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P43569 (CAF16_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 113. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
CCR4-associated factor 16
Gene names
Name:CAF16
Ordered Locus Names:YFL028C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length289 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Interacts with CCR4 and SSN2. Ref.3

Subcellular location

Cytoplasm. Nucleus Ref.4.

Miscellaneous

Present with 1620 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the ABC transporter superfamily.

Contains 1 ABC transporter domain.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

SAH1P399543EBI-22808,EBI-16451

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 289289CCR4-associated factor 16
PRO_0000093464

Regions

Domain7 – 249243ABC transporter
Nucleotide binding41 – 488ATP Potential

Sequences

Sequence LengthMass (Da)Tools
P43569 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 2250CC15F9CE1354

FASTA28933,090
        10         20         30         40         50         60 
MVSQFAIEVR NLTYKFKESS DPSVVDINLQ IPWNTRSLVV GANGAGKSTL LKLLSGKHLC 

        70         80         90        100        110        120 
LDGKILVNGL DPFSPLSMNQ VDDDESVEDS TNYQTTTYLG TEWCHMSIIN RDIGVLELLK 

       130        140        150        160        170        180 
SIGFDHFRER GERLVRILDI DVRWRMHRLS DGQKRRVQLA MGLLKPWRVL LLDEVTVDLD 

       190        200        210        220        230        240 
VIARARLLEF LKWETETRRC SVVYATHIFD GLAKWPNQVY HMKSGKIVDN LDYQKDVEFS 

       250        260        270        280 
EVVNAKVNGQ VAFENDNNKV VISKVNSLHP LALEWLKRDN QIPDKEIGI 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae."
Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T.
Nat. Genet. 10:261-268(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme."
Liu H.-Y., Chiang Y.-C., Pan J., Chen J., Salvadore C., Audino D.C., Badarinarayana V., Palaniswamy V., Anderson B., Denis C.L.
J. Biol. Chem. 276:7541-7548(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH CCR4 AND SSN2.
[4]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D50617 Genomic DNA. Translation: BAA09210.1.
BK006940 Genomic DNA. Translation: DAA12412.1.
PIRS56226.
RefSeqNP_116625.1. NM_001179938.1.

3D structure databases

ProteinModelPortalP43569.
SMRP43569. Positions 7-252.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid31118. 15 interactions.
DIPDIP-5946N.
IntActP43569. 3 interactions.
MINTMINT-4484852.
STRING4932.YFL028C.

Proteomic databases

MaxQBP43569.
PaxDbP43569.
PeptideAtlasP43569.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYFL028C; YFL028C; YFL028C.
GeneID850516.
KEGGsce:YFL028C.

Organism-specific databases

CYGDYFL028c.
SGDS000001866. CAF16.

Phylogenomic databases

eggNOGCOG4586.
HOGENOMHOG000200636.
KOK12608.
OMASTHLIAE.
OrthoDBEOG7WDNCD.

Enzyme and pathway databases

BioCycYEAST:G3O-30432-MONOMER.

Gene expression databases

GenevestigatorP43569.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio966239.

Entry information

Entry nameCAF16_YEAST
AccessionPrimary (citable) accession number: P43569
Secondary accession number(s): D6VTK2
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: June 11, 2014
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VI

Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families