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Protein

Transcriptional regulatory protein GAT1

Gene

GAT1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Positive regulator of multiple nitrogen catabolic genes.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri310 – 334GATA-typePROSITE-ProRule annotationAdd BLAST25

GO - Molecular functioni

GO - Biological processi

  • cell differentiation Source: GO_Central
  • nitrogen catabolite activation of transcription Source: SGD
  • nitrogen catabolite activation of transcription from RNA polymerase II promoter Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-30439-MONOMER.
ReactomeiR-SCE-5689880. Ub-specific processing proteases.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulatory protein GAT1
Gene namesi
Name:GAT1
Ordered Locus Names:YFL021W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VI

Organism-specific databases

EuPathDBiFungiDB:YFL021W.
SGDiS000001873. GAT1.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: SGD
  • nucleus Source: SGD
  • transcription factor complex Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000834841 – 510Transcriptional regulatory protein GAT1Add BLAST510

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei167PhosphoserineCombined sources1
Modified residuei262PhosphoserineCombined sources1
Modified residuei270PhosphoserineCombined sources1
Modified residuei369PhosphothreonineCombined sources1
Modified residuei399PhosphoserineCombined sources1
Modified residuei418PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP43574.
PRIDEiP43574.

PTM databases

iPTMnetiP43574.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi31125. 35 interactors.
DIPiDIP-4276N.
IntActiP43574. 7 interactors.
MINTiMINT-525395.

Structurei

3D structure databases

ProteinModelPortaliP43574.
SMRiP43574.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi151 – 158Poly-Asp8

Sequence similaritiesi

Contains 1 GATA-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri310 – 334GATA-typePROSITE-ProRule annotationAdd BLAST25

Keywords - Domaini

Zinc-finger

Phylogenomic databases

GeneTreeiENSGT00760000119221.
InParanoidiP43574.
KOiK09184.
OMAiETHSIVH.
OrthoDBiEOG092C43RR.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiIPR013860. DUF1752_fun.
IPR000679. Znf_GATA.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF08550. DUF1752. 1 hit.
PF00320. GATA. 1 hit.
[Graphical view]
PRINTSiPR00619. GATAZNFINGER.
SMARTiSM00401. ZnF_GATA. 1 hit.
[Graphical view]
PROSITEiPS00344. GATA_ZN_FINGER_1. 1 hit.
PS50114. GATA_ZN_FINGER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P43574-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHVFFPLLFR PSPVLFIACA YIYIDIYIHC TRCTVVNITM STNRVPNLDP
60 70 80 90 100
DLNLNKEIWD LYSSAQKILP DSNRILNLSW RLHNRTSFHR INRIMQHSNS
110 120 130 140 150
IMDFSASPFA SGVNAAGPGN NDLDDTDTDN QQFFLSDMNL NGSSVFENVF
160 170 180 190 200
DDDDDDDDVE THSIVHSDLL NDMDSASQRA SHNASGFPNF LDTSCSSSFD
210 220 230 240 250
DHFIFTNNLP FLNNNSINNN HSHNSSHNNN SPSIANNTNA NTNTNTSAST
260 270 280 290 300
NTNSPLLRRN PSPSIVKPGS RRNSSVRKKK PALKKIKSST SVQSSATPPS
310 320 330 340 350
NTSSNPDIKC SNCTTSTTPL WRKDPKGLPL CNACGLFLKL HGVTRPLSLK
360 370 380 390 400
TDIIKKRQRS STKINNNITP PPSSSLNPGA AGKKKNYTAS VAASKRKNSL
410 420 430 440 450
NIVAPLKSQD IPIPKIASPS IPQYLRSNTR HHLSSSVPIE AETFSSFRPD
460 470 480 490 500
MNMTMNMNLH NASTSSFNNE AFWKPLDSAI DHHSGDTNPN SNMNTTPNGN
510
LSLDWLNLNL
Length:510
Mass (Da):56,328
Last modified:November 1, 1995 - v1
Checksum:i62D805E42695F35F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U27344 Genomic DNA. Translation: AAB03516.1.
D50617 Genomic DNA. Translation: BAA09217.1.
BK006940 Genomic DNA. Translation: DAA12419.1.
PIRiS56233.
RefSeqiNP_116632.1. NM_001179945.1.

Genome annotation databases

EnsemblFungiiBAA09217; BAA09217; BAA09217.
YFL021W; YFL021W; YFL021W.
GeneIDi850523.
KEGGisce:YFL021W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U27344 Genomic DNA. Translation: AAB03516.1.
D50617 Genomic DNA. Translation: BAA09217.1.
BK006940 Genomic DNA. Translation: DAA12419.1.
PIRiS56233.
RefSeqiNP_116632.1. NM_001179945.1.

3D structure databases

ProteinModelPortaliP43574.
SMRiP43574.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31125. 35 interactors.
DIPiDIP-4276N.
IntActiP43574. 7 interactors.
MINTiMINT-525395.

PTM databases

iPTMnetiP43574.

Proteomic databases

MaxQBiP43574.
PRIDEiP43574.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiBAA09217; BAA09217; BAA09217.
YFL021W; YFL021W; YFL021W.
GeneIDi850523.
KEGGisce:YFL021W.

Organism-specific databases

EuPathDBiFungiDB:YFL021W.
SGDiS000001873. GAT1.

Phylogenomic databases

GeneTreeiENSGT00760000119221.
InParanoidiP43574.
KOiK09184.
OMAiETHSIVH.
OrthoDBiEOG092C43RR.

Enzyme and pathway databases

BioCyciYEAST:G3O-30439-MONOMER.
ReactomeiR-SCE-5689880. Ub-specific processing proteases.

Miscellaneous databases

PROiP43574.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiIPR013860. DUF1752_fun.
IPR000679. Znf_GATA.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF08550. DUF1752. 1 hit.
PF00320. GATA. 1 hit.
[Graphical view]
PRINTSiPR00619. GATAZNFINGER.
SMARTiSM00401. ZnF_GATA. 1 hit.
[Graphical view]
PROSITEiPS00344. GATA_ZN_FINGER_1. 1 hit.
PS50114. GATA_ZN_FINGER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGAT1_YEAST
AccessioniPrimary (citable) accession number: P43574
Secondary accession number(s): D6VTK9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 142 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1180 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VI
    Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.