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Protein

Bud site selection protein 27

Gene

BUD27

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in gene expression controlled by TOR kinase and nutrient signaling. May also be involved in positioning the proximal bud pole signal.3 Publications

Miscellaneous

Present with 1300 molecules/cell in log phase SD medium.1 Publication
Deletion leads to a K1 killer toxin hypersensitivity.

GO - Molecular functioni

GO - Biological processi

  • formation of translation preinitiation complex Source: SGD
  • replication-born double-strand break repair via sister chromatid exchange Source: SGD
  • RNA polymerase I assembly Source: SGD
  • RNA polymerase II core complex assembly Source: SGD
  • RNA polymerase III assembly Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-30437-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Bud site selection protein 27
Gene namesi
Name:BUD27
Synonyms:URI
Ordered Locus Names:YFL023W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VI

Organism-specific databases

EuPathDBiFungiDB:YFL023W
SGDiS000001871 BUD27

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001536931 – 796Bud site selection protein 27Add BLAST796

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei580PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP43573
PaxDbiP43573
PRIDEiP43573

PTM databases

iPTMnetiP43573

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi31123, 388 interactors
DIPiDIP-4929N
IntActiP43573, 30 interactors
MINTiP43573
STRINGi4932.YFL023W

Structurei

3D structure databases

ProteinModelPortaliP43573
SMRiP43573
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili81 – 121Sequence analysisAdd BLAST41

Sequence similaritiesi

Belongs to the prefoldin subunit alpha family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

GeneTreeiENSGT00730000114241
HOGENOMiHOG000095278
InParanoidiP43573
KOiK17560
OMAiGMYDDDI
OrthoDBiEOG092C0ZXG

Family and domain databases

Gene3Di1.10.287.370, 1 hit
InterProiView protein in InterPro
IPR024325 DUF3835
IPR009053 Prefoldin
IPR004127 Prefoldin_subunit_alpha
PfamiView protein in Pfam
PF12927 DUF3835, 1 hit
PF02996 Prefoldin, 1 hit

Sequencei

Sequence statusi: Complete.

P43573-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLLAASVES TLKNLQDKRN FLSEQREHYI DIRSRLVRFI NDNDDGEEEG
60 70 80 90 100
EGQGMVFGDI IISTSKIYLS LGYEYYVEKT KEEAITFVDD KLKLMEDAIE
110 120 130 140 150
QFNLKIEEAK KTLDNLNHME DGNGIEEDEA NNDEDFLPSM EIREELDDEG
160 170 180 190 200
NVISSSVTPT TKQPSQSNSK KEQTPAVGPK EKGLAKEKKS KSFEENLKGK
210 220 230 240 250
LLKRNDEVKK KVQPSKVDTE NVYTFADLVQ QMDQQDELED GYIETDEINY
260 270 280 290 300
DYDAFENSNF KVNDNYEEDD EDEDEEEYLN HSIIPGFEAQ SSFLQQIQRL
310 320 330 340 350
RAQKQSQDHE REEGDVNKSL KPILKKSSFA ENSDKKQKKK QVGFASSLEI
360 370 380 390 400
HEVENLKEEN KRQMQSFAVP MYETQESTGI ANKMTSDEFD GDLFAKMLGV
410 420 430 440 450
QEADEVHEKY KEELINQERL EGEASRSNRR TRVSRFRKDR ASKKENTLST
460 470 480 490 500
FKQETTRSVE NEVVEKEPVV GDIIEKEPVV GDVIEKEPVV GDVIEKEPAV
510 520 530 540 550
TDIVEREPAV NDIVERKPVV GDIIEKEPTI NDIVEKEPEI NSKSEFETPF
560 570 580 590 600
KKKKLKSLQK PRSSKSMKKK FDPKILENIS DDDYDDDDDG NKKLLSNKSK
610 620 630 640 650
NNTDEQDKFP SKIQEVSRSM AKTGATVGSE PVRITNVDYH ALGGNLDDMV
660 670 680 690 700
KAYSLGLYDD DLEEDPGTIV EKLEDFKEYN KQVELLRDEI RDFQLENKPV
710 720 730 740 750
TMEEEENDGN VMNDIIEHEF PESYTNDEDE VALHPGRLQE EVAIEYRRLK
760 770 780 790
EATASKWQSS SPAAHTEGEL EPIDKFGNPV KTSRFRSQRL HMDSKP
Length:796
Mass (Da):91,422
Last modified:November 1, 1995 - v1
Checksum:i7E2EE2CEB4708BC3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50617 Genomic DNA Translation: BAA09215.1
BK006940 Genomic DNA Translation: DAA12417.1
PIRiS56231
RefSeqiNP_683715.1, NM_001179943.1

Genome annotation databases

EnsemblFungiiBAA09215; BAA09215; BAA09215
YFL023W; YFL023W; YFL023W
GeneIDi850521
KEGGisce:YFL023W

Similar proteinsi

Entry informationi

Entry nameiBUD27_YEAST
AccessioniPrimary (citable) accession number: P43573
Secondary accession number(s): D6VTK7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 25, 2018
This is version 143 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health