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Protein

Probable metabolite transport protein YFL040W

Gene

YFL040W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • glucose import Source: GO_Central
  • hexose transmembrane transport Source: GO_Central
  • transmembrane transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-30422-MONOMER.

Protein family/group databases

TCDBi2.A.1.1.100. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Probable metabolite transport protein YFL040W
Gene namesi
Ordered Locus Names:YFL040W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VI

Organism-specific databases

EuPathDBiFungiDB:YFL040W.
SGDiS000001854. YFL040W.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 29CytoplasmicSequence analysisAdd BLAST29
Transmembranei30 – 50Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini51 – 67ExtracellularSequence analysisAdd BLAST17
Transmembranei68 – 88Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini89 – 101CytoplasmicSequence analysisAdd BLAST13
Transmembranei102 – 122Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini123 – 126ExtracellularSequence analysis4
Transmembranei127 – 147Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini148 – 158CytoplasmicSequence analysisAdd BLAST11
Transmembranei159 – 179Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini180 – 187ExtracellularSequence analysis8
Transmembranei188 – 208Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini209 – 275CytoplasmicSequence analysisAdd BLAST67
Transmembranei276 – 296Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini297 – 313ExtracellularSequence analysisAdd BLAST17
Transmembranei314 – 334Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini335 – 341CytoplasmicSequence analysis7
Transmembranei342 – 362Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini363 – 385ExtracellularSequence analysisAdd BLAST23
Transmembranei386 – 406Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini407 – 428CytoplasmicSequence analysisAdd BLAST22
Transmembranei429 – 449Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini450 – 455ExtracellularSequence analysis6
Transmembranei456 – 476Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini477 – 540CytoplasmicSequence analysisAdd BLAST64

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000504641 – 540Probable metabolite transport protein YFL040WAdd BLAST540

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi52N-linked (GlcNAc...)Sequence analysis1
Glycosylationi374N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

BioGridi31106. 18 interactors.
DIPiDIP-4427N.
IntActiP43562. 4 interactors.
MINTiMINT-517767.

Structurei

3D structure databases

ProteinModelPortaliP43562.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000141933.
InParanoidiP43562.
OrthoDBiEOG092C1BNC.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P43562-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAMKAIVWR LPKMPKIKIT KTYEVTKITA ILTLVGFIMG LEVPSLATFL
60 70 80 90 100
TNKTFNEYFK YPTPLQQGLL MGSTPLGGIM GCFICCIMND RFSRIYQFQS
110 120 130 140 150
GIIIWNIVTL LNFCIWDILG LLICRMIKGM ILGNFSILVA SYANEVIPRG
160 170 180 190 200
KRGSTMSYIQ LCLTIGILVM HYLCIALSLW DSHFAFRIAW CIGIIPGLLF
210 220 230 240 250
WMASYALPES YHWLVLHGKM SEAQEIQHNL AKKFNESQPR DAVPEMSKIE
260 270 280 290 300
LAGDFWIGVN DLDFSKKLPR GSFKPLILGM TLQLLVQFSG INIILGYITY
310 320 330 340 350
ICEIVGLEGN VKLFTSSIPY FINMVLSLLP ITFIDYTSRK LITLLGGFPI
360 370 380 390 400
SGLLITIGAL FVKYGQDTKP IDGNRSLVWS IGENPFVGGW ILTLCFLIVG
410 420 430 440 450
IFAMSLSSIP WVYTNEMLPS RVKVKGFAIC VTFGWLGNFI LTFLCPVMIE
460 470 480 490 500
RLKGTTFIIF GSLTFLISLS VLIWFPETKG MSIEDIDKFF EFESKEGTNL
510 520 530 540
HGEKGIKTPD SNSNGGSTRS SQEGQLHKPI KLKSDEEMII
Length:540
Mass (Da):60,610
Last modified:November 1, 1995 - v1
Checksum:iA43B6B58134C38AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50617 Genomic DNA. Translation: BAA09200.1.
BK006940 Genomic DNA. Translation: DAA12400.1.
PIRiS56215.
RefSeqiNP_116613.1. NM_001179926.1.

Genome annotation databases

EnsemblFungiiBAA09200; BAA09200; BAA09200.
YFL040W; YFL040W; YFL040W.
GeneIDi850503.
KEGGisce:YFL040W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50617 Genomic DNA. Translation: BAA09200.1.
BK006940 Genomic DNA. Translation: DAA12400.1.
PIRiS56215.
RefSeqiNP_116613.1. NM_001179926.1.

3D structure databases

ProteinModelPortaliP43562.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31106. 18 interactors.
DIPiDIP-4427N.
IntActiP43562. 4 interactors.
MINTiMINT-517767.

Protein family/group databases

TCDBi2.A.1.1.100. the major facilitator superfamily (mfs).

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiBAA09200; BAA09200; BAA09200.
YFL040W; YFL040W; YFL040W.
GeneIDi850503.
KEGGisce:YFL040W.

Organism-specific databases

EuPathDBiFungiDB:YFL040W.
SGDiS000001854. YFL040W.

Phylogenomic databases

HOGENOMiHOG000141933.
InParanoidiP43562.
OrthoDBiEOG092C1BNC.

Enzyme and pathway databases

BioCyciYEAST:G3O-30422-MONOMER.

Miscellaneous databases

PROiP43562.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYFE0_YEAST
AccessioniPrimary (citable) accession number: P43562
Secondary accession number(s): D6VTJ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 30, 2016
This is version 136 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VI
    Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.