P43557 (FMP32_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein FMP32, mitochondrial

Alternative name(s):
Found in mitochondrial proteome protein 32

Gene names

Name:	FMP32
Ordered Locus Names:	YFL046W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	207 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Mitochondrion. Membrane; Single-pass membrane protein Potential Ref.4 Ref.5 Ref.6 Ref.7.
Sequence similarities	Belongs to the CCDC90 family.

Ontologies

Keywords
Cellular component	Membrane Mitochondrion
Domain	Coiled coil Transit peptide Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrion Inferred from direct assay Ref.4Ref.6Ref.7. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – ?		Mitochondrion Potential
	Chain	? – 207		Protein FMP32, mitochondrial		PRO_0000202671
Regions
	Transmembrane	184 – 206	23	Helical; Potential
	Coiled coil	100 – 136	37	Potential

Sequences

	Sequence		Length	Mass (Da)
	P43557 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 0EA7B6122421ACB3	FASTA	207	24,019
	10 20 30 40 50 60 MLKRIVGLPA RRCFHRTSFL LGSDFETVHI PNTNHFKDLL IENGKFQEDQ ATTIVEIMTD 70 80 90 100 110 120 AIRGGVNHVS QDLAKREKLT QLSYQQRVDF AKLRDQLLSA DRSEFHNIQN EYESVKNDLE 130 140 150 160 170 180 KLRNKLREEI TKTNAGFKLD LSLEKGRIRE ESSHHDLQIK EIDTKIEQEV TNMKMQIDSV 190 200 KTQVMQWLIG VCTGTFALVL AYMRLLT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae." Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T. Nat. Genet. 10:261-268(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[4]	"Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae." Beilharz T., Egan B., Silver P.A., Hofmann K., Lithgow T. J. Biol. Chem. 278:8219-8223(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION.
[5]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]	"The proteome of Saccharomyces cerevisiae mitochondria." Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E., Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C. Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY. Strain: ATCC 76625 / YPH499.
[7]	"Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics." Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A. J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D50617 Genomic DNA. Translation: BAA09195.1. AY558468 Genomic DNA. Translation: AAS56794.1. BK006940 Genomic DNA. Translation: DAA12394.1.
PIR	S56209.
RefSeq	NP_116608.1. NM_001179921.1.
3D structure databases
ProteinModelPortal	P43557.
ModBase	Search...
Protein-protein interaction databases
IntAct	P43557. 2 interactions.
STRING	4932.YFL046W.
Proteomic databases
PaxDb	P43557.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YFL046W; YFL046W; YFL046W.
GeneID	850498.
KEGG	sce:YFL046W.
Organism-specific databases
CYGD	YFL046w.
SGD	S000001848. FMP32.
Phylogenomic databases
eggNOG	NOG289986.
GeneTree	ENSGT00390000016409.
HOGENOM	HOG000247902.
OMA	MQWLIGV.
OrthoDB	EOG4GBBGJ.
Gene expression databases
Genevestigator	P43557.
GermOnline	YFL046W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR012439. Coiled-coil-containing_90. IPR024461. DUF1640. [Graphical view]
PANTHER	PTHR14360:SF1. PTHR14360:SF1. 1 hit.
Pfam	PF07798. DUF1640. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	966188.

Entry information

Entry name

FMP32_YEAST

Accession

Primary (citable) accession number: P43557
Secondary accession number(s): D6VTI4

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	April 3, 2013
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program