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P43569

- CAF16_YEAST

UniProt

P43569 - CAF16_YEAST

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Protein

CCR4-associated factor 16

Gene
CAF16, YFL028C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi41 – 488ATP Reviewed prediction

GO - Molecular functioni

  1. ATPase activity Source: SGD
  2. ATP binding Source: UniProtKB-KW
  3. protein binding Source: IntAct

GO - Biological processi

  1. ATP catabolic process Source: GOC
  2. regulation of transcription from RNA polymerase II promoter Source: SGD
Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-30432-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
CCR4-associated factor 16
Gene namesi
Name:CAF16
Ordered Locus Names:YFL028C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VI

Organism-specific databases

CYGDiYFL028c.
SGDiS000001866. CAF16.

Subcellular locationi

Cytoplasm. Nucleus 1 Publication

GO - Cellular componenti

  1. CCR4-NOT complex Source: SGD
  2. cytoplasm Source: UniProtKB-SubCell
  3. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 289289CCR4-associated factor 16PRO_0000093464Add
BLAST

Proteomic databases

MaxQBiP43569.
PaxDbiP43569.
PeptideAtlasiP43569.

Expressioni

Gene expression databases

GenevestigatoriP43569.

Interactioni

Subunit structurei

Interacts with CCR4 and SSN2.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
SAH1P399543EBI-22808,EBI-16451

Protein-protein interaction databases

BioGridi31118. 15 interactions.
DIPiDIP-5946N.
IntActiP43569. 3 interactions.
MINTiMINT-4484852.
STRINGi4932.YFL028C.

Structurei

3D structure databases

ProteinModelPortaliP43569.
SMRiP43569. Positions 7-252.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 249243ABC transporterAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG4586.
HOGENOMiHOG000200636.
KOiK12608.
OMAiSTHLIAE.
OrthoDBiEOG7WDNCD.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P43569-1 [UniParc]FASTAAdd to Basket

« Hide

MVSQFAIEVR NLTYKFKESS DPSVVDINLQ IPWNTRSLVV GANGAGKSTL    50
LKLLSGKHLC LDGKILVNGL DPFSPLSMNQ VDDDESVEDS TNYQTTTYLG 100
TEWCHMSIIN RDIGVLELLK SIGFDHFRER GERLVRILDI DVRWRMHRLS 150
DGQKRRVQLA MGLLKPWRVL LLDEVTVDLD VIARARLLEF LKWETETRRC 200
SVVYATHIFD GLAKWPNQVY HMKSGKIVDN LDYQKDVEFS EVVNAKVNGQ 250
VAFENDNNKV VISKVNSLHP LALEWLKRDN QIPDKEIGI 289
Length:289
Mass (Da):33,090
Last modified:November 1, 1995 - v1
Checksum:i2250CC15F9CE1354
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D50617 Genomic DNA. Translation: BAA09210.1.
BK006940 Genomic DNA. Translation: DAA12412.1.
PIRiS56226.
RefSeqiNP_116625.1. NM_001179938.1.

Genome annotation databases

EnsemblFungiiYFL028C; YFL028C; YFL028C.
GeneIDi850516.
KEGGisce:YFL028C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D50617 Genomic DNA. Translation: BAA09210.1 .
BK006940 Genomic DNA. Translation: DAA12412.1 .
PIRi S56226.
RefSeqi NP_116625.1. NM_001179938.1.

3D structure databases

ProteinModelPortali P43569.
SMRi P43569. Positions 7-252.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 31118. 15 interactions.
DIPi DIP-5946N.
IntActi P43569. 3 interactions.
MINTi MINT-4484852.
STRINGi 4932.YFL028C.

Proteomic databases

MaxQBi P43569.
PaxDbi P43569.
PeptideAtlasi P43569.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YFL028C ; YFL028C ; YFL028C .
GeneIDi 850516.
KEGGi sce:YFL028C.

Organism-specific databases

CYGDi YFL028c.
SGDi S000001866. CAF16.

Phylogenomic databases

eggNOGi COG4586.
HOGENOMi HOG000200636.
KOi K12608.
OMAi STHLIAE.
OrthoDBi EOG7WDNCD.

Enzyme and pathway databases

BioCyci YEAST:G3O-30432-MONOMER.

Miscellaneous databases

NextBioi 966239.

Gene expression databases

Genevestigatori P43569.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00005. ABC_tran. 1 hit.
[Graphical view ]
SMARTi SM00382. AAA. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme."
    Liu H.-Y., Chiang Y.-C., Pan J., Chen J., Salvadore C., Audino D.C., Badarinarayana V., Palaniswamy V., Anderson B., Denis C.L.
    J. Biol. Chem. 276:7541-7548(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH CCR4 AND SSN2.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiCAF16_YEAST
AccessioniPrimary (citable) accession number: P43569
Secondary accession number(s): D6VTK2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: June 11, 2014
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1620 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VI
    Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

External Data

Dasty 3

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