-peptide cyclotransferase activity; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR   CDD; cd03880; M28_QC_like; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR037457; M28_QC.
DR   InterPro; IPR007484; Peptidase_M28.
DR   InterPro; IPR040234; QC/QCL.
DR   PANTHER; PTHR12283; GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE; 1.
DR   PANTHER; PTHR12283:SF6; GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   1: Evidence at protein level;
KW   Acyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..363
FT                   /note="Uncharacterized protein YFR018C"
FT                   /id="PRO_0000202688"
SQ   SEQUENCE   363 AA;  41031 MW;  70B979735B4923BE CRC64;
     MGMKYVLPLR LIGLAYLLVL FQVHRVTGWE LSYEQYHAAH LNEAINPDSG WNKSTKNLLL
     PFNRTRVPGS EGSREIQRFI IEHFNNTLAG EWAVETQAFE ENGYRFNNLV MTLQNNASEY
     LVLAAHYDTK IAPTGMVGAI DSAASCAALL YTAQFLTHIA CHERTKEYND LESNTVVSNS
     TLGVKIVFFD GEEAIEEWGP EDSIYGARRL AAQWLADGTM TRIRLLFLLD LLGSGEEEPL
     VPSYYAETHQ EYQLLNRIED DLLFRRGDEI NGESALAAEV ARQRKHLDPT DYRFLGLGHS
     VIGDDHTPFL AAGVPVLHAI PLPFPSTWHT VDDDFRHLDA AETRHWALLV CEFVVQSLRS
     RNQ
//