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P43562

- YFE0_YEAST

UniProt

P43562 - YFE0_YEAST

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Protein

Probable metabolite transport protein YFL040W

Gene

YFL040W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. substrate-specific transmembrane transporter activity Source: SGD

GO - Biological processi

  1. transmembrane transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-30422-MONOMER.

Protein family/group databases

TCDBi2.A.1.1.100. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Probable metabolite transport protein YFL040W
Gene namesi
Ordered Locus Names:YFL040W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VI

Organism-specific databases

CYGDiYFL040w.
SGDiS000001854. YFL040W.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 540540Probable metabolite transport protein YFL040WPRO_0000050464Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi52 – 521N-linked (GlcNAc...)Sequence Analysis
Glycosylationi374 – 3741N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

GenevestigatoriP43562.

Interactioni

Protein-protein interaction databases

BioGridi31106. 17 interactions.
DIPiDIP-4427N.
IntActiP43562. 4 interactions.
MINTiMINT-517767.
STRINGi4932.YFL040W.

Structurei

3D structure databases

ProteinModelPortaliP43562.
SMRiP43562. Positions 67-480.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2929CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini51 – 6717ExtracellularSequence AnalysisAdd
BLAST
Topological domaini89 – 10113CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini123 – 1264ExtracellularSequence Analysis
Topological domaini148 – 15811CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini180 – 1878ExtracellularSequence Analysis
Topological domaini209 – 27567CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini297 – 31317ExtracellularSequence AnalysisAdd
BLAST
Topological domaini335 – 3417CytoplasmicSequence Analysis
Topological domaini363 – 38523ExtracellularSequence AnalysisAdd
BLAST
Topological domaini407 – 42822CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini450 – 4556ExtracellularSequence Analysis
Topological domaini477 – 54064CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei30 – 5021Helical; Name=1Sequence AnalysisAdd
BLAST
Transmembranei68 – 8821Helical; Name=2Sequence AnalysisAdd
BLAST
Transmembranei102 – 12221Helical; Name=3Sequence AnalysisAdd
BLAST
Transmembranei127 – 14721Helical; Name=4Sequence AnalysisAdd
BLAST
Transmembranei159 – 17921Helical; Name=5Sequence AnalysisAdd
BLAST
Transmembranei188 – 20821Helical; Name=6Sequence AnalysisAdd
BLAST
Transmembranei276 – 29621Helical; Name=7Sequence AnalysisAdd
BLAST
Transmembranei314 – 33421Helical; Name=8Sequence AnalysisAdd
BLAST
Transmembranei342 – 36221Helical; Name=9Sequence AnalysisAdd
BLAST
Transmembranei386 – 40621Helical; Name=10Sequence AnalysisAdd
BLAST
Transmembranei429 – 44921Helical; Name=11Sequence AnalysisAdd
BLAST
Transmembranei456 – 47621Helical; Name=12Sequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0477.
HOGENOMiHOG000141933.
InParanoidiP43562.
OrthoDBiEOG7V4B81.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P43562 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTAMKAIVWR LPKMPKIKIT KTYEVTKITA ILTLVGFIMG LEVPSLATFL
60 70 80 90 100
TNKTFNEYFK YPTPLQQGLL MGSTPLGGIM GCFICCIMND RFSRIYQFQS
110 120 130 140 150
GIIIWNIVTL LNFCIWDILG LLICRMIKGM ILGNFSILVA SYANEVIPRG
160 170 180 190 200
KRGSTMSYIQ LCLTIGILVM HYLCIALSLW DSHFAFRIAW CIGIIPGLLF
210 220 230 240 250
WMASYALPES YHWLVLHGKM SEAQEIQHNL AKKFNESQPR DAVPEMSKIE
260 270 280 290 300
LAGDFWIGVN DLDFSKKLPR GSFKPLILGM TLQLLVQFSG INIILGYITY
310 320 330 340 350
ICEIVGLEGN VKLFTSSIPY FINMVLSLLP ITFIDYTSRK LITLLGGFPI
360 370 380 390 400
SGLLITIGAL FVKYGQDTKP IDGNRSLVWS IGENPFVGGW ILTLCFLIVG
410 420 430 440 450
IFAMSLSSIP WVYTNEMLPS RVKVKGFAIC VTFGWLGNFI LTFLCPVMIE
460 470 480 490 500
RLKGTTFIIF GSLTFLISLS VLIWFPETKG MSIEDIDKFF EFESKEGTNL
510 520 530 540
HGEKGIKTPD SNSNGGSTRS SQEGQLHKPI KLKSDEEMII
Length:540
Mass (Da):60,610
Last modified:November 1, 1995 - v1
Checksum:iA43B6B58134C38AE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D50617 Genomic DNA. Translation: BAA09200.1.
BK006940 Genomic DNA. Translation: DAA12400.1.
PIRiS56215.
RefSeqiNP_116613.1. NM_001179926.1.

Genome annotation databases

EnsemblFungiiYFL040W; YFL040W; YFL040W.
GeneIDi850503.
KEGGisce:YFL040W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D50617 Genomic DNA. Translation: BAA09200.1 .
BK006940 Genomic DNA. Translation: DAA12400.1 .
PIRi S56215.
RefSeqi NP_116613.1. NM_001179926.1.

3D structure databases

ProteinModelPortali P43562.
SMRi P43562. Positions 67-480.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 31106. 17 interactions.
DIPi DIP-4427N.
IntActi P43562. 4 interactions.
MINTi MINT-517767.
STRINGi 4932.YFL040W.

Protein family/group databases

TCDBi 2.A.1.1.100. the major facilitator superfamily (mfs).

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YFL040W ; YFL040W ; YFL040W .
GeneIDi 850503.
KEGGi sce:YFL040W.

Organism-specific databases

CYGDi YFL040w.
SGDi S000001854. YFL040W.

Phylogenomic databases

eggNOGi COG0477.
HOGENOMi HOG000141933.
InParanoidi P43562.
OrthoDBi EOG7V4B81.

Enzyme and pathway databases

BioCyci YEAST:G3O-30422-MONOMER.

Miscellaneous databases

NextBioi 966203.

Gene expression databases

Genevestigatori P43562.

Family and domain databases

InterProi IPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR005829. Sugar_transporter_CS.
[Graphical view ]
Pfami PF00083. Sugar_tr. 1 hit.
[Graphical view ]
SUPFAMi SSF103473. SSF103473. 1 hit.
PROSITEi PS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.

Entry informationi

Entry nameiYFE0_YEAST
AccessioniPrimary (citable) accession number: P43562
Secondary accession number(s): D6VTJ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 29, 2014
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VI
    Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

External Data

Dasty 3