Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P43554

- SWP82_YEAST

UniProt

P43554 - SWP82_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

SWI/SNF global transcription activator complex subunit SWP82

Gene

SWP82

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli

Functioni

Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.

GO - Biological processi

  1. ATP catabolic process Source: GOC
  2. chromatin modification Source: UniProtKB-KW
  3. positive regulation of transcription from RNA polymerase II promoter Source: SGD
  4. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator, Chromatin regulator

Keywords - Biological processi

Transcription, Transcription regulation

Enzyme and pathway databases

BioCyciYEAST:G3O-30416-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
SWI/SNF global transcription activator complex subunit SWP82
Gene namesi
Name:SWP82
Ordered Locus Names:YFL049W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VI

Organism-specific databases

CYGDiYFL049w.
SGDiS000001845. SWP82.

Subcellular locationi

Nucleus 1 Publication

GO - Cellular componenti

  1. cytosol Source: SGD
  2. nucleus Source: SGD
  3. SWI/SNF complex Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 623623SWI/SNF global transcription activator complex subunit SWP82PRO_0000076350Add
BLAST

Proteomic databases

MaxQBiP43554.
PaxDbiP43554.
PeptideAtlasiP43554.

Expressioni

Gene expression databases

GenevestigatoriP43554.

Interactioni

Subunit structurei

Interacts with SWI3 and SNF12. Component of the SWI/SNF global transcription activator complex. The 1.14 MDa SWI/SNF complex is composed of 11 different subunits: one copy each of SWI1, SNF2/SWI2, SNF5, SNF12/SWP73, ARP7/SWP61, ARP9/SWP59; two copies each of SWI3, SNF6, SNF11, SWP82; and three copies of TAF14/SWP29.1 Publication

Protein-protein interaction databases

BioGridi31098. 35 interactions.
DIPiDIP-4202N.
IntActiP43554. 15 interactions.
MINTiMINT-548310.
STRINGi4932.YFL049W.

Structurei

3D structure databases

ProteinModelPortaliP43554.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RSC7/SWP82 family. SWP82 subfamily.Curated

Phylogenomic databases

eggNOGiNOG73202.
GeneTreeiENSGT00530000067789.
HOGENOMiHOG000141929.
InParanoidiP43554.
KOiK11776.
OMAiNINGWKF.
OrthoDBiEOG7D59ZJ.

Family and domain databases

InterProiIPR013933. CRC_Rsc7/Swp82.
[Graphical view]
PfamiPF08624. CRC_subunit. 1 hit.
[Graphical view]
ProDomiPD041931. CRC_Rsc7/Swp82. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

P43554-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLGEDEGNTV LEKGNNPSVK QGEVGAVFIV PKILIREHER VILKQILQIL
60 70 80 90 100
DQDELVQPPL DKFPYKKLEL PKYIDELKTR DATNTSYKMI QLDAYGEKKV
110 120 130 140 150
GSNGELFGGR HYLFNTFTFT AHMGVLLVLL QDVIKVLYQS NATHDEDEFI
160 170 180 190 200
VQHDQILVME TSEEQTKFLA KNGVIPEESK GSFKYITARS AFVEFGASVI
210 220 230 240 250
AGGQRIVDDY WESLAKKQNL SSHQRVFKLS TNLISKISLL RPSFQNNRIS
260 270 280 290 300
NANEISANTN NTCTISTSKF ESQYPIVTEQ PSAEIREAYI ENFAKGEHIS
310 320 330 340 350
AIVPGQSISG TLELSAQFRV PRYHSKNSFQ QALQMKAMDI PIGRHEELLA
360 370 380 390 400
QYESQAPDGS ASISLPNHIP SVNPSNKPIK RMLSSILDIN VSSSKNKKSE
410 420 430 440 450
ENEMIKPMNK GQHKNNTSLN INGWKFESLP LKSAENSGKQ QYYRGLPLYE
460 470 480 490 500
KNTLLERLKQ LTPNEIKELE HLHDAVFVNT GLQNVRKVRT KKWKKYWQYK
510 520 530 540 550
AGIPIGLKRS QLDEFKNKYL KDVLAQTSVT TNFNEITNTD ETITTKRVPN
560 570 580 590 600
PNFLGNCNIK DFKPPYIYSH VNKVPQNVAG DKTAVKLDTE VKNTNANPVV
610 620
ATDPVAAKPD NLANFSNEVA MNN
Length:623
Mass (Da):70,276
Last modified:November 1, 1995 - v1
Checksum:iA8AC00CAC8F0ED0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50617 Genomic DNA. Translation: BAA09192.1.
BK006940 Genomic DNA. Translation: DAA12391.1.
PIRiS56206.
RefSeqiNP_116605.1. NM_001179918.1.

Genome annotation databases

EnsemblFungiiYFL049W; YFL049W; YFL049W.
GeneIDi850495.
KEGGisce:YFL049W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50617 Genomic DNA. Translation: BAA09192.1 .
BK006940 Genomic DNA. Translation: DAA12391.1 .
PIRi S56206.
RefSeqi NP_116605.1. NM_001179918.1.

3D structure databases

ProteinModelPortali P43554.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 31098. 35 interactions.
DIPi DIP-4202N.
IntActi P43554. 15 interactions.
MINTi MINT-548310.
STRINGi 4932.YFL049W.

Proteomic databases

MaxQBi P43554.
PaxDbi P43554.
PeptideAtlasi P43554.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YFL049W ; YFL049W ; YFL049W .
GeneIDi 850495.
KEGGi sce:YFL049W.

Organism-specific databases

CYGDi YFL049w.
SGDi S000001845. SWP82.

Phylogenomic databases

eggNOGi NOG73202.
GeneTreei ENSGT00530000067789.
HOGENOMi HOG000141929.
InParanoidi P43554.
KOi K11776.
OMAi NINGWKF.
OrthoDBi EOG7D59ZJ.

Enzyme and pathway databases

BioCyci YEAST:G3O-30416-MONOMER.

Miscellaneous databases

NextBioi 966179.

Gene expression databases

Genevestigatori P43554.

Family and domain databases

InterProi IPR013933. CRC_Rsc7/Swp82.
[Graphical view ]
Pfami PF08624. CRC_subunit. 1 hit.
[Graphical view ]
ProDomi PD041931. CRC_Rsc7/Swp82. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  5. "Structural analysis of the yeast SWI/SNF chromatin remodeling complex."
    Smith C.L., Horowitz-Scherer R., Flanagan J.F., Woodcock C.L., Peterson C.L.
    Nat. Struct. Biol. 10:141-145(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: 3D-STRUCTURE MODELING OF THE SWI/SNF COMPLEX, ELECTRON MICROSCOPY OF THE SWI/SNF COMPLEX.
  6. "The RSC chromatin remodeling complex bears an essential fungal-specific protein module with broad functional roles."
    Wilson B., Erdjument-Bromage H., Tempst P., Cairns B.R.
    Genetics 172:795-809(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE SWI/SNF COMPLEX, INTERACTION WITH SWI3 AND SNF12.

Entry informationi

Entry nameiSWP82_YEAST
AccessioniPrimary (citable) accession number: P43554
Secondary accession number(s): D6VTI1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 29, 2014
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 3180 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VI
    Yeast (Saccharomyces cerevisiae) chromosome VI: entries and gene names

External Data

Dasty 3