P43598 (YFI7_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YFR017C

Gene names

Ordered Locus Names:

YFR017C

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	195 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Miscellaneous

Present with 639 molecules/cell in log phase SD medium. Ref.5

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	negative regulation of glycogen catabolic process Inferred from mutant phenotype. Source: SGD
Cellular component	cytoplasm Inferred from direct assay. Source: SGD
Molecular function	enzyme inhibitor activity Inferred from mutant phenotype. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 195	195	Uncharacterized protein YFR017C		PRO_0000202687
Amino acid modifications
	Modified residue	12	1	Phosphoserine Ref.8
	Modified residue	13	1	Phosphothreonine Ref.8
	Modified residue	14	1	Phosphoserine Ref.8
	Modified residue	64	1	Phosphoserine Ref.4 Ref.7 Ref.8
	Modified residue	65	1	Phosphothreonine Ref.7 Ref.8
	Modified residue	83	1	Phosphoserine Ref.7 Ref.8
	Modified residue	95	1	Phosphoserine Ref.8
	Modified residue	96	1	Phosphoserine Ref.4 Ref.7 Ref.8
	Modified residue	164	1	Phosphoserine Ref.8
	Modified residue	175	1	Phosphoserine Ref.6 Ref.8

Sequences

	Sequence		Length	Mass (Da)
	P43598 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 72A5C94EB59B4AB1	FASTA	195	21,783
	10 20 30 40 50 60 MTDPHLNTPQ VSTSPTFERS QDFLNIDEPP CAQETPSVST FNLPGPSAPA QSVDKPVPMI 70 80 90 100 110 120 RRRSTNYMDA LNSREQARER ESSIGEHAPG AERRSSGPMD FQNTIHNMQY RTTNDSDLSH 130 140 150 160 170 180 AGVDMGDSIS HTPICSRAGN RPIFKNSYLD NNSNGNSARV PHGSPPQLGT RRKSSFKYED 190 FKKDIYNQLH MFGEK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae." Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T. Nat. Genet. 10:261-268(1995) [PubMed: 7670463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[4]	"Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae." Ficarro S.B., McCleland M.L., Stukenberg P.T., Burke D.J., Ross M.M., Shabanowitz J., Hunt D.F., White F.M. Nat. Biotechnol. 20:301-305(2002) [PubMed: 11875433] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-64 AND SER-96, MASS SPECTROMETRY. Strain: 2124.
[5]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]	"Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry." Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F. Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed: 17287358] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-175, MASS SPECTROMETRY.
[7]	"Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases." Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H. Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed: 17563356] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-64; THR-65; SER-83 AND SER-96, MASS SPECTROMETRY.
[8]	"A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-12; THR-13; SER-14; SER-64; THR-65; SER-83; SER-95; SER-96; SER-164 AND SER-175, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D50617 Genomic DNA. Translation: BAA09256.1. AY558470 Genomic DNA. Translation: AAS56796.1. BK006940 Genomic DNA. Translation: DAA12458.1.
PIR	S43032.
RefSeq	NP_116672.1. NM_001179982.1.
3D structure databases
ProteinModelPortal	P43598.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-3799N.
IntAct	P43598. 3 interactions.
MINT	MINT-532832.
STRING	P43598.
Proteomic databases
PeptideAtlas	P43598.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YFR017C; YFR017C; YFR017C.
GeneID	850572.
KEGG	sce:YFR017C.
NMPDR	fig|4932.3.peg.2306.
Organism-specific databases
CYGD	YFR017c.
SGD	S000001913. YFR017C.
Phylogenomic databases
OrthoDB	EOG4GTPPW.
Gene expression databases
ArrayExpress	P43598.
Genevestigator	P43598.
GermOnline	YFR017C. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	966389.

Entry information

Entry name

YFI7_YEAST

Accession

Primary (citable) accession number: P43598
Secondary accession number(s): D6VTP8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	December 14, 2011
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program